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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Multiple Myeloma, Smoldering

Promoting Diagnosis and Management of AL in Italy (ProDigALIty) NCT06383143n/a4 sites๐Ÿ“ Bari๐Ÿ“ Catania๐Ÿ“ Pavia Fondazione IRCCS Policlinico San Matteo di Pavia ยท Tests: no intervention Smoldering Myeloma High-Risk Patient Observation and Longitudinal Insight Trial NCT06212323n/a1 site๐Ÿ“ Salt Lake City University of Utah ยท Tests: Patients with smoldering myeloma undergoing active surveillance with diffusion weighted whole body MRI. FAST-M: Prolonged Overnight Fasting and Mediterranean Dietary Intervention for Patients With Multiple Myeloma or Its Precursor Disease NCT07446777NA1 site๐Ÿ“ Miami University of Miami ยท Tests: Health Coaching, Prolonged Overnight Fasting (POF), Mediterranean Diet, Supportive Materials Screening for AL Amyloidosis in Smoldering Multiple Myeloma NCT06365060n/a13 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ San Francisco Tufts Medical Center A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma NCT06140524Phase 239 sites๐Ÿ“ Baltimore๐Ÿ“ Boston๐Ÿ“ Ann Arbor Regeneron Pharmaceuticals ยท Tests: Linvoseltamab A Cohort Study of Plasma Cell Disorders (PCDs) in PKUFH NCT05283993n/a1 site๐Ÿ“ Beijing Peking University First Hospital ยท Tests: No intervention The TG01 Study With TG01/QS-21 Vaccine in Patients With High-risk Smouldering Multiple Myeloma and Multiple Myeloma NCT05841550Phase 1, Phase 21 site๐Ÿ“ Oslo Oslo University Hospital ยท Tests: TG01 A Phase 1 With Extension Cohort, Single Arm, Single Center, Open Label Trial of Belantamab Mafodotin for the Treatment of High-Risk Smoldering Multiple Myeloma NCT05055063Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Belantamab mafodotin Non-chemotherapeutic Interventions for the Improvement of Quality of Life and Immune Function in Patients With Multiple Myeloma NCT05312255NA1 site๐Ÿ“ Buffalo Roswell Park Cancer Institute ยท Tests: Behavioral Intervention, Beta-Adrenergic Antagonist, Propranolol, Quality-of-Life Assessment, Questionnaire Administratโ€ฆ Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma NCT03937635Phase 3748 sites๐Ÿ“ Birmingham๐Ÿ“ Anchorage๐Ÿ“ Anchorage ECOG-ACRIN Cancer Research Group ยท Tests: Daratumumab, Dexamethasone, Lenalidomide, Quality-of-Life Assessment, Questionnaire Administration Whole Body MRI in Oncology NCT06895291n/a3 sites๐Ÿ“ Bologna๐Ÿ“ Meldola๐Ÿ“ Milan Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRโ€ฆ ยท Tests: Whole Body-Magnetic Resonance Imaging (WB-MRI) Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple Myeloma NCT04776395Phase 21 site๐Ÿ“ Atlanta Emory University ยท Tests: Dexamethasone, Iberdomide Hydrochloride, Quality-of-Life Assessment CHAAMP (CHArlotte Advocate MGUS Project) Internal Pilot Study NCT06644625n/a1 site๐Ÿ“ Charlotte Wake Forest University Health Sciences ยท Tests: Blood draw for the laboratory assessment A Study to Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering Multiple Myeloma (HR-SMM) NCT07393282Phase 327 sites๐Ÿ“ Phoenix๐Ÿ“ Atlanta๐Ÿ“ Boston Regeneron Pharmaceuticals ยท Tests: Linvoseltamab, Daratumumab Immuno-PRISM (PRecision Intervention Smoldering Myeloma) NCT05469893Phase 23 sites๐Ÿ“ Denver๐Ÿ“ Boston๐Ÿ“ Portland Irene Ghobrial, MD