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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Severe Aplastic Anemia

Investigation of the Genetics of Hematologic Diseases NCT02720679n/a1 site📍 Memphis St. Jude Children's Research Hospital CD7 CAR-T Bridging to alloHSCT for Severe Aplastic Anemia NCT06633328EARLY Phase 11 site📍 Hanzhou Zhejiang University · Tests: CD7 CAR-T cells injection, Allogeneic hematopoietic stem cell transplantation TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Non-Malignant Hematological Disorders in Children NCT04356469Phase 21 site📍 St. Petersburg Johns Hopkins All Children's Hospital · Tests: Haploidentical Hematopoietic Cell Transplantation Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC NCT04528355n/a1 site📍 Pittsburgh Paul Szabolcs · Tests: data collection Natural History of Acquired and Inherited Bone Marrow Failure Syndromes NCT05012111n/a1 site📍 Bethesda National Heart, Lung, and Blood Institute (NHLBI) A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) NCT01351545n/a142 sites📍 Birmingham📍 Gilbert📍 Phoenix Center for International Blood and Marrow Transplant Resear… · Tests: A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias NCT03653338Phase 1, Phase 21 site📍 Pittsburgh Paul Szabolcs · Tests: CD3/CD19 depleted leukocytes, CD45RA depleted leukocytes, Hydroxyurea, Rituximab, Alemtuzumab Reduced Dose of Cyclophosphamide Combined With Standard Immunosuppressive Therapy to Treat Severe Aplastic Anemia NCT06695741Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Reduced dose of cyclophosphamide combined with standard immunosuppressive therapy Phase I/II Study of Anti-CD38 Monoclonal Antibody in Refractory Severe Aplastic Anemia NCT07714512Phase 1, Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Isatuximab Clinical Study on Modified Allogeneic Hematopoietic Stem Cell Transplantation Regimen for Severe Aplastic Anemia NCT06378060Phase 21 site📍 Kunming Hematology department of the 920th hospital · Tests: Modified transplantation system A Novel Conditioning Regimen for Haplo-HSCT in Older Patients With SAA NCT07586735n/a1 site📍 Beijing Peking University People's Hospital · Tests: BFCA conditiong regimen Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia NCT06517641Phase 225 sites📍 Birmingham📍 Duarte📍 Los Angeles Medical College of Wisconsin · Tests: Haploidentical donor bone marrow transplant, Unrelated donor bone marrow transplant HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy NCT02143830Phase 23 sites📍 New York📍 Cincinnati📍 Seattle Children's Hospital Medical Center, Cincinnati · Tests: Busulfan, Cyclophosphamide, Fludarabine, rabbit ATG, G-CSF MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure. NCT06412497Phase 21 site📍 Minneapolis Masonic Cancer Center, University of Minnesota · Tests: Rituximab, Rabbit ATG, Cyclophosphamide, Fludarabine, Total Body Irradiation Enhancing the Clinical Management of CMF Through a National Pediatric and Adult Network Based on Biological and Genetic Data NCT07877727n/a4 sites📍 Avellino📍 Genova📍 Naples Istituto Giannina Gaslini A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic Anemia NCT05757310Phase 11 site📍 Duarte City of Hope Medical Center · Tests: Anti-Thymocyte Globulin, Biospecimen Collection, Bone Marrow Aspirate, Bone Marrow Biopsy, Cyclophosphamide Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis NCT03520647Phase 21 site📍 Bethesda National Heart, Lung, and Blood Institute (NHLBI) · Tests: Cyclophosphamide, Peripheral Blood Stem Cells Peripheral Blood Versus Bone Marrow Plus Peripheral Blood Grafts for Haploidentical Transplantation in Severe Aplastic Anemia NCT07629947NA1 site📍 Beijing Peking University People's Hospital · Tests: G-CSF-Primed Peripheral Blood Stem Cell Graft, G-CSF-Primed Bone Marrow Plus Peripheral Blood Stem Cell Graft Rituximab for Serious Aplastic Anemia With Platelet Transfusion Refractoriness NCT06254560Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Rituximab Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders NCT03579875Phase 21 site📍 Minneapolis Masonic Cancer Center, University of Minnesota · Tests: Total Body Irradiation (TBI) (Plan 1), Cyclophosphamide (CY) (Plan 1), Fludarabine (FLU), Methylprednisolone (MP), Dono… Early Initiation of Oral Therapy With Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA) NCT04304820Phase 21 site📍 Bethesda National Heart, Lung, and Blood Institute (NHLBI) · Tests: Eltrombopag, Cyclosporine, Horse-Anti-thymocyte-Globulin Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor NCT03214354Phase 21 site📍 Calgary University of Calgary · Tests: Alemtuzumab, Total Body Irradiation, Sirolimus HPC Offered for PRESERVE Expansion NCT07145411n/a4 sites📍 Birmingham📍 Detroit📍 Columbus Ossium Health, Inc. · Tests: Bone Marrow Transplant with Ossium's HPC, Marrow (bone marrow recovered from deceased organ and tissue donors) Dose-attenuated IST and Hetrombopag in Elderly (≥65 Years) Patients With Severe Aplastic Anemia NCT07010237Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Dose-attenuated IST and Hetrombopag CD7 CAR T Cells (RD13-02) in the Treatment of Relapsed/Refractory Severe Aplastic Anemia NCT06622694Phase 11 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: RD13-02 Haploidentical HCT for Severe Aplastic Anemia NCT04558736Phase 21 site📍 Memphis St. Jude Children's Research Hospital · Tests: Anti-Thymocyte Globulin (Rabbit), Fludarabine, Cyclophosphamide, Mesna, G-CSF Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT NCT01962415Phase 21 site📍 Pittsburgh Paul Szabolcs · Tests: Hydroxyurea, Alemtuzumab, Fludarabine, Melphalan, Thiotepa Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer NCT01137643n/a1 site📍 Chapel Hill UNC Lineberger Comprehensive Cancer Center · Tests: biologic sample preservation procedure, cytology specimen collection procedure Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells NCT01174108Phase 22 sites📍 Baltimore📍 Bethesda National Heart, Lung, and Blood Institute (NHLBI) · Tests: Miltenyi CD34 Reagent System, Donor derived G-CSF mobilized PBC Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome NCT03173937Phase 1, Phase 21 site📍 Bethesda National Heart, Lung, and Blood Institute (NHLBI) · Tests: Omidubicel (former CordIn), Miltenyi CliniMACS(R) CD34 Reagent System
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