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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Metastatic Colorectal Cancer (Mcrc)

A Comparative Study of Pharmacokinetics, Safety, and Immunogenicity of RPH-030 and Vectibixยฎ in Patients With Metastatic Colorectal Cancer With Wild-type RAS as First-line Therapy in Combination With FOLFIRI NCT07543744Phase 126 sites๐Ÿ“ Arkhangelsk๐Ÿ“ Istra๐Ÿ“ Ivanovo R-Pharm ยท Tests: RPH-030, Vectibixยฎ, Irinotecan, Calcium Folinate, Fluorouracil Evaluation of a Diagnostic Test to Identify the Best Drugs for Treatment of Metastatic Colorectal Cancer NCT07171554NA1 site๐Ÿ“ Lรธrenskog Oncosyne AS ยท Tests: ยตCAN drug screen test, Standard-of-Care Therapy Evaluation of Irinotecan Liposome (II) Combined With 5-FU, LV, and Bevacizumab for mCRC NCT06643793Phase 21 site๐Ÿ“ Nanjing Affiliated Hospital of Nantong University ยท Tests: Irinotecan liposome (ll) + 5-FU/LV + bevacizumab Development of a cfDNA 5mC/5hmC-based Biomarker Panel to Predict Targeted Therapy Efficacy in mCRC NCT07224841n/a1 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: cfDNA 5mC/5hmC Sequencing (EpiDRIVE Discovery Phase), EpiDRIVE Assay (Targeted Sequencing / qPCR Validation) LYL273 for Patients With Relapsed or Refractory mCRC NCT05319314Phase 1, Phase 25 sites๐Ÿ“ Duarte๐Ÿ“ San Francisco๐Ÿ“ Aurora Lyell Immunopharma, Inc. ยท Tests: LYL273 Cetuximab Plus Irinotecan in Patients With NeoRAS Wild-type Metastatic Colorectal Cancer In Third-line Therapy NCT05962502Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Cetuximab and irinotecan A Clinical Study to Evaluate Efficacy and Safety of Serplulimab๏ผˆHLX10๏ผ‰ Combined With Bevacizumab๏ผˆHLX04) and Chemotherapy (XELOX) in Patients With Metastatic Colorectal Cancer (mCRC) NCT04547166Phase 2, Phase 35 sites๐Ÿ“ Guangzhou๐Ÿ“ Hangzhou๐Ÿ“ Linyi Shanghai Henlius Biotech ยท Tests: HLX10, HLX04ใ€ AGMT Metastatic Colorectal Cancer Registry (mCRC) Third Line and Beyond NCT06678919n/a7 sites๐Ÿ“ Linz๐Ÿ“ Linz๐Ÿ“ Rankweil Arbeitsgemeinschaft medikamentoese Tumortherapie A Study on Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer (mCRC) NCT06749015n/a1 site๐Ÿ“ Shanghai Fudan University ยท Tests: Non interventional study A FIH, Phase I/IIa, Trial Assessing Feasibility of Administrations of TIL-based Immunotherapy in Patients With Metastatic CRC and PC NCT07255664Phase 1, Phase 21 site๐Ÿ“ Frankfurt CuraCell TX AB ยท Tests: CC-38, Pembrolizumab, Cyclophosphamid, Interleukin-2, Uromitexan Assessing the Efficacy and Safety of ctDNA-driven Selection for Anti-EGFR Retreatment in a Real World Metastatic Colorectal Cancer Patients Cohort (the REalCHALLENGE Study) NCT07536113n/a1 site๐Ÿ“ Milan Niguarda Hospital Streamlining Radioembolization for CCC and Metastatic Liver Cancer NCT07043387n/a4 sites๐Ÿ“ Goyang-si๐Ÿ“ Seoul๐Ÿ“ Seoul Seoul National University Hospital FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer NCT07446322Phase 219 sites๐Ÿ“ Homewood๐Ÿ“ Beverly Hills๐Ÿ“ Encino Oncolytics Biotech ยท Tests: Bevacizumab, FOLFIRI, Pelareorep Upfront Trastuzumab-Deruxtecan Plus Capecitabine and Bevacizumab for Patients With HER-2 Positive Metastatic Colorectal Cancer. NCT07407465Phase 228 sites๐Ÿ“ Lyon๐Ÿ“ Marseille๐Ÿ“ Paris Gruppo Oncologico del Nord-Ovest ยท Tests: Trastuzumab-Deruxtecan (T-DXd), Capecitabine, Bevacizumab A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL) NCT07011576Phase 214 