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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Nonsmall Cell Lung Cancer, Stage IV

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC NCT06162221Phase 1, Phase 298 sites๐Ÿ“ Gilbert๐Ÿ“ Duarte๐Ÿ“ Irvine Revolution Medicines, Inc. ยท Tests: RMC-6291, RMC-6236, Pembrolizumab, Cisplatin, Carboplatin ORIENT-31 Regimen in Combination With SBRT for EGFR-mutant Metastatic NSCLC After First-line Third-generation EGFR-TKIs NCT06775743Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: ORIENT-31 regimen, SBRT A Phase I Study of CFT8919 in Patients With Advanced NSCLC NCT06641609Phase 11 site๐Ÿ“ Hangzhou Betta Pharmaceuticals Co., Ltd. ยท Tests: Dose-Escalation (Phase Ia) CFT8919 capsule, Dose-Expansion (Phase Ib) CFT8919 capsule, Cohort-Expansion (Phase Ic) CFT8โ€ฆ A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation. NCT05967689Phase 280 sites๐Ÿ“ Birmingham๐Ÿ“ Duarte๐Ÿ“ Boston Taiho Oncology, Inc. ยท Tests: TAS6417, CYP Cocktail, Transporter Cocktail A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2) NCT06452277Phase 3279 sites๐Ÿ“ Newport Beach๐Ÿ“ San Diego๐Ÿ“ San Francisco Bayer ยท Tests: Sevabertinib, Pembrolizumab, Cisplatin, Carboplatin, Pemetrexed GT103 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic STK11 Mutant Non-Small Cell Lung Cancer NCT07017829Phase 21 site๐Ÿ“ Buffalo Roswell Park Cancer Institute ยท Tests: Anti-CFH Monoclonal Antibody GT103, Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test A Phase Ib Study of GC101 in NSCLC NCT06473961Phase 11 site๐Ÿ“ Shanghai Shanghai Juncell Therapeutics ยท Tests: Autologous Tumor Infiltrating Lymphocytes A Phase 2 Clinical Study of Combination Therapy With ABSK043 and Firmonertinib NCT06668103Phase 25 sites๐Ÿ“ Hefei๐Ÿ“ Harbin๐Ÿ“ Wuhan Abbisko Therapeutics Co, Ltd ยท Tests: ABSK043 in combination with Firmonertinib Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation NCT07012031Phase 1, Phase 29 sites๐Ÿ“ Sacramento๐Ÿ“ Tampa๐Ÿ“ Tampa National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test, Magnetic Resonance Imaging Safety and Efficacy of OBX-115 in Advanced Solid Tumors NCT06060613Phase 1, Phase 210 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Stanford Obsidian Therapeutics, Inc. ยท Tests: OBX-115 Immunonutrition for Improving the Efficacy of Immunotherapy in Patients With Metastatic Non-small Cell Lung Cancer NCT05384873NA1 site๐Ÿ“ Pavia Fondazione IRCCS Policlinico San Matteo di Pavia ยท Tests: Immunonutrition, Control dietary intervention A Study of SHR-A1811 in First-line Treatment of Patients With Advanced or Metastatic Non-small Cell Lung Cancer With HER2 Mutations NCT06430437Phase 31 site๐Ÿ“ Shanghai Jiangsu HengRui Medicine Co., Ltd. ยท Tests: SHR-A1811, PD-1/PD-L1 inhibitorsใ€Pemetrexed/ Paclitaxelใ€Carboplatin/ Cisplatin Vebreltinib Plus Furmonertinib in Patients With EGFR-mutated Advanced Non-small Cell Lung Cancer and High PD-L1 Expression NCT07655622Phase 1, Phase 21 site๐Ÿ“ Nanchang Second Affiliated Hospital of Nanchang University ยท Tests: Vebreltinib, Furmonertinib 80mg A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202) NCT05920356Phase 3424 sites๐Ÿ“ Santa Barbara๐Ÿ“ Newark๐Ÿ“ Coral Springs Amgen ยท Tests: Sotorasib, Pembrolizumab Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial) NCT06116682Phase 2271 sites๐Ÿ“ Jonesboro๐Ÿ“ Little Rock๐Ÿ“ Auburn SWOG Cancer Research Network ยท Tests: Amivantamab, Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study NCT07405086Phase 41 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Biospecimen Collection, Immune Checkpoint Inhibitor A Phase 1b/2 Study