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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Metastatic Prostate Adenocarcinoma

PRO-BOOST-LC: Whole-Gland Boost Strategies Versus SBRT Monotherapy in PSMA-Staged Localized and Locally Advanced Prostate Cancer NCT07426055Phase 2, Phase 31 site๐Ÿ“ Zamoล›ฤ‡ Affidea Nu-med Center of Oncological DIagnostics and Therapy ยท Tests: Stereotactic Body Radiotherapy (SBRT) Monotherapy, External Beam Radiotherapy (EBRT) Backbone, High-Dose-Rate Brachytheโ€ฆ A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer NCT06067841Phase 115 sites๐Ÿ“ Palo Alto๐Ÿ“ Sarasota๐Ÿ“ Boston Bristol-Myers Squibb ยท Tests: BMS-986460 Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response NCT06592924Phase 3395 sites๐Ÿ“ Anchorage๐Ÿ“ Anchorage๐Ÿ“ Anchorage Canadian Cancer Trials Group ยท Tests: Abiraterone, Enzalutamide, Apalutamide, Darolutamide (BAY 1841788), Docetaxel PSMA PET for Surveillance After Focal Therapy NCT07115914NA1 site๐Ÿ“ Chicago University of Chicago ยท Tests: PSMA PET/CT scan Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer NCT06145633Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Biopsy Procedure, Biospecimen Collection, Bone Scan, Computed Tomography, Fludeoxyglucose F-18 Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer NCT07667400Phase 1, Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: SX-682, DTX Study of DCC-2812 in Participants With Advanced Genitourinary Cancers NCT06966024Phase 18 sites๐Ÿ“ Boston๐Ÿ“ Ann Arbor๐Ÿ“ St Louis Deciphera Pharmaceuticals, LLC ยท Tests: DCC-2812 Kuopio Lutetium-177 Study in Patients with PSMA-Positive Metastatic Prostate Cancer NCT06850545n/a1 site๐Ÿ“ Kuopio Kuopio University Hospital IDOV-Immune for Advanced Solid Tumors NCT06910657Phase 15 sites๐Ÿ“ St Louis๐Ÿ“ Houston๐Ÿ“ San Antonio ViroMissile, Inc. ยท Tests: IDOV-Immune (oncolytic vaccinia virus) A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation NCT06778863Phase 121 sites๐Ÿ“ Scottsdale๐Ÿ“ Tucson๐Ÿ“ Los Angeles Clasp Therapeutics, Inc. ยท Tests: CLSP-1025 ABlative Radiotherapy (for) Unfavorable Prostate Tumors 2.0 NCT07407608n/a1 site๐Ÿ“ Monza University of Milano Bicocca ยท Tests: SBRT, SDRT REGN15505 (PSMAx4-1BB) Alone or in Combination With Cemiplimab or REGN4336 (PSMAxCD3) in Adult Patients With Metastatic Castration-Resistant Prostate Cancer and Clear Cell Renal Cell Carcinoma NCT07594106Phase 1, Phase 26 sites๐Ÿ“ Goodyear๐Ÿ“ Duarte๐Ÿ“ Tampa Regeneron Pharmaceuticals ยท Tests: REGN15505, REGN15505+Cemiplimab, REGN15505+REGN4336 Estrogen to Improve Quality of Life for Men With Newly Diagnosed or Recurrent Metastatic Hormone Sensitive Prostate Cancer, EQUIP Trial NCT07466498Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Androgen Receptor Pathway Inhibitor, Transdermal Estrogen, Bone Scan, Computed Tomography, Dual X-ray Absorptiometry Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging NCT04423211Phase 3341 sites๐Ÿ“ Anchorage๐Ÿ“ Anchorage๐Ÿ“ Anchorage ECOG-ACRIN Cancer Research Group ยท Tests: 3-Dimensional Conformal Radiation Therapy, Apalutamide, Computed Tomography, Degarelix, External Beam Radiation Therapy A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors NCT03972657Phase 1, Phase 224 sites๐Ÿ“ Gilbert๐Ÿ“ Phoenix๐Ÿ“ Tucson Regeneron Pharmaceuticals ยท Tests: REGN5678, Cemiplimab Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study NCT06039371Phase 21 site๐Ÿ“ Seattle University of Washington ยท Tests: Biopsy Procedure, Biospecimen Collection, Bone Scan, Carboplatin, Computed Tomography Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial NCT06931340Phase 3213 sites๐Ÿ“ Tucson๐Ÿ“ Tucson๐Ÿ“ Dublin Alliance for Clinical Trials in Oncology ยท Tests: Androgen Therapy, Apalutamide, Docetaxel, Computed Tomography, Magnetic Resonance Imaging Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer NCT05113537Phase 1, Phase 21 site๐Ÿ“ San Francisco Vadim S Koshkin ยท Tests: Abemaciclib, Lutetium Lu 177-PSMA-617 Clinical, Genetic and Environmental Determinants of Prostate Cancer Progression. NCT06046131NA2 sites๐Ÿ“ Rennes๐Ÿ“ Pointe-ร -Pitre Centre Hospitalier Universitaire de la Guadeloupe ยท Tests: Standard care Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors NCT07523529Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: Autologous dual-target CAR-T cells selected from the predefined target library., Fludarabine, Cyclophosphamide Measuring Oncological Value of Exercise and Statin NCT05796973Phase 31 site๐Ÿ“ Tampere Tampere University Hospital ยท Tests: Guided physical exercise, Atorvastatin, Independent exercise Phase I Study of Docetaxel and 177-Lutetium-PSMA-I&T in First-Line Treatment for Patients With Metastatic Castration-Resistant Prostate Adenocarcinoma NCT07316686Phase 11 site๐Ÿ“ Sรฃo Paulo Instituto do Cancer do Estado de Sรฃo Paulo ยท Tests: Docetaxel 50mg/m2, Docetaxel 60mg/m2, Docetaxel 75 mg/mยฒ, 177Lu-PSMA-I&T Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells NCT05691465Phase 213 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Computed Tomography, Gallium Ga 68-DOTATATE, Lutetium Lu 177 Dotatate, Positron Emission Tomogrโ€ฆ Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial NCT07650240Phase 21 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Abiraterone Acetate, Biospecimen Collection, Leuprolide Acetate, Lutetium Lu 177 Vipivotide Tetraxetan, Prednisone Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma NCT06582017Phase 111 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Nammi Therapeutics Inc ยท Tests: QXL138AM Injection every 2 weeks by IV Infusion Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer NCT03678025Phase 3338 sites๐Ÿ“ Gilbert๐Ÿ“ Phoenix๐Ÿ“ Phoenix SWOG Cancer Research Network ยท Tests: Abiraterone, Bicalutamide, Degarelix, Docetaxel, Flutamide A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors NCT05914116Phase 1, Phase 2107 sites๐Ÿ“ Tucson๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles DualityBio Inc. ยท Tests: DB-1311, Lopinavir and Ritonavir Tablets, itraconazole, Enzalutamide, Abiraterone FOG-001 in Locally Advanced or Metastatic Solid Tumors NCT05919264Phase 1, Phase 233 sites๐Ÿ“ Phoenix๐Ÿ“ Scottsdale๐Ÿ“ Tucson Parabilis Medicines, Inc. ยท Tests: FOG-001, mFOLFOX-6, Nivolumab, Trifluridine/tipiracil, Bevacizumab A Study of MGC026 in Participants With Advanced Solid Tumors NCT06242470Phase 112 sites๐Ÿ“ Los Angeles๐Ÿ“ Grand Rapids๐Ÿ“ Lake Success MacroGenics ยท Tests: MGC026 Dose Escalation, MGC026 Dose for Expansion Imaging of Solid Tumors Using 18F-TRX NCT06942104Phase 11 site๐Ÿ“ San Francisco Rahul Aggarwal ยท Tests: 18F-TRX, Positron Emission Tomography (PET)/Computerized tomography (CT), Tumor Biopsy, Blood Specimen Collection
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