sites๐Ÿ“ Denver๐Ÿ“ Arlington Heights๐Ÿ“ Columbia SCRI Development Innovations, LLC ยท Tests: fruquintinib, FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin) DHF-20-1839-2: Clinical Performance Study Protocol for Therascreenยฎ KRAS RGQ PCR Kit NCT06645236NA1 site๐Ÿ“ Manchester QIAGEN Gaithersburg, Inc ยท Tests: therascreenยฎ KRAS RGQ PCR Kit Metformin for the Treatment of mCRC Patients Undergoing FOLFIRI Plus Target Therapy NCT06826092Phase 21 site๐Ÿ“ Kaohsiung City Kaohsiung Medical University Chung-Ho Memorial Hospital ยท Tests: Metformin Pill, FOLFIRI plus target therapy only A Study of ASP1002 in Adults for Treatment of Solid Tumors NCT05719558Phase 115 sites๐Ÿ“ New Haven๐Ÿ“ Plainville๐Ÿ“ Gainesville Astellas Pharma Global Development, Inc. ยท Tests: ASP1002, Bevacizumab, Oxaliplatin, Leucovorin, Fluorouracil A Study to Investigate CEA-PRIT 2.0 in Participants With Metastatic Colorectal Cancer (mCRC) NCT07416552Phase 15 sites๐Ÿ“ Chicago๐Ÿ“ St Louis๐Ÿ“ Omaha Hoffmann-La Roche ยท Tests: SPLIT Abs, 203Pb-DOTAM, 212Pb-DOTAM Using ctDNA Methylation to Monitor Metastatic Colorectal Cancer Treatment (PROMET) NCT07283575n/a1 site๐Ÿ“ Shanghai Fudan University ยท Tests: Plasma ctDNA methylation profiling Exosome-derived Extrahepatic Metastasis Detection By Liquid Biopsy In Colorectal Cancer Liver Metastases NCT07224724n/a1 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: EXELION PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma NCT05286814Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Dexamethasone, PDS01ADC, Intera 3000 Hepatic Artery Infusion Pump (HAIP), Floxuridine ctDNA Monitoring in Patients With HCC and mCRC NCT07001085NA1 site๐Ÿ“ Warsaw Medical University of Warsaw ยท Tests: Tumor Tissue Collection and NGS, Blood Collection for Plasma ctDNA, ctDNA Mutation Analysis via ddPCR A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer NCT07221357Phase 2, Phase 3286 sites๐Ÿ“ Tucson๐Ÿ“ Springdale๐Ÿ“ Los Angeles Bristol-Myers Squibb ยท Tests: Pumitamig, FOLFOX, FOLFIRI, Bevacizumab, CAPOX TATE and Pembrolizumab (MK3475) in mCRC and NSCLC NCT04701476Phase 23 sites๐Ÿ“ Orange๐Ÿ“ Hsinchu๐Ÿ“ Taichung Teclison Ltd. ยท Tests: TATE and pembrolizumab, TAS-102 pill, Regorafenib Pill Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer NCT07228832Phase 3236 sites๐Ÿ“ Mobile๐Ÿ“ Tuscaloosa๐Ÿ“ Goodyear Summit Therapeutics ยท Tests: Drug: Ivonescimab Injection, Drug: Bevacizumab Injection ARTEMIS-102: HS-20093 Combinations in Patients with Advanced Metastatic Colorectal Cancer NCT06825624Phase 11 site๐Ÿ“ Hangzhou Hansoh BioMedical R&D Company ยท Tests: HS-20093, Bevacizumab, 5-FU, Leucovorin, Capecitabine Low-dose Trifluridine/Tipiracil With Bevacizumab in mCRC NCT07085169Phase 22 sites๐Ÿ“ Sanming๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: Trifluridine/tipiracil (TAS-102) plus bevacizumab Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer NCT07222800Phase 3372 sites๐Ÿ“ Chandler๐Ÿ“ Gilbert๐Ÿ“ Gilbert Pfizer ยท Tests: PF-08634404, Bevacizumab, Chemotherapy Continuation of Cetuximab Beyond First-Line Progression in Metastatic Colorectal Cancer NCT07389265Phase 341 sites๐Ÿ“ Ancona๐Ÿ“ Avellino๐Ÿ“ Aviano University of Campania Luigi Vanvitelli ยท Tests: Erbitux (Cetuximab), Bevacizumab, FOLFOX (Folinic acid + Fluorouracil + Oxaliplatin), FOLFIRI (5-Fluorouracil, Folinic โ€ฆ
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