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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

30 recruiting trials

for Rectum Cancer, Adenocarcinoma

Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma NCT05752136Phase 31 site📍 Hangzhou Sir Run Run Shaw Hospital · Tests: Envafolimab Neoadjuvant Chemoradiotherapy Plus Tislelizumab With or Without Probio-M9 in pMMR/MSS Locally Advanced Rectal Cancer NCT07458529Phase 21 site📍 Beijing Seventh Medical Center of PLA General Hospital · Tests: CRT+PD-1 inhibitor+Probio-M9, CRT+PD-1 inhibitor+placebo A Study of Response to Standard Treatment Before Surgery in People With Rectal Cancer NCT06637462NA6 sites📍 Middletown📍 Montvale📍 Commack Memorial Sloan Kettering Cancer Center · Tests: Endoscopy Prospective Monocentric Study Evaluating the Circulating NK Cells Phenotype and the ImmunoScore® in Patients With Non Metastatic Rectal Cancer NCT06536127NA1 site📍 Avignon Institut Sainte Catherine · Tests: Blood samples Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors NCT04165772Phase 210 sites📍 Hartford📍 Miami📍 Basking Ridge Memorial Sloan Kettering Cancer Center · Tests: TSR-042 or Dostarlimab, capecitabine or 5-FU, Intensity Modulated Radiation Therapy (IMRT) Nordic ORgan Preservation Pilot Approach Nonrandomised Single-Arm Trial for Non-Operative Management of Rectal Cancer NCT06328361NA13 sites📍 Tallinn📍 Tallinn📍 Tallinn Tampere University Hospital · Tests: Nonoperative surveillance Intestinal Microbiome Modulation With Antibiotics in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer NCT06793137Phase 21 site📍 São Paulo AC Camargo Cancer Center · Tests: Metronidazole mFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC NCT06791512Phase 31 site📍 Guangzhou Jun Huang · Tests: mFOLFOX6 + Bevacizumab + PD-1 monoclonal antibody, mFOLFOX6 Clonal Hematopoiesis Chemotherapy and Radiation Effects Study NCT07675967n/a1 site📍 Boston Dana-Farber Cancer Institute · Tests: Samples Interest of PET-MRI in the Evaluation of the Response After Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma NCT05772481n/a1 site📍 Strasbourg Centre Paul Strauss · Tests: PET-MRI Evaluation Contact X-ray Brachytherapy for Rectal Preservation in Intermediate Substage Rectal Adenocarcinoma NCT06402864Phase 311 sites📍 Avignon📍 Lyon📍 Lyon Gustave Roussy, Cancer Campus, Grand Paris · Tests: contact X-ray brachytherapy (CXB) SCRT Followed by CAPOX + Bev ± PD-1 Inhibitor for TNT in LARC NCT07198165Phase 21 site📍 Shanghai Ruijin Hospital · Tests: PD-1 inhibitor based immunotherapy Neoadjuvant Radiotherapy for Rectal Adenocarcinoma With Capecitabine Versus TAS-102 (Neo-REACT): A Multi-center, Randomized, Phase III Trial NCT06850090Phase 31 site📍 Jinan Shandong Cancer Hospital and Institute · Tests: TAS-102, Capecitabine Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors NCT06239194Phase 1, Phase 26 sites📍 Denver📍 Miami📍 Boston ModeX Therapeutics, An OPKO Health Company · Tests: MDX2001 A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies NCT05669430Phase 1, Phase 213 sites📍 Los Angeles📍 Denver📍 New Haven GV20 Therapeutics · Tests: GV20-0251, GV20-0251, GV20-0251 and Pembrolizumab [KEYTRUDA®], GV20-0251 and Pembrolizumab [KEYTRUDA®] Upfront Trastuzumab-Deruxtecan Plus Capecitabine and Bevacizumab for Patients With HER-2 Positive Metastatic Colorectal Cancer. NCT07407465Phase 228 sites📍 Lyon📍 Marseille📍 Paris Gruppo Oncologico del Nord-Ovest · Tests: