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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Previously Treated Non-Small Cell Lung Cancer

Efficacy And Safety Of Anti-PD-1/PD-L1 Antibodies In Combination With Bevacizumab And Metronomic Cyclophosphamide In Patients With Non-Small Cell Lung Cancer And Cutaneous Melanoma Previously Treated With Immune Checkpoint Blockade NCT07130032Phase 21 site📍 Saint Petersburg EuroCityClinic LLC · Tests: reICB regimen (NSCLC), reICB regimen (melanoma) Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer NCT03851445Phase 2, Phase 31229 sites📍 Birmingham📍 Daphne📍 Fairhope SWOG Cancer Research Network · Tests: Screening Platform A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non-Small Cell Lung Cancer NCT07659782Phase 224 sites📍 Scottsdale📍 Los Angeles📍 Los Angeles Verastem, Inc. · Tests: VS-7375 A Study Evaluating The Combination of Immunotherapy With Radiotherapy in Non-Small Cell Lung Cancer NCT07603856Phase 21 site📍 Chicago University of Chicago · Tests: Investigator Choice Immunotherapy (for example: pembrolizumab, cemiplimab, durvalumab, ipilimumab plus nivolumab), Inve… Treatment for Advanced Non-small Cell Lung Cancer With Actionable Genomic Alterations After Targeted Treatment and Chemotherapy (An Expanded Lung-MAP Treatment Trial) NCT07393555Phase 241 sites📍 Berkeley📍 Palo Alto📍 Sacramento SWOG Cancer Research Network · Tests: Biospecimen Collection, Computed Tomography, Ivonescimab, Magnetic Resonance Imaging, Sacituzumab Govitecan A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors NCT06983743Phase 19 sites📍 Santa Rosa📍 Aurora📍 Sarasota Erasca, Inc. · Tests: ERAS-0015, ERAS-0015 in combination A Study of Vebreltinib and Platinum-Containing Double Agents in Subjects With MET-Positive NCT06930794Phase 32 sites📍 Beijing📍 Guangzhou Beijing Pearl Biotechnology Limited Liability Company · Tests: Vebreltinib combined with platinum-based doublet chemotherapy., platinum-based doublet chemotherapy. A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors NCT07020117Phase 114 sites📍 Duarte📍 Irvine📍 Miami Aktis Oncology, Inc. · Tests: [225Ac]Ac-AKY-1189 (therapeutic), [64Cu]Cu-AKY-1189 (imaging) A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC) NCT06568939Phase 283 sites📍 Chandler📍 Little Rock📍 Los Angeles AbbVie · Tests: Telisotuzumab Vedotin A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F) NCT07286149Phase 1, Phase 229 sites📍 Clermont📍 Chicago📍 Portland Merck Sharp & Dohme LLC · Tests: MK-1084, Patritumab deruxtecan, Sacituzumab tirumotecan, Cetuximab, Rescue Medications Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations NCT07291037Phase 3206 sites📍 Chandler📍 Gilbert📍 Goodyear AstraZeneca · Tests: Datopotamab deruxtecan (Dato-DXd), Docetaxel Tepotinib vs Standard Treatment in Patients With Advanced MET Exon 14 Mutated Non-Small Cell Lung Cancer Previously Treated NCT06908993Phase 329 sites📍 Besançon📍 Bordeaux📍 Brest Intergroupe Francophone de Cancerologie Thoracique · Tests: Tepotinib, Pemetrexed (Alimta), Vinorelbine, Gemcitabine alone, Docetaxel A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors NCT06695845Phase 228 sites📍 Prescott📍 Littleton📍 Fort Myers Jazz Pharmaceuticals · Tests: Zanidatamab A Global Phase II/III Clinical Study to Evaluate the Efficacy and Safety of HLX43 Monotherapy or HLX43 in Combination With HLX07 Versus Docetaxel in Advanced or Metastatic Squamous Non-Small Cell Lung Cancer NCT07459751Phase 2, Phase 31 site📍 Beijing Shanghai Henlius Biotech · Tests: HLX43, HLX43+HLX07, Docetaxel A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC) NCT04928846Phase 3317 sites📍 Birmingham📍 