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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Pathological Complete Remission

Evaluation of [68Ga]Ga-NOTA-anti-HER2-sdAb PET/CT for Predicting Pathological Complete Response After Neoadjuvant Chemotherapy in HER2 Positive Early Breast Cancer NCT07593976Phase 21 site๐Ÿ“ Rouen Centre Henri Becquerel ยท Tests: [68Ga]Ga-NOTA-anti-HER2-sdAb Positron Emission Tomography Application of MRI Radiomics Features in Neoadjuvant Therapy of Head and Neck Squamous Cell Carcinoma NCT06755567n/a1 site๐Ÿ“ Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University ยท Tests: MRI-based radiomics-clinical model Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients NCT05350722NA7 sites๐Ÿ“ Sydney๐Ÿ“ Almere Stad๐Ÿ“ Amstelveen Amsterdam UMC, location VUmc ยท Tests: Single dose ablative radiotherapy Prospective Validation of Ataraxis AI Test for Predicting Treatment Response in Neoadjuvant Breast Cancer NCT07327970n/a1 site๐Ÿ“ Incheon Young-Joon Kang ยท Tests: multi-modal foundation AI test 40.2Gy Versus 49.2Gy Radiotherapy in Low-Risk Target Volume for Chemosensitive Stage II Nasopharyngeal Carcinoma NCT07328854Phase 315 sites๐Ÿ“ Hefei๐Ÿ“ Fuzhou๐Ÿ“ Guangzhou Ming-Yuan Chen ยท Tests: Cisplatin-based induction chemotherapy, Full course of PD-1 monoclonal antibody, Reduced-dose radiotherapy to CTV2, Conโ€ฆ Comparing Post-Transplant Cyclophosphamide As GVHD Prophylaxis to Standard of Care for Acute Leukemia Patients NCT04314219Phase 31 site๐Ÿ“ Riyadh King Faisal Specialist Hospital & Research Center ยท Tests: Cyclophosphamide 50mg, Methotrexate Watch and Wait as Treatment for Patients With Rectal Cancer NCT03125343NA2 sites๐Ÿ“ Gothenburg๐Ÿ“ Stockholm Sahlgrenska University Hospital ยท Tests: endoscopy, Surgery, MRI Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer NCT06220214EARLY Phase 11 site๐Ÿ“ Stony Brook Alison Stopeck ยท Tests: CEDM, CEDBT, Omnipaque 350mgI/mL Solution for Injection A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019) NCT06312137Phase 3270 sites๐Ÿ“ Little Rock๐Ÿ“ Springdale๐Ÿ“ Beverly Hills Merck Sharp & Dohme LLC ยท Tests: Sacituzumab tirumotecan, Pembrolizumab, Cisplatin, Pemetrexed, Gemcitabine A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer NCT05563766Phase 27 sites๐Ÿ“ Palo Alto๐Ÿ“ Ann Arbor๐Ÿ“ Durham VA Office of Research and Development ยท Tests: Itraconazole Chemoradiation and Consolidation Chemotherapy With or Without Oxaliplatin for Distal Rectal Cancer and Watch and Wait NCT05000697NA24 sites๐Ÿ“ Buenos Aires๐Ÿ“ Buenos Aires๐Ÿ“ Buenos Aires Hospital Alemรฃo Oswaldo Cruz ยท Tests: Oxaliplatin, 5FU Watch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal Cancer NCT04643041NA1 site๐Ÿ“ Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University ยท Tests: watch and wait Refusal of Breast Surgery in Patients With Breast Cancer With a Clinical Complete Response (cCR) After Neoadjuvant Systemic Therapy and a Confirmed Pathological Complete Response (pCR) Using Vacuum-assisted Biopsy (VAB) and Sentinel Lymph Node Biopsy (SLNB) NCT04293796NA1 site๐Ÿ“ Saint Petersburg N.N. Petrov National Medical Research Center of Oncology ยท Tests: Vacuum-assisted biopsy Radiation OmisSion in PAtients With CLinically Node Negative Breast Cancer Undergoing Lumpectomy NCT05866458n/a27 sites๐Ÿ“ Cudgen๐Ÿ“ Liverpool๐Ÿ“ North Sydney Ontario Clinical Oncology Group (OCOG) Biomarker Based Neoadjuvant Strategies for Locally Advanced Resectable ESCC NCT06601309Phase 21 site๐Ÿ“ Fuzhou Fujian Medical University Union Hospital ยท Tests: Serplulimab, Paclitaxel+Cisplatin (Neoadjuvant Chemotherapy), Paclitaxel+Cisplatin(Concurrent Chemoradiotherapy), Radioโ€ฆ Predicting Gastric Cancer Response to Chemo With Multimodal AI Model NCT06451393n/a1 site๐Ÿ“ Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University ยท Tests: Neoadjuvant chemotherapy with radical tumor resection surgery DESCARTES: De-ESCAlation of RadioTherapy in Patients With Pathologic Complete rESponse to Neoadjuvant Systemic Therapy NCT05416164NA1 site๐Ÿ“ Amsterdam The Netherlands Cancer Institute ยท Tests: Omission of radiotherapy The Prognostic Value of the Degree of Pathological Response of Induction Chemotherapy for NPC NCT06182657n/a1 site๐Ÿ“ Nanchang Jiangxi Provincial Cancer Hospital The Efficacy and Safety of De-escalated Postoperative Radiotherapy in Locally Advanced HNSCC With pCR/MPR NCT05854823NA1 site๐Ÿ“ Zhuhai Fifth Affiliated Hospital, Sun Yat-Sen University ยท Tests: dose-reduced radiotherapy ctDNA-Guided Immunotherapy for dMMR/MSI-H Colon Cancer NCT07841236Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: PD-1 inhibitor, CTLA-4 inhibitor, ctDNA/MRD testing, Curative Surgery Romiplostim N01 Plus ATRA for Persistent Isolated Chemotherapy-Induced Thrombocytopenia After Complete Remission of Gynecologic, Breast, or Lung Solid Tumors NCT07586826Phase 21 site๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: Romiplostim N01, All-trans retinoic acid NearWave Optical Molecular Monitoring NCT06744465NA1 site๐Ÿ“ Indianapolis Indiana University ยท Tests: NearWave monitoring Omission of Breast Surgery for Breast Cancer Patients With pCR on MRI and Vacuum-assisted Biopsy After NST (OPTIMIST) NCT05505357NA1 site๐Ÿ“ Seoul Seoul National University Hospital ยท Tests: Breast surgery omission Iparomlimab and Tuvonralimab Plus Paclitaxel and Platinum as Neoadjuvant Therapy for Locally Advanced Cervical Cancer NCT07646301Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Iparomlimab and Tuvonralimab (QL1706), Paclitaxel, Cisplatin, Carboplatin Pyrotinib Plus Trastuzumab and Chemotherapy for HER2-Positive Early Breast Cancer NCT07635342Phase 21 site๐Ÿ“ Shijiazhuang Hebei Medical University Fourth Hospital ยท Tests: Pyrotinib Maleate, Trastuzumab (H, 8mg/kg, pegylated liposomal doxorubicin hydrochloride, Cyclophosphamide, Paclitaxel โ€ฆ THeragnostic Utilities for Neoplastic DisEases of the Rectum by MRI Guided Radiotherapy NCT04815694NA1 site๐Ÿ“ Roma Fondazione Policlinico Universitario Agostino Gemelli IRCCS ยท Tests: RT Dose escalation in LARC patients with an Early Regression Index > 13.1 at second week on nCRT Ph2 Study for Optimization of Adjunct Systemic Therapy in HER2+ Patients, MolecularPCR Trial NCT07407920Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Biospecimen Collection, Hormone Therapy, Pembrolizumab, Pertuzumab, Trastuzumab Perioperative Systemic Therapies in Muscle-Invasive Bladder Cancer (GUARDIANS) NCT07855926n/a1 site๐Ÿ“ Munich LMU Klinikum ยท Tests: Perioperative Systemic Therapy Registry T Cell Lymphoma -Stratified Therapy After Response to First-line Treatment-CR NCT07353840n/a1 site๐Ÿ“ Shanghai Shanghai General Hospital, Shanghai Jiao Tong University Scโ€ฆ ยท Tests: Autologous Hematopoietic Stem Cell Transplantation, Observation Nimotuzumab Combined With Toripalimab and Chemotherapy for Locally Advanced Tonsillar Cancer NCT07353723Phase 21 site๐Ÿ“ Shanxi Tang-Du Hospital ยท Tests: Nimotuzumab, Toripalimab, Nab-paclitaxel, carboplatin
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