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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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24 recruiting trials

for Severe Aplastic Anemia (SAA)

CD7 CAR-T Bridging to alloHSCT for Severe Aplastic Anemia NCT06633328EARLY Phase 11 site📍 Hanzhou Zhejiang University · Tests: CD7 CAR-T cells injection, Allogeneic hematopoietic stem cell transplantation TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Non-Malignant Hematological Disorders in Children NCT04356469Phase 21 site📍 St. Petersburg Johns Hopkins All Children's Hospital · Tests: Haploidentical Hematopoietic Cell Transplantation Natural History of Acquired and Inherited Bone Marrow Failure Syndromes NCT05012111n/a1 site📍 Bethesda National Heart, Lung, and Blood Institute (NHLBI) A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) NCT01351545n/a142 sites📍 Birmingham📍 Gilbert📍 Phoenix Center for International Blood and Marrow Transplant Resear… · Tests: A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) Reduced Dose of Cyclophosphamide Combined With Standard Immunosuppressive Therapy to Treat Severe Aplastic Anemia NCT06695741Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Reduced dose of cyclophosphamide combined with standard immunosuppressive therapy Phase I/II Study of Anti-CD38 Monoclonal Antibody in Refractory Severe Aplastic Anemia NCT07714512Phase 1, Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Isatuximab Clinical Study on Modified Allogeneic Hematopoietic Stem Cell Transplantation Regimen for Severe Aplastic Anemia NCT06378060Phase 21 site📍 Kunming Hematology department of the 920th hospital · Tests: Modified transplantation system A Novel Conditioning Regimen for Haplo-HSCT in Older Patients With SAA NCT07586735n/a1 site📍 Beijing Peking University People's Hospital · Tests: BFCA conditiong regimen Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia NCT06517641Phase 225 sites📍 Birmingham📍 Duarte📍 Los Angeles Medical College of Wisconsin · Tests: Haploidentical donor bone marrow transplant, Unrelated donor bone marrow transplant MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure. NCT06412497Phase 21 site📍 Minneapolis Masonic Cancer Center, University of Minnesota · Tests: Rituximab, Rabbit ATG, Cyclophosphamide, Fludarabine, Total Body Irradiation A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic Anemia NCT05757310Phase 11 site📍 Duarte City of Hope Medical Center · Tests: Anti-Thymocyte Globulin, Biospecimen Collection, Bone Marrow Aspirate, Bone Marrow Biopsy, Cyclophosphamide Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis NCT03520647Phase 21 site📍 Bethesda National Heart, Lung, and Blood Institute (NHLBI) · Tests: Cyclophosphamide, Peripheral Blood Stem Cells Peripheral Blood Versus Bone Marrow Plus Peripheral Blood Grafts for Haploidentical Transplantation in Severe Aplastic Anemia NCT07629947NA1 site📍 Beijing Peking University People's Hospital · Tests: G-CSF-Primed Peripheral Blood Stem Cell Graft, G-CSF-Primed Bone Marrow Plus Peripheral Blood Stem Cell Graft Rituximab for Serious Aplastic Anemia With Platelet Transfusion Refractoriness NCT06254560Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Rituximab Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders NCT03579875Phase 21 site📍 Minneapolis Masonic Cancer Center, University of Minnesota · Tests: Total Body Irradiation (TBI) (Plan 1), Cyclophosphamide (CY) (Plan 1), Fludarabine (FLU), Methylprednisolone (MP), Dono… Early Initiation of Oral Therapy With Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA) NCT04304820Phase 21 site📍 Bethesda National Heart, Lung, and Blood Institute (NHLBI) · Tests: Eltrombopag, Cyclosporine, Horse-Anti-thymocyte-Globulin HPC Offered for PRESERVE Expansion NCT07145411n/a4 sites📍 Birmingham📍 Detroit📍 Columbus Ossium Health, Inc. · Tests: Bone Marrow Transplant with Ossium's HPC, Marrow (bone marrow recovered from deceased organ and tissue donors) Dose-attenuated IST and Hetrombopag in Elderly (≥65 Years) Patients With Severe Aplastic Anemia NCT07010237Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Dose-attenuated IST and Hetrombopag CD7 CAR T Cells (RD13-02) in the Treatment of Relapsed/Refractory Severe Aplastic Anemia NCT06622694Phase 11 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: RD13-02 Haploidentical HCT for Severe Aplastic Anemia NCT04558736Phase 21 site📍 Memphis St. Jude Children's Research Hospital · Tests: Anti-Thymocyte Globulin (Rabbit), Fludarabine, Cyclophosphamide, Mesna, G-CSF Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells NCT01174108Phase 22 sites📍 Baltimore📍 Bethesda National Heart, Lung, and Blood Institute (NHLBI) · Tests: Miltenyi CD34 Reagent System, Donor derived G-CSF mobilized PBC Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome NCT03173937Phase 1, Phase 21 site📍 Bethesda National Heart, Lung, and Blood Institute (NHLBI) · Tests: Omidubicel (former CordIn), Miltenyi CliniMACS(R) CD34 Reagent System AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion NCT04099966Phase 21 site📍 Valhalla Mitchell Cairo · Tests: alpha beta depletion Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide for Patients With Severe Aplastic Anemia NCT02828592Phase 22 sites📍 Atlanta📍 Atlanta Northside Hospital, Inc. · Tests: Fludarabine, Cyclophosphamide, Total Body Irradiation, Rabbit ATG, Cyclophosphamide
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