ยท Tests: Teclistamab, Lenalidomide, Dexamethasone A Prospective Multicenter Study of the Effects of Plant-based Diets on Gut Microbiome and Derived Metabolites in Patients Affected by Smoldering Multiple Myeloma NCT07069751NA5 sites๐Ÿ“ Milan๐Ÿ“ Bari๐Ÿ“ Milan Ciceri Fabio ยท Tests: diet rich in fiber Two Biologically and Clinically Distinct Entities: Progressive Versus Stable Multiple Myeloma (MM) Precursor Conditions NCT05361694n/a1 site๐Ÿ“ Miami University of Miami A Study of a Plant-Based Diet and Dietary Supplements in People With Smoldering Multiple Myeloma (SMM) or Monoclonal Gammopathy of Undetermined Significance (MGUS) NCT06055894NA7 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: Omega-3, Curcumin, Probiotic, Whole food, plant-based diet (WFPBD) A Study of JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide for Multiple Myeloma, Newly Diagnosed AL Amyloidosis, and High-risk Smoldering Multiple Myeloma or JNJ-79635322 in Combination With Pomalidomide for Multiple Myeloma NCT06768489Phase 116 sites๐Ÿ“ Denver๐Ÿ“ Atlanta๐Ÿ“ Clayton Janssen Research & Development, LLC ยท Tests: JNJ-79635322, Daratumumab, Pomalidomide, Lenalidomide BCMA/CD3 BsAb in the Treatment of High-risk Smoldering Multiple Myeloma NCT06745687NA1 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: CM336 Selinexor for the Treatment of Intermediate and High-Risk Smoldering Multiple Myeloma NCT05597345Phase 21 site๐Ÿ“ Rochester University of Rochester ยท Tests: Selinexor Observational Prospective Research Study In Monoclonal Gammopathies leadINg to Myeloma NCT02726750n/a1 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Biospecimen Collection, Laboratory Biomarker Analysis Quality of Life in Patients With Asymptomatic Monoclonal Gammopathies NCT05136807n/a1 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Quality-of-Life Assessment, Questionnaire Administration Integrative Multi-omics Analysis to Predict Monoclonal Gammopathies Clinical Evolution NCT07214324n/a4 sites๐Ÿ“ Bologna๐Ÿ“ Catania๐Ÿ“ Palermo Azienda USL Reggio Emilia - IRCCS ยท Tests: Collection of biological material Registry for Adults With Plasma Cell Disorders (PCD's) NCT03717844n/a1 site๐Ÿ“ Chapel Hill UNC Lineberger Comprehensive Cancer Center Isatuximab and Iberdomide as Immunotherapy for High Risk in Smouldering Myeloma NCT06762769Phase 214 sites๐Ÿ“ Leeds๐Ÿ“ Oxford๐Ÿ“ Aberdeen University College, London ยท Tests: Isatuximab, Iberdomide, Dexamethasone The Indiana Myeloma Registry NCT03616483n/a1 site๐Ÿ“ Indianapolis Indiana University ยท Tests: This is a non-interventional trial Ciltacabtagene Autoleucel in High-Risk Smoldering Multiple Myeloma NCT06574126Phase 21 site๐Ÿ“ Salamanca PETHEMA Foundation ยท Tests: Group 1: Dara-VRD followed by apheresis and cilta-cel infusion, Group 2: Apheresis followed by Dara-VRD and cilta-cel iโ€ฆ Teclistamab in Combination With Daratumumab for High-Risk Smoldering Myeloma: A Clinical and Correlative Phase 2 Immuno-Oncology Study (the REVIVE Study) NCT06100237Phase 21 site๐Ÿ“ Miami Carl Ola Landgren, MD, PhD ยท Tests: Teclistamab, Talquetamab, Daratumumab SC Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome NCT02269592n/a7 sites๐Ÿ“ Boston๐Ÿ“ Brighton๐Ÿ“ Methuen Dana-Farber Cancer Institute
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