of the Safety and Efficacy of the Monoclonal Antibody OM-RCA-01 in Patients With Metastatic Tumors Expressing Fibroblast Growth Factor Receptor 1 NCT07292168Phase 1, Phase 25 sites๐Ÿ“ Kazan'๐Ÿ“ Krasnoyarsk๐Ÿ“ Moscow Kidney Cancer Research Bureau ยท Tests: humanized monoclonal anti-FGFR1 antibody OM-RCA-01 Impact of Respiratory Rehabilitation on Quality of Life in Patients With Metastatic Non-small Cell Lung Cancer Treated With Immunotherapy and Chemotherapy in the Maintenance Phase NCT06441773NA3 sites๐Ÿ“ Brest๐Ÿ“ Morlaix๐Ÿ“ Quimper University Hospital, Brest ยท Tests: Respiratory Rehabilitation Nelmastobart in Combination With Docetaxel in Non Small Cell Lung Cancer NCT07306624Phase 25 sites๐Ÿ“ Gyeonggi-do๐Ÿ“ Seoul๐Ÿ“ Seoul STCube, Inc. ยท Tests: Nelmastobart and Docetaxel Molecularly Targeted Radionuclide Therapy Via the Integrin Alphavbeta6 NCT06228482Phase 11 site๐Ÿ“ Sacramento University of California, Davis ยท Tests: [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G. Magnesium Supplementation in Advanced Non-small Cell Lung Cancer (NSCLC) NCT07149649Phase 2, Phase 311 sites๐Ÿ“ Aarau๐Ÿ“ Aarau๐Ÿ“ Baden Swiss Cancer Institute ยท Tests: Magnesiocard, Magnesium Diasporal, Microcrystalline cellulose, Isotonic saline solution 0.9% Feasibility Study of Tissue and Blood Collection in Oncogene-addicted and Neoadjuvantly Treated Non Small Cell Lung Cancer NCT07008742n/a1 site๐Ÿ“ London Royal Marsden NHS Foundation Trust A Trial of SHR-A2102 With Adebrelimab With or Without Other Antitumor Therapy in Advanced or Metastatic Non-small Cell Lung Cancer NCT06512051Phase 1, Phase 21 site๐Ÿ“ Beijing Shanghai Hengrui Pharmaceutical Co., Ltd. ยท Tests: SHR-A2102 for Injection, Adebrelimab Injection, Cisplatin injection, Carboplatin injection, Bevacizumab Injection A Phase 2 Study of Luvometinib Combined With Anlotinib in KRAS-mutated NSCLC NCT07562581Phase 21 site๐Ÿ“ Shanghai Shanghai Fosun Pharmaceutical Industrial Development Co. Ltโ€ฆ ยท Tests: luvometinib + anlotinib, luvometinib + anlotinib Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer NCT05168566Phase 231 sites๐Ÿ“ Glendale๐Ÿ“ Washington D.C.๐Ÿ“ Athens Teligene US ยท Tests: Sutetinib Maleate Capsule Risk-adapted, Proteomic-guided Systemic Therapy for Previously Untreated Advanced Non-small Cell Lung Cancer NCT07250477Phase 24 sites๐Ÿ“ Chico๐Ÿ“ Marysville๐Ÿ“ Sacramento University of California, Davis ยท Tests: Systemic (ICI)-based therapy informed by the PROphet CB assay and the CARG-TT assessment., Standard of Care Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial NCT07288034Phase 213 sites๐Ÿ“ Goodyear๐Ÿ“ Corona๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Adagrasib, Anti-PD-L1 Monoclonal Antibody, Anti-PD1 Monoclonal Antibody, Bevacizumab, Biopsy Procedure Disitamab Vedotin in Combination with Tislelizumab and Bevacizumab in a Phase II Clinical Study of Locally Advanced or Metastatic Non-small Cell Lung Cancer with HER2 Mutation/amplification/expression NCT06749860Phase 21 site๐Ÿ“ Shanghai Shanghai Pulmonary Hospital, Shanghai, China ยท Tests: Disitamab Vedotin + tislelizumab + bevacizumab Real World Study of Platinum Containing Dual Drug Chemotherapy Followed by Large Fractionated Radiotherapy Combined withTislelizumab in Stage IIIB/C-IV Non-small Cell Lung Cancer Patient NCT07198217Phase 21 site๐Ÿ“ Zibo Zibo Municipal Hospital ยท Tests: SBRT combined with Tislelizumab followed by Tislelizumab Dabrafenib and/or Trametinib Rollover Study NCT03340506Phase 438 sites๐Ÿ“ Scottsdale๐Ÿ“ Bethesda๐Ÿ“ Columbus Novartis Pharmaceuticals ยท Tests: dabrafenib, trametinib
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