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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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27 recruiting trials

for Myelofibrosis๏ผŒMF

Evaluating Safety ,Tolerability, Pharmacokinetic,Efficacy of WJ01024 or WJ01024 Combined With Ruxolitinib in Patients With Myelofibrosis NCT07802405Phase 11 site๐Ÿ“ Zhengzhou Henan Cancer Hospital ยท Tests: WJ01024 tablet Combination of Tagraxofusp With Pacritinib in Patients With Intermediate-1 or Higher Myelofibrosis, Who Have Had Prior Therapy With the Approved JAK Inhibitors or in Which Therapy With the Approved JAK Inhibitors is Not Appropriate, Contraindicated or Declined NCT06414681EARLY Phase 11 site๐Ÿ“ Fairway University of Kansas Medical Center ยท Tests: Tagraxofusp, Pacritinib A Clinical Trial of Flonoltinib Maleate for Intermediate or High-Risk Myelofibrosis NCT07317700Phase 32 sites๐Ÿ“ Chengdu๐Ÿ“ Tianjin Chengdu Zenitar Biomedical Technology Co., Ltd ยท Tests: Flonoltinib 75mg, Ruxolitinib Phosphate Pacritinib For Bone Marrow Fibrosis In Patients With Myelofibrosis Who Have Thrombocytopenia NCT07394153Phase 213 sites๐Ÿ“ Barcelona๐Ÿ“ Barcelona๐Ÿ“ Barcelona Grupo Espaรฑol de Enfermedades Mieloproliferativas Crรณnicas โ€ฆ ยท Tests: Pacritinib Open Label Phase 1/2 Study of Tasquinimod in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (Post-PV MF), or Post-Essential Thrombocytosis Myelofibrosis (Post-ET MF) NCT06327100Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Ruxolitinib, Tasquinimod TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT NCT07302776Phase 11 site๐Ÿ“ Palo Alto Stanford University ยท Tests: Tacrolimus, Early Tacrolimus Taper Strategy A New Diagnostic Algorithm to Non-invasively Track Fibrotic Changes in Myeloproliferative Neoplasms Based on C-C Chemokine Receptor 2 Detection. From Flow Cytometry to the Development of Targeted Positron Emission Tomography Molecular Imaging. Pre-clinical Studies and First In-human Proof of Concept NCT07419178NA1 site๐Ÿ“ Parma Azienda Ospedaliero-Universitaria di Parma ยท Tests: Diagnosis of MPN subtypes Ropeginterferon Alfa 2b Plus Ruxolitinib for Myelofibrosis NCT06770842Phase 21 site๐Ÿ“ Hong Kong The University of Hong Kong ยท Tests: Ropeginterferon alfa-2b (BESREMiยฎ) Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120) NCT05835466Phase 29 sites๐Ÿ“ Tampa๐Ÿ“ Atlanta๐Ÿ“ Buffalo Icahn School of Medicine at Mount Sinai ยท Tests: reparixin A Phase 1 Study of LY5830966 in Participants With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i) NCT06343805Phase 121 sites๐Ÿ“ Palo Alto๐Ÿ“ Tampa๐Ÿ“ Kansas City Ajax Therapeutics, Inc., a wholly owned subsidiary of Eli Lโ€ฆ ยท Tests: LY5830966 Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naรฏve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib NCT06479135Phase 3215 sites๐Ÿ“ Birmingham๐Ÿ“ Gilbert๐Ÿ“ Phoenix Kartos Therapeutics, Inc. ยท Tests: Navtemadlin, Navtemadlin placebo, Ruxolitinib Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia NCT05320198Phase 1, Phase 235 sites๐Ÿ“ Gilbert๐Ÿ“ Duarte๐Ÿ“ Irvine Disc Medicine, Inc ยท Tests: DISC-0974 MethoTRExATE in MyelOpRolifErative Neoplasms (TREATMORE) Trial NCT06541249Phase 21 site๐Ÿ“ New York Icahn School of Medicine at Mount Sinai ยท Tests: Methotrexate (MTX) MPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People With Myeloproliferative Neoplasms (MPNs) NCT07362225n/a2 sites๐Ÿ“ Chicago๐Ÿ“ New York MPN Research Foundation Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naรฏve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib NCT05280509Phase 1, Phase 219 sites๐Ÿ“ Birmingham๐Ÿ“ Canton๐Ÿ“ Cincinnati Telios Pharma, Inc. ยท Tests: TL-895, Ruxolitinib A Study of Roginolisib in Combination With Ruxolitinib in Patients With Myelofibrosis (MF) Who Are Unresponsive to JAK Inhibitors NCT06887803Phase 1, Phase 212 sites๐Ÿ“ Florence๐Ÿ“ Rozzano๐Ÿ“ Bologna iOnctura ยท Tests: Roginolisib MPNdpoint. Single-center, Retrospective, Prospective Study of the Outcome of Patients With Philadelphia-negative Chronic Myeloproliferative Neoplasms NCT07863466n/a1 site๐Ÿ“ Milan Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF) NCT06834282Phase 15 sites๐Ÿ“ Sacramento๐Ÿ“ Denver๐Ÿ“ Nashville CERo Therapeutics Holdings, Inc. ยท Tests: CER-1236, Cyclophosphamide, Fludarabine, Mesna A Clinical Trial of Flonoltinib Maleate Tablets in the Treatment of JAK Inhibitor Refractory/Relapsed/Intolerant Patients With Intermediate to High Risk Myelofibrosis NCT07443306Phase 22 sites๐Ÿ“ Chengdu๐Ÿ“ Tianjin Chengdu Zenitar Biomedical Technology Co., Ltd ยท Tests: Flonoltinib Maleate Pacritinib Effectiveness in Real-world Settings NCT07774455n/a5 sites๐Ÿ“ New Haven๐Ÿ“ Tampa๐Ÿ“ Columbus Swedish Orphan Biovitrum ยท Tests: Not applicable- observational study A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF) NCT07357727Phase 3148 sites๐Ÿ“ Denver๐Ÿ“ New Haven๐Ÿ“ Fort Myers Novartis Pharmaceuticals ยท Tests: Pelabresib, Ruxolitinib, Placebo Phase I/II Clinical Trial of Axatilimab, a CSF1R Monoclonal Antibody, in Combination With Ruxolitinib as Therapy for Patients With Myelofibrosis (MF) and Chronic Myelomonocytic Leukemia (CMML) NCT07128381Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Axatilimab (SNDX-6352), Ruxolitinib A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms NCT07469891Phase 118 sites๐Ÿ“ Los Angeles๐Ÿ“ Denver๐Ÿ“ Coral Springs Prelude Therapeutics Incorporated ยท Tests: PRT12396 Haplo-HSCT for Myelofibrosis NCT06674382NA1 site๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: Haploidentical hematopoietic stem cell transplantation A Clinical Trial of TQ05105 Tablets Combined With TQB3617 Capsules in the Treatment of Myelofibrosis (MF) NCT06122831Phase 1, Phase 222 sites๐Ÿ“ Guangzhou๐Ÿ“ Nanning๐Ÿ“ Cangzhou Chia Tai Tianqing Pharmaceutical Group Co., Ltd. ยท Tests: TQ05105 Tablets, TQB3617 Capsules Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL. NCT04771572Phase 18 sites๐Ÿ“ Chicago๐Ÿ“ Boston๐Ÿ“ Chapel Hill Newave Pharmaceutical Inc ยท Tests: LP-118 A Study of Rebecsinib for Patients With Relapsed/Refractory Secondary Acute Myeloid Leukemia or High Risk Myelofibrosis NCT07250646Phase 13 sites๐Ÿ“ Duarte๐Ÿ“ Sacramento๐Ÿ“ San Diego Aspera Biomedicines, Inc. ยท Tests: rebecsinib
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