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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Myeloproliferative Neoplasms

Chemogenomic Profiling in Hematological Malignancies (HEM-Profiling 2021) NCT07445984NA1 site๐Ÿ“ Parma Azienda Ospedaliero-Universitaria di Parma ยท Tests: Genetic, molecular and/or omics analyses Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse NCT06928662Phase 1, Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Decitabine, Bone Marrow Aspiration, Bone Marrow Biopsy, Chest Radiography, Cytarabine A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia. NCT06566742Phase 22 sites๐Ÿ“ Miami๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Olutasidenib Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial NCT06355583Phase 28 sites๐Ÿ“ Birmingham๐Ÿ“ Leeds๐Ÿ“ London Imperial College London ยท Tests: EBX-102, Placebo Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms NCT06063486Phase 22 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles University of Southern California ยท Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Curcumin/ Demethoxycurcumin/Bisdemethoxycurcumin-coโ€ฆ Venetoclax in Addition to Sequential Conditioning With Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for Allogeneic Blood Stem Cell Transplantation in Patients With MDS, CMML or sAML NCT05807932Phase 1, Phase 26 sites๐Ÿ“ Aachen๐Ÿ“ Dรผsseldorf๐Ÿ“ Cologne Heinrich-Heine University, Duesseldorf ยท Tests: Venetoclax, Amsacrine, Ara-C, Tacrolimus, Mycophenolate Mofetil Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant NCT06315309Phase 21 site๐Ÿ“ Birmingham University of Alabama at Birmingham ยท Tests: ATG Combined with Tacrolimus and Mini Methotrexate Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant NCT06543381Phase 12 sites๐Ÿ“ Duarte๐Ÿ“ Cleveland City of Hope Medical Center ยท Tests: Biospecimen Collection, Olutasidenib IMM01+Azacitidine VS Placebo +Azacitidine in Patients With Newly Diagnosed Chronic Myelomonocytic Leukemia (CMML1-2) NCT06647862Phase 343 sites๐Ÿ“ Hefei๐Ÿ“ Beijing๐Ÿ“ Chongqing ImmuneOnco Biopharmaceuticals (Shanghai) Inc. ยท Tests: IMM01, Azacitidine, Placebo Asian Myeloproliferative Neoplasm (MPN) Registry NCT05882773n/a1 site๐Ÿ“ Hong Kong The University of Hong Kong Q702 for the Treatment of Patients With Hematologic Malignancies NCT06712810Phase 12 sites๐Ÿ“ Scottsdale๐Ÿ“ Rochester Mayo Clinic ยท Tests: Axl/Mer/CSF1R Inhibitor Q702, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia NCT03896269Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Liposome-encapsulated Daunorubicin-Cytarabine Study of INCA036978 in Participants With Myeloproliferative Neoplasms NCT07441694Phase 154 sites๐Ÿ“ Birmingham๐Ÿ“ Irvine๐Ÿ“ Los Angeles Incyte Corporation ยท Tests: INCA036978, Standard disease-directed therapy Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia NCT03263572Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Blinatumomab, Cytarabine, Methotrexate, Ponatinib MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia Vera NCT04116502Phase 355 sites๐Ÿ“ Aberdeen๐Ÿ“ Bath๐Ÿ“ Belfast University of Birmingham ยท Tests: Ruxolitinib, Hydroxycarbamide, Interferon-Alpha To Evaluate the Pharmacokinetics and Safety of TQ05105 Tablet in Hepatic Impairment Subjects NCT07480824Phase 12 sites๐Ÿ“ Luoyang๐Ÿ“ Jinan Chia Tai Tianqing Pharmaceutical Group Co., Ltd. ยท Tests: TQ05105 Allo HSCT Using RIC and PTCy for Hematological Diseases NCT05805605Phase 21 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: Peripheral Blood Stem Cell Transplant, Allopurinol 300 MG, Fludarabine, Cyclophosphamide, Bone Marrow Cell Transplant The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen NCT01890486n/a1 site๐Ÿ“ Winston-Salem Wake Forest University Health Sciences Combination of Tagraxofusp With Pacritinib in Patients With Intermediate-1 or Higher Myelofibrosis, Who Have Had Prior Therapy With the Approved JAK Inhibitors or in Which Therapy With the Approved JAK Inhibitors is Not Appropriate, Contraindicated or Declined NCT06414681EARLY Phase 11 site๐Ÿ“ Fairway University of Kansas Medical Center ยท Tests: Tagraxofusp, Pacritinib Research Platform Myelofibrosis and Anemia NCT06976918n/a1 site๐Ÿ“ Multiple Locations iOMEDICO AG A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia NCT05849662Phase 1, Phase 221 sites๐Ÿ“ Phoenix๐Ÿ“ Los Angeles๐Ÿ“ San Francisco Therapeutic Advances in Childhood Leukemia Consortium ยท Tests: Trametinib, Azacitidine, Fludarabine, Cytarabine Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies NCT06904066Phase 11 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: aldesleukin, cyclophosphamide, fludarabine phosphate, Individual Patient TCR-Transduced PBL, TruSight Oncology (TSO) 500 Role of Mesenchymal Stromal Cell Derived Extracellular Vesicles of Primary Myelofibrosis Patients on CD34+ Cells NCT06896344n/a1 site๐Ÿ“ Pavia Fondazione IRCCS Policlinico San Matteo di Pavia ยท Tests: In vitro culture A Clinical Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of TQ05105 Tablets in Subjects With Intermediate/High-risk Myelofibrosis NCT07551427Phase 224 sites๐Ÿ“ Hefei๐Ÿ“ Fuzhou๐Ÿ“ Guangzhou Chia Tai Tianqing Pharmaceutical Group Co., Ltd. ยท Tests: TQ05105 Tablets (Rovadicitinib Tablets) Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS NCT04708054Phase 2, Phase 31 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Busulfan, Cladribine, Fludarabine Phosphate, Hematopoietic Cell Transplantation, Thiotepa Unrelated Umbilical Cord Blood Stem Cell Combined With Azacitidine Based Treatment for Advanced MDS,CMML-2 and sAML NCT05584761Phase 1, Phase 21 site๐Ÿ“ Nanjing The First Affiliated Hospital with Nanjing Medical Universiโ€ฆ ยท Tests: unrelated umbilical cord blood CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRฮฑฮฒ/CD19 Depleted HSCT NCT03810196NA1 site๐Ÿ“ Philadelphia Children's Hospital of Philadelphia ยท Tests: CliniMACS Cell Processing System for TCRฮฑฮฒ + T Cell and CD45RA Depleted Peripheral Stem Cell Addback 18F-FAPI PET/MRI Imaging in Myelofibrosis: a Prospective Observational Study. NCT06164561n/a1 site๐Ÿ“ Hangzhou First Affiliated Hospital of Zhejiang University Myeloproliferative Neoplasms (MPNs) Patient Registry NCT02760238n/a1 site๐Ÿ“ Toronto University Health Network, Toronto ยท Tests: Observational Clinical Study of Azacitidine Combined With Ruxolitinib in the Treatment of Higher-risk MDS/MPN NCT05817955Phase 21 site๐Ÿ“ Nanjing The First Affiliated Hospital with Nanjing Medical Universiโ€ฆ ยท Tests: Azacitidine (AZA) with Ruxolitinib
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