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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Recurrent Glioma

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). NCT06607692Phase 1, Phase 21 site📍 Boadilla del Monte Fundación de investigación HM · Tests: Olaparib; 177Lu-DOTATATE Sonodynamic Therapy in Patients With Recurrent GBM NCT06039709Phase 11 site📍 Charlottesville Shayan Moosa, MD · Tests: 5-ALA and Low-Intensity Focused Ultrasound (SDT) Predictive Value of Soluble CD146 in Glioblastoma Patients NCT06001281NA1 site📍 Marseille Assistance Publique Hopitaux De Marseille · Tests: plasma collection Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas NCT07544992Phase 11 site📍 Duarte City of Hope Medical Center · Tests: Autologous Anti-EGFR/Anti-IL13Ralpha2 CAR T-cells, Biopsy Procedure, Biospecimen Collection, Echocardiography Test, FDG… Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma NCT06815029Phase 11 site📍 Duarte City of Hope Medical Center · Tests: Biospecimen Collection, Chimeric Antigen Receptor T-Cell Therapy, Echocardiography, Fludeoxyglucose F-18, Intracranial … Evaluating Safety, Tolerability, and Preliminary Efficacy of YSCH-01 Monotherapy and in Combination With Atezolizumab for Recurrent Glioblastoma NCT07538128EARLY Phase 11 site📍 Shanghai Huashan Hospital · Tests: YSCH-01, Atezolizumab (1200 mg every three weeks) Evaluation of Clinical Efficacy and Safety of Specific Mode Electroacupuncture Stimulation for Paclitaxel Across BBB Delivery in Patients With Postoperative Recurrence of Malignant Glioma: A Single-arm Trial NCT06818331Phase 21 site📍 China The Third Affiliated hospital of Zhejiang Chinese Medical U… · Tests: SMES+PTX, Paclitaxel, Specific mode electroacupuncture stimulation BRiTE - Bispecific T Cell Engager for Patients With Glioblastoma NCT04903795Phase 11 site📍 Durham Mustafa Khasraw, MBChB, MD, FRCP, FRACP · Tests: hEGFRvIII-CD3 (BRiTE) Study of How Safe and Effective Tarlatamab is in Brain Cancers NCT06776250Phase 21 site📍 Toronto University Health Network, Toronto · Tests: Tarlatamab A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM NCT05303467Phase 19 sites📍 Birmingham📍 San Diego📍 San Francisco Boston Scientific Corporation · Tests: TheraSphere GBM Multiple Intracerebral Doses of Neural Stem Cell-Based Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas NCT05139056Phase 14 sites📍 Duarte📍 Stanford📍 Chicago City of Hope Medical Center · Tests: Neural Stem Cells-expressing CRAd-S-pk7, Resection Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature NCT06894225Phase 21 site📍 Singapore National Neuroscience Institute · Tests: ACT001 Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual Disease NCT07346157Phase 1, Phase 23 sites📍 San Francisco📍 Washington D.C.📍 Seattle Sabine Mueller, MD, PhD · Tests: Liothyronine (L-T3), Bevacizumab, Irinotecan, Temozolomide (TMZ) Advanced Diffusion MRI to Differentiate Tumor Recurrence From Pseudoprogression in Patients With Glioblastoma and Brain Metastases NCT05911230NA1 site📍 Basel University Hospital, Basel, Switzerland · Tests: Advanced diffusion-weighted MRI (ADW-MRI) Relapsed and Progressive Sonic Hedgehog Medulloblastoma With U1 Mutation Registry Study NCT07242963n/a2 sites📍 Houston📍 Houston Mohammad H. Abu Arja A Phase 0/1 Clinical Trial With an Expansion Phase of GSK5764227, a B7-H3-Targeted Antibody-Drug Conjugate (ADC), in Patients With Recurrent Grade 4 Glioma and Patients With Brain Metastases NCT07268053EARLY Phase 11 site📍 Phoenix Nader Sanai · Tests: Risvutatug rezetecan Use of Pulsed Low-dose Rate Re-irradiation for Recurrent Glioma (PULSAR) NCT06055517NA1 site📍 Aviano Centro di Riferimento Oncologico - Aviano · Tests: Pulsed low dose-rate radiotherapy (pLDRT) Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma NCT04540107Phase 11 site📍 San Francisco Susan Chang · Tests: Hyperpolarized Carbon C 13 Pyruvate, Magnetic Resonance Imaging, Magnetic Resonance Spectroscopic Imaging Combination Therapy for the Treatment of Diffuse Midline Gliomas NCT05009992Phase 232 sites📍 Birmingham📍 Los Angeles📍 San Diego University of California, San Francisco · Tests: ONC201, Radiation Therapy, Paxalisib, DNX-2401 Intraarterial Carboplatin + Caelyx vs Intraarterial Carboplatin + Etoposide Phosphate for Progressing Glioblastoma NCT06356883Phase 21 site📍 Sherbrooke Université de Sherbrooke · Tests: IA Carboplatin + IA Caelyx, IA Carboplatin + IA Etoposide Phosphate GPC-3 CAR T CELLS FOR Recurrent GPC-3 Positive Glioblastoma NCT06815432Phase 11 site📍 Houston Baylor College of Medicine · Tests: 15.GPC3-CAR T cells Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors NCT05283330Phase 18 sites📍 Chicago📍 Iowa City📍 Lexington Orano Med Theranostics, SAS · Tests: ²¹²Pb-DOTAM-GRPR1 ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors NCT04732065Phase 17 sites📍 San Francisco📍 Washington D.C.📍 Atlanta Sabine Mueller, MD, PhD · Tests: ONC206, Standard of Care Radiation Therapy, Optional Proton (1H) MR spectroscopy (MRS) A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma NCT07579208Phase 11 site📍 Houston M.D. Anderson Cancer Center · Tests: NK Cells, NK Cells Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors NCT07584499Phase 11 site📍 Guangzhou Sun Yat-sen University · Tests: Becotatug Vedotin NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors NCT07664176Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: NeuroNavigation-Guided Focused Ultrasound (NgFUS), Lumason, Nivolumab A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma, GHoST Trial NCT07074756NA2 sites📍 Jacksonville📍 Rochester Mayo Clinic · Tests: Chemotherapy, Computed Tomography, Internet-Based Intervention, Magnetic Resonance Imaging, Neurologic Examination Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188Phase 1, Phase 21 site📍 Bethesda National Institute of Neurological Disorders and Stroke (NI… · Tests: LMP744, Conventional Surgery or Biopsy All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma NCT05345002Phase 21 site📍 Philadelphia Stephen Bagley, MD, MSCE · Tests: Retifanlimab, All-trans retinoic acid MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas NCT06712875Phase 1, Phase 23 sites📍 Washington D.C.📍 Chicago📍 New York Ann & Robert H Lurie Children's Hospital of Chicago · Tests: Trametinib and Nivolumab, Dabrafenib, trametinib, nivolumab
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