Trastuzumab-Deruxtecan (T-DXd), Capecitabine, Bevacizumab FAPI-Guided Radiotherapy With Cadonilimab and Standard Chemotherapy for Colorectal Peritoneal Metastasis: A Phase III Randomized Controlled Trial (TORHC-PM02) NCT07815834Phase 31 site📍 Shanghai Fudan University · Tests: Second-Line Chemotherapy, Radiation Therapy, Cadonilimab (AK104) A Study to Evaluate the Efficacy of VVD-133214 in Combination With Pembrolizumab Compared With Pembrolizumab Alone in Participants With Advanced Cancer of the Colon or Rectum NCT07811193Phase 2122 sites📍 Tucson📍 Ann Arbor📍 Detroit Vividion Therapeutics, Inc. · Tests: VVD-133214, Pembrolizumab Family Communications After Genetic Testing NCT07143487NA360 sites📍 Anchorage📍 Anchorage📍 Anchorage Alliance for Clinical Trials in Oncology · Tests: Biospecimen Collection, Genetic Testing, Communication Intervention, Survey Administration Preoperative Short-Course Radiation Therapy With PROtons Compared to Photons In High-Risk RECTal Cancer (PRORECT) NCT04525989NA9 sites📍 Stockholm📍 Gävle📍 Gothenburg Alexander Valdman · Tests: Radiation therapy Beyond TME Origins NCT02292641NA4 sites📍 Oslo📍 Harrow📍 Oxford Imperial College London · Tests: New Radiological Staging Classification system for patients with advanced and recurrent colorectal cancer undergoing pe… A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations NCT07629960Phase 1, Phase 216 sites📍 Sarasota📍 Tampa📍 Baton Rouge Blueprint Medicines Corporation · Tests: BLU-924 A Multicenter, Randomized Controlled Phase II Study of Short-Course Radiotherapy Followed by Sequential PD-1 Inhibitor and FOLFOX Chemotherapy Versus Long-Course Chemoradiotherapy for High-Risk Locally Advanced pMMR/MSS Lower Rectal Adenocarcinoma (STAR Trial) NCT07669220Phase 21 site📍 Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University · Tests: Short-course Radiotherapy, SCRT, Toripalimab ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation NCT05059444n/a57 sites📍 Birmingham📍 Chandler📍 Hot Springs Guardant Health, Inc. · Tests: Guardant Reveal FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery NCT06780787Phase 21 site📍 Duarte City of Hope Medical Center · Tests: Balstilimab, Biospecimen Collection, Botensilimab, Capecitabine, Computed Tomography SCRT + Chemo Targeted Immuno-neoadjuvant Therapy for High-risk pMMR/MSS RC NCT07549399Phase 31 site📍 Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University · Tests: Short-Course Radiotherapy, PD-1 monoclonal antibody, mFOLFOX6 regimen, Cetuximab, Bevacizumab Trans-Artery/Intra-Tumor Infusion of Checkpoint Inhibitors Plus Chemodrug for Immunotherapy of Advanced Solid Tumors NCT03755739Phase 2, Phase 31 site📍 Guanzhou Second Affiliated Hospital of Guangzhou Medical University · Tests: Checkpoint inhibitor (CPI) such as Pembrolizumab plus chemotherapy Simultaneous Boost in Neoadjuvant Radiotherapy for Rectal Cancer NCT07200141Phase 21 site📍 Beijing Peking Union Medical College Hospital · Tests: GTV 58.75 Gy/25 fractions(Simultaneous Integrated Boost), GTV 50 Gy/25 fractions(Simultaneous Integrated Boost), Concur… Personalized DC Vaccine for Postoperative Cancer NCT04147078Phase 11 site📍 Chengdu Sichuan University · Tests: DC vaccine subcutaneous administration Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation NCT04668872n/a1 site📍 New York Memorial Sloan Kettering Cancer Center · Tests: Y90 TARE, PET/CT, PET/MRI
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