Chandler📍 Phoenix AbbVie · Tests: Telisotuzumab Vedotin, Docetaxel The Efficacy and Safety of LMV-12 Combined With Osimertinib in NSCLC NCT06109558Phase 1, Phase 21 site📍 Changsha Hunan Province Tumor Hospital · Tests: LMV-12(HE003) Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301) NCT06881784Phase 3158 sites📍 Birmingham📍 Long Beach📍 New Haven Revolution Medicines, Inc. · Tests: daraxonrasib, docetaxel Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial) NCT06616584Phase 2, Phase 3413 sites📍 Daphne📍 Fairhope📍 Mobile SWOG Cancer Research Network · Tests: Biospecimen Collection, Cemiplimab, Computed Tomography, Dexamethasone, Docetaxel EMPATHY NSCLC: European Registry for Plasma-Based Molecular Profiling in Advanced NSCLC Patients NCT07096258n/a4 sites📍 Nancy📍 Naples📍 Madrid Hedera Dx SA A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01) NCT06780085Phase 236 sites📍 Lexington📍 Baltimore📍 Pittsburgh Merck Sharp & Dohme LLC · Tests: Raludotatug Deruxtecan, Ifinatamab Deruxtecan, Docetetaxel, 5-hydroxytryptamine subtype 3 receptor antagonist, Neurokin… A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC) NCT07144280Phase 3447 sites📍 Alabaster📍 Bessemer📍 Birmingham Pfizer · Tests: PF-08046054, Docetaxel monotherapy Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01I/KEYMAKER-U01I) NCT06780098Phase 246 sites📍 Lexington📍 Baltimore📍 Dallas Merck Sharp & Dohme LLC · Tests: R-DXD, I-DXD, Docetaxel, Rescue Medications, Rescue Medication Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations NCT06772623Phase 1, Phase 2127 sites📍 Phoenix📍 Fullerton📍 Oxnard AbbVie · Tests: Telisotuzumab Adizutecan, Budigalimab, Pembrolizumab, Pembrolizumab, Carboplatin A Phase II Study of HS-20093 Injection Combined With Adebrelimab Versus HS-20093 Injection in Previously Treated Patients With Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer Without Actionable Genomic Alterations NCT07824882Phase 21 site📍 Wuhan Hansoh BioMedical R&D Company · Tests: HS-20093 for Injection, Adebrelimab Injection A Clinical Study of JMT101 in Combination With Osimertinib Versus Osimertinib Alone as First-Line Treatment for Patients With Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Harboring Epidermal Growth Factor Receptor (EGFR) Sensitive Mutations NCT06735391Phase 31 site📍 Guangzhou Shanghai JMT-Bio Inc. · Tests: JMT101, Osimertinib A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC) NCT07140016Phase 117 sites📍 Fullerton📍 Orange📍 Edwards Astellas Pharma Global Development, Inc. · Tests: gilteritinib A Study of the Safety and Efficacy of Pemetrexed Combined with Nivolumab Via Intraventricular Injection for the Treatment of Refractory Non-squamous Non-small Cell Lung Cancer with Leptomeningeal Metastases NCT06901817Phase 21 site📍 Shanghai Shanghai Cancer Hospital, China · Tests: Intraventricular Pemetrexed, Intraventricular Nivolumab, Intraventricular Dexamethasone A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202) NCT07361510Phase 3283 sites📍 Daphne📍 Bullhead City📍 Glendale Bristol-Myers Squibb · Tests: Pumitamig, Pembrolizumab Study of Treatment With Sacituzumab and Zimberelimab for Patients With Lung Cancer Confined to the Chest and Previously Operated on Who Were Not Disease-free. NCT06431633Phase 332 sites📍 Alicante📍 Elche📍 Badalona Fundación GECP · Tests: Zimberelimab, Sacituzumab govitecan, Cisplatin, Carboplatin Sotorasib in Previously Treated Locally Advanced or Metastatic NSCLC Subjects With Mutated KRAS p.G12C NCT05631249Phase 25 sites📍 Lyon📍 Marseille📍 Paris Gustave Roussy, Cancer Campus, Grand Paris · Tests: Sotorasib 120Mg Tab
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