🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

🧪

Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

30 recruiting trials

for Rectal Cancer Stage III

DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer NCT06275958Phase 336 sites📍 's-Hertogenbosch📍 Alkmaar📍 Amstelveen Leiden University Medical Center · Tests: Doublet Chemotherapy, Standard Dose (100%), Doublet Chemotherapy, Dose-reduced (75%), Monotherapy, Standard Dose (100%)… Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer NCT06307548Phase 1, Phase 21 site📍 Buffalo Roswell Park Cancer Institute · Tests: Aminolevulinic Acid, Biospecimen Collection, Computed Tomography, Fluorescence-Guided Surgery, Magnetic Resonance Imagi… Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery NCT03051464Phase 2, Phase 34 sites📍 Dallas📍 Montreal📍 Montreal Sir Mortimer B. Davis - Jewish General Hospital · Tests: Complete responders and Non-complete responders, Chemoradiation + EBRT Boost, Chemoradiation + HDRBT Boost Sacituzumab Govitecan in Metastatic Colorectal Cancer NCT06243393Phase 2, Phase 31 site📍 Heidelberg University Hospital Heidelberg · Tests: Sacituzumab Govitecan (SG), Physicians Choice (PhC). CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors NCT05733000Phase 21 site📍 Chicago Northwestern University · Tests: Biospecimen Collection, Computed Tomography, Devimistat, Fluorouracil, Gemcitabine Hydrochloride ctDNA Monitoring to Predict the Efficacy of TNT for Rectal Cancer NCT06589388n/a1 site📍 Ho Chi Minh City Gene Solutions Exploring the Treatment Duration of PD-1 Neoadjuvant Therapy in Stage II-III dMMR Rectal Cancer NCT06613165n/a1 site📍 Xi'an Xijing Hospital Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic Cancer, ID-COMET Trial NCT06563388Phase 31 site📍 Buffalo Roswell Park Cancer Institute · Tests: Stereotactic Ablative Radiotherapy, Best Practice Surgery Plus Chemo Versus Chemoradiotherapy Followed by Surgery Plus Chemo for Locally Recurrent Rectal Cancer NCT04288999Phase 345 sites📍 Chiba📍 Gifu📍 Hidaka National Cancer Center Hospital East · Tests: Chemotherapy, Preoperative radiotherapy, Procedure Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors NCT04771520Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Avapritinib Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors NCT04165772Phase 210 sites📍 Hartford📍 Miami📍 Basking Ridge Memorial Sloan Kettering Cancer Center · Tests: TSR-042 or Dostarlimab, capecitabine or 5-FU, Intensity Modulated Radiation Therapy (IMRT) Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection NCT05939687Phase 31 site📍 Moscow Blokhin's Russian Cancer Research Center · Tests: mesh, non-mesh The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial NCT06565052NA2 sites📍 Boston📍 Boston Dana-Farber Cancer Institute · Tests: Prehabilitation Program Rectal Cancer CTC Trial NCT07194616NA4 sites📍 Olomouc📍 Olomouc📍 Ostrava University Hospital Ostrava · Tests: Primary Surgery, Neoadjuvant radiochemotherapy and surgery mFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC NCT06791512Phase 31 site📍 Guangzhou Jun Huang · Tests: mFOLFOX6 + Bevacizumab + PD-1 monoclonal antibody, mFOLFOX6 Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer NCT04511039Phase 11 site📍 Buffalo Roswell Park Cancer Institute · Tests: Trifluridine and Tipiracil Hydrochloride, Talazoparib Tosylate Efficacy of Hyperthermic Intraperitoneal Chemotherapy NCT04861558Phase 35 sites📍 Ahmedabad📍 Gothenburg📍 Malmö Uppsala University · Tests: 5Fluorouracil, Irinotecan, Oxaliplatin Post-resection/Ablation Chemotherapy in Patients With Metastatic Colorectal Cancer (FIRE-9 - PORT / AIO-KRK-0418) NCT05008809Phase 379 sites📍 Amberg📍 Bad Saarow📍 Bayreuth Dominik Paul Modest · Tests: mFOLFOX6, mFOLFOXIRI, FOLFIRI, CAPOX Hyperthermia With Chemoradiotherapy in Rectal Cancer NCT06831981NA2 sites📍 Tübingen📍 Tübingen University Hospital Tuebingen · Tests: Hyperthermia, Radiotherapy, Chemotherapy with 5-fluorouracil, Consolidation chemotherapy with FOLFOX Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study NCT04739072n/a10 sites📍 Gilbert📍 Jacksonville📍 Honolulu M.D. Anderson Cancer Center · Tests: Biospecimen Collection, Electronic Health Record Review Neoadjuvant Radiotherapy for Rectal Adenocarcinoma With Capecitabine Versus TAS-102 (Neo-REACT): A Multi-center, Randomized, Phase III Trial NCT06850090Phase 31 site📍 Jinan Shandong Cancer Hospital and Institute · Tests: TAS-102, Capecitabine UGT1A1-Based Irinotecan Therapy for Locally Advanced Rectal Cancer NCT05148767Phase 41 site📍 Hangzhou Zhejiang Cancer Hospital · Tests: Neoadjuvant chemoradiotherapy based on irinotecan Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer NCT07147231Phase 1, Phase 27 sites📍 Aurora📍 Washington D.C.📍 Atlanta National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cemiplimab, Computed Tomography, Magnetic Resonance Imaging A Clinical Study of Adebrelimab in Combination With SHR-8068 and Chemoradiotherapy as Perioperative Therapy for Locally Advanced Rectal Cancer NCT07454720Phase 2, Phase 32 sites📍 Wuhan📍 Hangzhou Suzhou Suncadia Biopharmaceuticals Co., Ltd. · Tests: Adebrelimab in combination with SHR-8068 and chemotherapy, Adebrelimab combined with chemotherapy, Chemotherapy Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer NCT06696768Phase 113 sites📍 Gainesville📍 Shiloh📍 Fairway National Cancer Institute (NCI) · Tests: Bevacizumab, Biopsy Procedure, Biospecimen Collection, Computed Tomography, Emavusertib PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal Cancer NCT05236972Phase 31 site📍 Guangzhou Sun Yat-sen University · Tests: Sintilimab, Oxaliplatin, capecitabine Postoperative Circulating Tumor DNA Monitoring in Stage I-III Driver-Mutant Colon Adenocarcinoma NCT07795528n/a1 site📍 Shanghai Ruijin Hospital · Tests: Longitudinal ctDNA-MRD NGS testing at scheduled postoperative time points Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients" NCT01365169NA1 site📍 Houston M.D. Anderson Cancer Center · Tests: Exercise Intervention, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA NCT05797077Phase 31 site📍 Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University · Tests: Colorectal resection surgery., FOLFOX chemotherapy regimen, Capecitabine Thymosin-alpha 1 for Adjuvant Treatment After Radical Resection of High-risk Stage II and III Colorectal Cancer NCT05086614Phase 31 site📍 Shanghai Fudan University · Tests: Thymosin Alpha1
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy