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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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24 recruiting trials

for Newly Diagnosed Diffuse Large B-cell Lymphoma

Zanubrutinib Combined With R-CHOP in the Treatment of Newly Diagnosed DLBCL With p53 Protein Expression NCT06005870Phase 21 site📍 Wuhan Huazhong University of Science and Technology · Tests: Zanubrutinib plus RCHOP R-CDOP Regimen in the Treatment of Newly Diagnosed Non-Hodgkin's Lymphoma With High Tumor Burden NCT05040555NA1 site📍 Changchun oubai, MD/PhD · Tests: R-CDOP Chidamide Combination With R-mini CHOP Followed by Chidamide+CD20 Maintenance in Elderly Newly Diagnosed MYC/BCL2+ DLBCL NCT07493148Phase 21 site📍 Changchun Ou Bai, MD/PHD · Tests: Chidamide, Rituximab, Cyclophosphamide, Doxorubicin, Vincristine A Prospective Clinical Study of the Combination Therapy of Obutinib or Decitabine with Rituximab, Cyclophosphamide, and Prednisone for the Primary Treatment of Elderly Patients with Newly Diagnosed Diffuse Large B-cell Lymphoma NCT06683885Phase 1, Phase 21 site📍 Zhengzhou Mingzhi Zhang · Tests: Obutinib or Decitabine, Rituximab, Compound Cyclophosphamide Tablets and Prednisone Orelabrutinib Combined With Standard Immunochemotherapy With or Without Autologous Hematopoietic Stem Cell Transplantation (Auto-HSCT) for Newly Diagnosed Diffuse Large B-cell Lymphoma (DLBCL) NCT07680933Phase 21 site📍 Xuzhou The Affiliated Hospital of Xuzhou Medical University · Tests: Orelabrutinib combined with standard immunochemotherapy with or without auto-HSCT Lenalidomide Combined With G-CHOP in the Treatment of Newly Diagnosed DLBCL With FL NCT06151080Phase 21 site📍 Xiamen The First Affiliated Hospital of Xiamen University · Tests: Lenalidomide combined with G-CHOP (LO CHOP) Chidamide Plus R-CHOP in Newly Diagnosed Double-Expressor Diffuse Large B-Cell Lymphoma With Other Molecular Subtypes NCT06891157Phase 21 site📍 Nanjing The First Affiliated Hospital with Nanjing Medical Universi… · Tests: Chidamide plus R-CHOP A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma NCT04139304EARLY Phase 18 sites📍 Miami📍 Chicago📍 Baltimore AIDS Malignancy Consortium · Tests: Cyclophosphamide, Daratumumab, Doxorubicin, Doxorubicin Hydrochloride, Etoposide Chidamide Maintenance for MRD-Positive Double-Expressor DLBCL in First Complete Remission NCT07507318Phase 21 site📍 Shanghai Rong Tao · Tests: Chidamide HEME-25 Open-Label Feasibility Study of Elranatamab Utilized as Consolidation in Newly Diagnosed Plasmablastic Lymphoma With or Without HIV NCT07647432Phase 11 site📍 Chicago University of Illinois at Chicago · Tests: Elranatamab (Elra) Pola-R2 in Newly Diagnosed Non-fit Elderly DLBCL Patients NCT06176729Phase 21 site📍 Beijing Yan Zhang, MD · Tests: Polatuzumab Vedotin, Rituximab, Lenalidomide Application of Zanubrutinib-based Combination Regimens in the Treatment of Newly-diagnosed Diffuse Large B-cell Lymphoma NCT07371923Phase 21 site📍 Beijing Beijing Tongren Hospital · Tests: Zanubrutinib+Pola-R-CHP Phase 2 Trial of Epcoritamab in Combination With Rituximab-mini CVP for Older Unfit/Frail Patients or Anthracycline-Ineligible Adult Patients With Newly Diagnosed Diffuse Large B-cell Lymphoma NCT06045247Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Prednisone, Rituximab, Cyclophosphamide, Vincristine, Epcoritamab Pomalidomide, Rituximab and Orelabrutinib Combined With Polatuzumab Vedotin in the Treatment of Newly Diagnosed Elderly Patients With DLBCL NCT07072208NA1 site📍 Suzhou The First Affiliated Hospital of Soochow University · Tests: Induction therapy-Pro regimen, Consolidation therapy-Pro-pola regimen Genetic Subtype-matched Targeted Therapy for the Treatment of Newly Diagnosed DLBCL With TP53 Mutation NCT07499271Phase 21 site📍 Suzhou The First Affiliated Hospital of Soochow University · Tests: POLA-R-CHP, Orelabrutinib Hypofractionated Radiotherapy Plus GM-CSF, Pomalidomide and Glofitamab for Newly Diagnosed PCNS-DLBCL NCT07749365Phase 21 site📍 Xiamen The First Affiliated Hospital of Xiamen University · Tests: hypofractionated radiotherapy plus GM-CSF, pomalidomide and glofitamab CHiR Therapy for Elderly DLBCL Intolerant to Chemo NCT06764017Phase 21 site📍 Ningbo First Affiliated Hospital of Ningbo University · Tests: CHiR-DEL Clinical Study of HiR+X Therapy for Newly Diagnosed Elderly Patients With DLBCL Intolerant to Chemotherapy NCT06758037Phase 21 site📍 Ningbo First Affiliated Hospital of Ningbo University · Tests: Drug therapy Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial NCT07220187Phase 362 sites📍 Irvine📍 Laguna Hills📍 Orange SWOG Cancer Research Network · Tests: Biospecimen Collection, Computed Tomography, Cyclophosphamide, Doxorubicin Hydrochloride, Echocardiography Test ctDNA-guided Therapy Optimization in Newly Diagnosed DLBCL NCT06693830NA1 site📍 New York Hua-Jay J Cherng, MD · Tests: Phased Variant Enrichment and Detection Sequencing (PhasED-seq), Standard of Care Treatment, De-escalated Treatment The CARDIOPROTECT Trial NCT07654426Phase 21 site📍 Boston Beth Israel Deaconess Medical Center · Tests: Dexrazoxane, Dexrazoxane placebo, Doxorubicin, Liposomal Doxorubicin, Cyclophosphamide The Safety and Effectiveness of 4R-CHOP+4R vs 6R-CHOP+2R in Newly Diagnosed Patients With DLBCL in Low Risk NCT05018520Phase 31 site📍 Shanghai Ruijin Hospital · Tests: Six Courses of R-CHOP Plus Two Courses of Rituximab, Four Courses of R-CHOP Plus Four Courses of Rituximab R-CMOP in Patients With Newly Diagnosed Diffuse Large B-cell Lymphoma NCT06594640Phase 1, Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Mitoxantrone Hydrochloride Liposome, Rituximab (R), Cyclophosphamide (CTX), Vincristin, Prednisolone Celecoxib Plus R-CHOP vs R-CHOP in Newly Diagnosed Advanced CD5+ DLBCL NCT07494565Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: Celecoxib Combined with R-CHOP, R-CHOP
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