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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Metastatic Esophageal Squamous Cell Carcinoma

A Trial of the Combination of Afatinib and Palbociclib in Previously Treated Advanced Esophageal Squamous Cell Carcinoma NCT06753747Phase 1, Phase 21 site๐Ÿ“ Chengdu West China Hospital ยท Tests: Palbociclib, Afatinib(30mg), Afatinib(40mg), Afatinib(RP2D) A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies NCT05473156Phase 1, Phase 21 site๐Ÿ“ Taipei AP Biosciences Inc. ยท Tests: AP203, AP203 A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors NCT07277413Phase 123 sites๐Ÿ“ Goodyear๐Ÿ“ Phoenix๐Ÿ“ Duarte IDEAYA Biosciences ยท Tests: IDE892, IDE397 A Study of IDP-001 in Advanced or Metastatic Solid Tumors NCT07602842Phase 1, Phase 26 sites๐Ÿ“ Los Angeles๐Ÿ“ Sarasota๐Ÿ“ Indianapolis InduPro, Inc. ยท Tests: IDP-001 Sintilimab and Chemotherapy Sequential Radiotherapy in Advanced Esophageal Cancer NCT06138028Phase 2, Phase 32 sites๐Ÿ“ Qingdao๐Ÿ“ Qingdao Qingdao Central Hospital ยท Tests: TP regimen (cis-platinum ; Tocetaxel ) combined with PD-1 inhibitors๏ผˆSintilimab๏ผ‰ A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types NCT07503808Phase 115 sites๐Ÿ“ Denver๐Ÿ“ Sarasota๐Ÿ“ Detroit IDEAYA Biosciences ยท Tests: IDE034 Radiotherapy Combined With Immunochemotherapy in Metastatic Esophageal Squamous Cell Carcinoma NCT05978193Phase 22 sites๐Ÿ“ Shanghai๐Ÿ“ Shanghai Shanghai Chest Hospital ยท Tests: LDRT+CFRT, Immunotherapy, Chemotherapy KC1036 in Combination With PD-1 Antibody and Platinum-based Chemotherapy for First-line Advanced Esophageal Cancer NCT07481058Phase 21 site๐Ÿ“ Beijing Beijing Konruns Pharmaceutical Co., Ltd. ยท Tests: KC1036, Toripalimab, Paclitaxel, Cisplatin, KC1036 A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors NCT07229313Phase 17 sites๐Ÿ“ Santa Monica๐Ÿ“ New Have๐Ÿ“ Camperdown Kivu Bioscience Inc. ยท Tests: KIVU-107 A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors NCT06657144Phase 130 sites๐Ÿ“ Tucson๐Ÿ“ Duarte๐Ÿ“ Aurora Coherus Oncology, Inc. ยท Tests: CHS-114, Toripalimab, 5 Fluorouracil, Cisplatin Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers NCT00900419n/a1 site๐Ÿ“ Aurora University of Colorado, Denver ยท Tests: immunohistochemistry staining method, laboratory biomarker analysis, sputum cytology, biopsy A Clinical Trial of Ifinatamab Deruxtecan in People With Advanced Esophageal Cancer (MK-3475-06F) NCT07405151Phase 1, Phase 232 sites๐Ÿ“ Pittsburgh๐Ÿ“ Natal๐Ÿ“ Porto Alegre Merck Sharp & Dohme LLC ยท Tests: I-DXd, Rescue Medication A Study of YL201 Versus Investigator's Choice of Chemotherapy in Participants With Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-Line Therapy NCT07487896Phase 381 sites๐Ÿ“ Anqing๐Ÿ“ Bengbu๐Ÿ“ Hefei MediLink Therapeutics (Suzhou) Co., Ltd. ยท Tests: YL201, Paclitaxel, Docetaxel, Irinotecan A Study Investigating Alternate Schedules of Tislelizumab Plus Chemotherapy in Japanese Patients With First-line Advanced ESCC NCT07733180Phase 24 sites๐Ÿ“ Yokohama๐Ÿ“ Takatsukishi๐Ÿ“ ChuoKu BeOne Medicines ยท Tests: Tislelizumab, Oxaliplatin, Leucovorin, 5-fluorouracil (5-FU) A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors NCT05914116Phase 1, Phase 2107 sites๐Ÿ“ Tucson๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles DualityBio Inc. ยท Tests: DB-1311, Lopinavir and Ritonavir Tablets, itraconazole, Enzalutamide, Abiraterone A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer NCT07227168Phase 19 sites๐Ÿ“ San Diego๐Ÿ“ Denver๐Ÿ“ Washington D.C. Sutro Biopharma, Inc. ยท Tests: STRO-004, Pembrolizumab A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors NCT03526835Phase 1, Phase 254 sites๐Ÿ“ La Jolla๐Ÿ“ Los Angeles๐Ÿ“ San Diego Merus B.V. ยท Tests: MCLA-158, MCLA-158 + Pembrolizumab, MCLA-158 + FOLFIRI, MCLA-158 + FOLFOX A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors NCT05592626Phase 1, Phase 219 sites๐Ÿ“ Sacramento๐Ÿ“ Celebration๐Ÿ“ Miami Marengo Therapeutics, Inc. ยท Tests: STAR0602, Irinotecan (Camptosar), Docetaxel (Taxotere) Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers NCT04221893NA2 sites๐Ÿ“ San Francisco๐Ÿ“ Walnut Creek University of California, San Francisco ยท Tests: Radiation Therapy (RT) Study of XB010 in Subjects With Solid Tumors NCT06545331Phase 120 sites๐Ÿ“ Irvine๐Ÿ“ Los Angeles๐Ÿ“ Washington D.C. Exelixis ยท Tests: XB010, Pembrolizumab A Study of [225Ac]Ac-AKY-2519 in Patients With B7-H3 Expressing Solid Tumors NCT07887971Phase 11 site๐Ÿ“ Miami Aktis Oncology, Inc. ยท Tests: [225Ac]Ac-AKY-2519 (therapeutic), [64Cu]Cu-AKY-2519 (imaging) A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors NCT06248411Phase 114 sites๐Ÿ“ Nagoya๐Ÿ“ Kashiwa๐Ÿ“ Matsuyama Kyowa Kirin Co., Ltd. ยท Tests: KK2260, KK2260 A Study of MGC026 in Participants With Advanced Solid Tumors NCT06242470Phase 112 sites๐Ÿ“ Los Angeles๐Ÿ“ Grand Rapids๐Ÿ“ Lake Success MacroGenics ยท Tests: MGC026 Dose Escalation, MGC026 Dose for Expansion A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma in Racial and Ethnic Minority Patients in the United States NCT07554521Phase 29 sites๐Ÿ“ Bullhead City๐Ÿ“ Cerritos๐Ÿ“ Los Angeles BeOne Medicines ยท Tests: Tislelizumab, Capecitabine, 5-fluorouracil (5-FU), Oxaliplatin, Leucovorin A Study of SH009 Injection in Patients With Advanced Solid Tumors. NCT07390838Phase 11 site๐Ÿ“ Shanghai Nanjing Sanhome Pharmaceutical, Co., Ltd. ยท Tests: SH009 Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors NCT06975410Phase 1, Phase 24 sites๐Ÿ“ Seoul๐Ÿ“ Seoul๐Ÿ“ Seoul Yuhan Corporation ยท Tests: YH32364 Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06) NCT06780111Phase 1, Phase 250 sites๐Ÿ“ Pittsburgh๐Ÿ“ Natal๐Ÿ“ Porto Alegre Merck Sharp & Dohme LLC ยท Tests: Pembrolizumab, I-DXd, Leucovorin, Levoleucovorin, 5-Fluorouracil (5-FU) First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors NCT07284186Phase 110 sites๐Ÿ“ Scottsdale๐Ÿ“ Duarte๐Ÿ“ Orange Plexium, Inc. ยท Tests: PLX-61639 Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rฮฑ Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer NCT05267626Phase 1, Phase 217 sites๐Ÿ“ Miami๐Ÿ“ Grand Rapids๐Ÿ“ Minneapolis Aulos Bioscience, Inc. ยท Tests: AU-007, Aldesleukin, Avelumab, Nivolumab Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors NCT05983432Phase 137 sites๐Ÿ“ Beverly Hills๐Ÿ“ Duarte๐Ÿ“ Orange SystImmune Inc. ยท Tests: BL-B01D1
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