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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Metastatic Pancreatic Ductal Adenocarcinoma

The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation NCT06843551Phase 21 site๐Ÿ“ Miami Benjamin Spieler ยท Tests: Stereotactic Body Radiation Therapy, Botensilimab, Balstilimab Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC) NCT07217717Phase 319 sites๐Ÿ“ Cerritos๐Ÿ“ Duarte๐Ÿ“ Irvine SOFIE ยท Tests: [18F]FAPI-74 PET/CT A Study of CEND-1 With Chemotherapy as First-Line Therapy in Patients With Pancreatic Ductal Adenocarcinoma NCT06261359Phase 21 site๐Ÿ“ Beijing Qilu Pharmaceutical Co., Ltd. ยท Tests: CEND-1, Gemcitabine, Nab paclitaxel Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC NCT07145450Phase 1, Phase 210 sites๐Ÿ“ Copenhagen๐Ÿ“ Berlin๐Ÿ“ Dresden Anocca AB ยท Tests: ANOC-001 (TCR-T cells targeting KRAS G12V mutation presented by specific HLA alleles), ANOC-002 (TCR-T cells targeting โ€ฆ AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors NCT07094113Phase 139 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Atlanta Amgen ยท Tests: AMG 410, Pembrolizumab, Panitumumab Intraperitoneal Paclitaxel With NALIRIFOX for Pancreatic Ductal Adenocarcinoma With Peritoneal Carcinomatosis NCT07030283Phase 11 site๐Ÿ“ Aurora University of Colorado, Denver ยท Tests: Paclitaxel, NALIRIFOX Maintenance Niraparib Plus Ipilimumab in Patients With Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on Platinum-Based Chemotherapy NCT06747845Phase 22 sites๐Ÿ“ Boston๐Ÿ“ Philadelphia Abramson Cancer Center at Penn Medicine ยท Tests: Niraparib, FOLFIRI, Ipilimumab Study of MT-302 in Adults With Advanced or Metastatic Epithelial Tumors NCT05969041Phase 16 sites๐Ÿ“ Darlinghurst๐Ÿ“ Randwick๐Ÿ“ Westmead Myeloid Therapeutics ยท Tests: MT-302 (A) Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC-6236) Versus Gemcitabine and Nab-Paclitaxel as First-Line Treatment in Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma NCT07805954Phase 35 sites๐Ÿ“ Phoenix๐Ÿ“ Scottsdale๐Ÿ“ Jacksonville Revolution Medicines, Inc. ยท Tests: daraxonrasib, gemcitabine, nab-paclitaxel, zoldonrasib Advanced Therapies for Liver Metastases NCT04622423n/a1 site๐Ÿ“ Milan IRCCS San Raffaele Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer NCT05254171Phase 2, Phase 393 sites๐Ÿ“ Hot Springs๐Ÿ“ Fullerton๐Ÿ“ New Haven Panbela Therapeutics, Inc. ยท Tests: SBP-101, Nab-paclitaxel, Gemcitabine, Placebo Cemiplimab Plus Gemcitabine in Patients With Metastatic Pancreatic Adenocarcinoma NCT06790602Phase 21 site๐Ÿ“ La Jolla University of California, San Diego ยท Tests: Cemiplimab Plus Gemcitabine A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer NCT07644559Phase 238 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Verastem, Inc. ยท Tests: VS-7375, cetuximab (or panitumumab if ฮฑ-gal IgE+ or cetuximab reaction) A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue NCT06989437Phase 2, Phase 3230 sites๐Ÿ“ Birmingham๐Ÿ“ Birmingham๐Ÿ“ Phoenix Pfizer ยท Tests: ponsegromab, placebo A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer NCT07049055Phase 1, Phase 24 sites๐Ÿ“ El Segundo๐Ÿ“ Summit๐Ÿ“ New York Engeneic Pty Limited ยท Tests: E-EDV-D682, EDV-GC, Gemcitabine, Nab paclitaxel. Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors NCT06040541Phase 117 sites๐Ÿ“ Sacramento๐Ÿ“ New Haven๐Ÿ“ Sarasota Revolution Medicines, Inc. ยท Tests: RMC-9805, RMC-6236 Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS NCT05379985Phase 1, Phase 221 sites๐Ÿ“ Orange๐Ÿ“ Santa Monica๐Ÿ“ Tampa Revolution Medicines, Inc. ยท Tests: RMC-6236 A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors NCT04657068Phase 1, Phase 288 sites๐Ÿ“ Birmingham๐Ÿ“ Scottsdale๐Ÿ“ Little Rock Artios Pharma Ltd ยท Tests: ART0380, Gemcitabine, Irinotecan A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma NCT07490301Phase 2, Phase 322 sites๐Ÿ“ New Haven๐Ÿ“ Chicago๐Ÿ“ Zion AbbVie ยท Tests: Telisotuzumab adizutecan, Fluorouracil, Folinic acid/ Leucovorina, Oxaliplatin, Irinotecan iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation NCT03608631Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Mesenchymal Stromal Cells-derived Exosomes with KRAS G12D siRNA A Study Evaluating the Efficacy of 5-FU + NALIRI and 5-FU + NALIRINOX for PDAC (NALPAC) NCT05472259Phase 213 sites๐Ÿ“ Antwerp๐Ÿ“ Brussels๐Ÿ“ Brussels Belgian Group of Digestive Oncology ยท Tests: Nanoliposomal irinotecan, 5 FU, Leucovorin, Oxaliplatin A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors NCT07094204Phase 120 sites๐Ÿ“ Santa Monica๐Ÿ“ Atlanta๐Ÿ“ Jefferson Astellas Pharma Inc ยท Tests: ASP5834, panitumumab A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations NCT06835569Phase 114 sites๐Ÿ“ Orlando๐Ÿ“ Tampa๐Ÿ“ Boston Alterome Therapeutics, Inc. ยท Tests: ALTA3263, cetuximab, mFOLFOX6, Pembrolizumab, Pemetrexed + Cisplatin /Carboplatin Relacorilant With Nab-Paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Adenocarcinoma NCT07259317Phase 220 sites๐Ÿ“ Scottsdale๐Ÿ“ Los Angeles๐Ÿ“ Orange Corcept Therapeutics ยท Tests: Relacorilant, Nab-paclitaxel, Gemcitabine A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations NCT07629960Phase 1, Phase 216 sites๐Ÿ“ Sarasota๐Ÿ“ Tampa๐Ÿ“ Baton Rouge Blueprint Medicines Corporation ยท Tests: BLU-924 A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer NCT07227168Phase 19 sites๐Ÿ“ San Diego๐Ÿ“ Denver๐Ÿ“ Washington D.C. Sutro Biopharma, Inc. ยท Tests: STRO-004, Pembrolizumab Monthly Alternating NALIRIFOX and GnP in the First-Line Setting for Metastatic Pancreatic Ductal Adenocarcinoma NCT07163273Phase 27 sites๐Ÿ“ Bay Shore๐Ÿ“ Mount Kisco๐Ÿ“ New Hyde Park Northwell Health ยท Tests: NALIRIFOX, Gemcitabine plus nab-Paclitaxel (GnP) OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma NCT07089940EARLY Phase 11 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Myc Inhibitor OMO-103 Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma NCT07214298Phase 1, Phase 21 site๐Ÿ“ Buffalo Roswell Park Cancer Institute ยท Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Fluorouracil, Irinotecan NALIRIFOX+Adebrelimab+PULSAR for Advanced Pancreatic Cancer NCT07595172Phase 1, Phase 21 site๐Ÿ“ Chengdu West China Hospital ยท Tests: NALIRIFOX+Adebrelimab, PULSAR
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