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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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22 recruiting trials

for Recurrent Medulloblastoma

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). NCT06607692Phase 1, Phase 21 site📍 Boadilla del Monte Fundación de investigación HM · Tests: Olaparib; 177Lu-DOTATATE Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual Disease NCT07346157Phase 1, Phase 23 sites📍 San Francisco📍 Washington D.C.📍 Seattle Sabine Mueller, MD, PhD · Tests: Liothyronine (L-T3), Bevacizumab, Irinotecan, Temozolomide (TMZ) Relapsed and Progressive Sonic Hedgehog Medulloblastoma With U1 Mutation Registry Study NCT07242963n/a2 sites📍 Houston📍 Houston Mohammad H. Abu Arja Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors NCT07584499Phase 11 site📍 Guangzhou Sun Yat-sen University · Tests: Becotatug Vedotin NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors NCT07664176Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: NeuroNavigation-Guided Focused Ultrasound (NgFUS), Lumason, Nivolumab Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors NCT04185038Phase 11 site📍 Seattle Seattle Children's Hospital · Tests: SCRI-CARB7H3(s); B7H3-specific chimeric antigen receptor (CAR) T cel A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites📍 Washington D.C.📍 Gainesville University of Florida · Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP li… A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies. NCT07017816EARLY Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: SGT-53, hypofractionated radiotherapy with immunotherapy, Nivolumab DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma NCT04696029Phase 226 sites📍 Little Rock📍 Oakland📍 Sacramento Giselle Sholler · Tests: Difluoromethylornithine HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors NCT03911388Phase 13 sites📍 Birmingham📍 St Louis📍 Houston M.D. Anderson Cancer Center · Tests: G207 A Study of 177Lu-DTPA-Omburtamab in Children and Adolescents With Brain Cancer or Cancer That Has Spread to the Central Nervous System (CNS) NCT07698899Phase 17 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: 25 mCi 177Lu- DTPA-omburtamab Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT) NCT06193759Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: Multi-tumor antigen specific cytotoxic T lymphocytes (TSA-T) directed against proteogenomically determined personalized… Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma, ATRT and Rare CNS Tumors NCT01356290Phase 222 sites📍 Chicago📍 Boston📍 Grand Rapids Medical University of Vienna · Tests: Bevacizumab, Thalidomide, Celecoxib, Fenofibric acid, Etoposide B7-H3.CD28Z.CART in CNS Neoplasms NCT07390539Phase 12 sites📍 Boston📍 Boston Robbie Majzner · Tests: B7-H3.CD28Z.CART, Fludarabine, Cyclophosphamide Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With Medulloblastoma NCT06514898Phase 12 sites📍 Washington D.C.📍 Gainesville University of Florida · Tests: TTRNA-DC vaccines with GM-CSF, TTRNA-xALT, Td vaccine, autologous HSCs, Pembrolizumab Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma NCT05057702NA9 sites📍 Los Angeles📍 San Diego📍 San Francisco University of California, San Francisco · Tests: Specialized Tumor Board Treatment Plan, Combinations Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms NCT04541082Phase 11 site📍 Bethesda Jazz Pharmaceuticals · Tests: ONC206 Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors NCT05278208Phase 1, Phase 24 sites📍 Aurora📍 Cincinnati📍 Columbus Nationwide Children's Hospital · Tests: LUTATHERA® (Lutetium Lu 177 dotatate) PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma NCT05096481Phase 213 sites📍 Aurora📍 Washington D.C.📍 Miami Nationwide Children's Hospital · Tests: PEP-CMV, Temozolomide, Tetanus Diphtheria Vaccine PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications NCT06161519Phase 1, Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: PLX038 GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults NCT07087002Phase 11 site📍 Palo Alto Stanford University · Tests: GPC2-CAR T cells, Fludarabine, Cyclophosphamide Apatinib Combined with Temozolomide and Etoposide Capsules in the Treatment of Recurrent Medulloblastoma in Children NCT04501718Phase 21 site📍 Beijing Beijing Sanbo Brain Hospital · Tests: Apatinib Combined With Temozolomide and Etoposide Capsules
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