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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Squamous Cell Carcinoma of the Oral Cavity

Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome NCT06380686n/a2 sites๐Ÿ“ Essen๐Ÿ“ Hanover AIO-Studien-gGmbH ยท Tests: data collection Immune Biomarker Study for Cisplatin-ineligible Patients Receiving Chemoradiotherapy With Docetaxel NCT06947668n/a1 site๐Ÿ“ Erlangen University of Erlangen-Nรผrnberg Medical School Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy NCT05793151NA4 sites๐Ÿ“ St Louis๐Ÿ“ Durham๐Ÿ“ Charleston Medical University of South Carolina ยท Tests: ENDURE Proactive Risk-based Optimization & Notifications for Treatment & Outcomes in Head & Neck Cancer NCT07180901NA1 site๐Ÿ“ Montreal Centre hospitalier de l'Universitรฉ de Montrรฉal (CHUM) ยท Tests: Proactive Risk-Based Optimization and Notifications for Treatment and Outcomes (PRONTO) Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer NCT05172245Phase 118 sites๐Ÿ“ Tampa๐Ÿ“ Chicago๐Ÿ“ Fairway National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Ipatasertib Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology NCT02507141n/a5 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Harrison Memorial Sloan Kettering Cancer Center ยท Tests: Reflectance Confocal Microscopy Validity of Viome's Oral/throat Cancer Test NCT06174428n/a2 sites๐Ÿ“ St Louis๐Ÿ“ Memphis Viome ยท Tests: Oral/Throat cancer test Prediction of Malignant Transformation of Oral Leukoplakia Using a MAGE-A-based Immunoscore NCT03975322n/a1 site๐Ÿ“ Erlangen University of Erlangen-Nรผrnberg Medical School Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN) NCT07209189Phase 21 site๐Ÿ“ Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ยท Tests: Toripalimab + Chemotherapy, Toripalimab, Chemoradiotherapy or radiation Evaluating Treatment Strategies for p53 Mutant Oral Cancer and Oral Cancer Precursors NCT07090070NA1 site๐Ÿ“ Vancouver University of British Columbia ยท Tests: Cohort 1 Intervention group, Cohort 2 severe/CIS margins clear, Cohort 2 p53 and severe/CIS margins clear, Cohort 3 Excโ€ฆ TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer NCT06868433Phase 12 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Autologous Tumor Membrane Vesicles Vaccine, Biospecimen Collection, Computed Tomography, Echocardiography, Magnetic Resโ€ฆ Study Comparing Different Neck Treatment Approaches in Patients With Oral Cancer Without Visible Neck Spread NCT07726199NA1 site๐Ÿ“ Kolhฤpur Kolhapur Cancer Centre - Cancer Centers of America ยท Tests: Selective Neck Dissection (Levels I-IV), Intervention : Selective Neck Dissection (Levels I-III) Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer NCT07667400Phase 1, Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: SX-682, DTX Thermotherapy for Head and Neck Cancer Patients NCT07690618Phase 11 site๐Ÿ“ Rotterdam Erasmus Medical Center ยท Tests: Thermotherapy, Radiotherapy, Concurrent chemoradiation RAPA-201 Therapy of Solid Tumors NCT05144698Phase 1, Phase 21 site๐Ÿ“ Hackensack Rapa Therapeutics LLC ยท Tests: RAPA-201 Rapamycin Resistant T Cells, Chemotherapy Prior to RAPA-201 Therapy, Pembrolizumab (PD-1 Blocking Antibody) Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants NCT00898638n/a4 sites๐Ÿ“ Nashville๐Ÿ“ Nashville๐Ÿ“ Nashville Vanderbilt University Medical Center ยท Tests: biologic sample preservation procedure, medical chart review Neoadjuvant Tirellizumab Combined With Chemotherapy for Early Oral Squamous Cell Carcinoma(HNC-SYSU-004) NCT06130332Phase 21 site๐Ÿ“ Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University ยท Tests: PD-1 with chemotherapy, upright surgery Neoadjuvant Immunochemotherapy for LAOSCC NCT06258811Phase 31 site๐Ÿ“ Shanghai Lai-ping Zhong ยท Tests: albumin paclitaxel, cispatin, tislelizumab Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer NCT07195734Phase 2115 sites๐Ÿ“ Tucson๐Ÿ“ Tucson๐Ÿ“ Irvine National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Carboplatin, Cemiplimab, Cisplatin, Computed Tomography Study of TU2218 in Combination With KEYTRUDAยฎ(Pembrolizumab) in Patients With Advanced Solid Tumors NCT05784688Phase 1, Phase 211 sites๐Ÿ“ San Antonio๐Ÿ“ Tyler๐Ÿ“ Spokane TiumBio Co., Ltd. ยท Tests: TU2218 + KEYTRUDAยฎ (Pembrolizumab) Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers NCT00900419n/a1 site๐Ÿ“ Aurora University of Colorado, Denver ยท Tests: immunohistochemistry staining method, laboratory biomarker analysis, sputum cytology, biopsy Enhancing Oral Cancer Awareness NCT06682494NA1 site๐Ÿ“ Richmond Virginia Commonwealth University ยท Tests: Traditional Education, AI-powered Chatbox Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer NCT06532279Phase 2153 sites๐Ÿ“ Gilbert๐Ÿ“ Peoria๐Ÿ“ Phoenix NRG Oncology ยท Tests: Best Practice, Biospecimen Collection, Cisplatin, Computed Tomography, Image Guided Radiation Therapy De-Escalation Postoperative Radiotherapy for Oral Squamous Cell Carcinoma With pCR/MPR. NCT06353685Phase 21 site๐Ÿ“ Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University ยท Tests: Continuous, hyperfractionated, accelerated radiotherapy(CHART) Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination With Paclitaxel in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma, Who Progressed on or After Immune Checkpoint Inhibitor Therapy NCT05283226Phase 213 sites๐Ÿ“ Fullerton๐Ÿ“ Los Angeles๐Ÿ“ Boca Raton NATCO Pharma Ltd. ยท Tests: NRC-2694-A, Paclitaxel Afatinib in Patients With Fanconi Anemia (FA) and Advanced Head and Neck Squamous Cell Carcinoma (HNSCC) NCT06648096Phase 1, Phase 22 sites๐Ÿ“ Hanover๐Ÿ“ Barcelona Fundaciรณ Institut de Recerca de l'Hospital de la Santa Creuโ€ฆ ยท Tests: Afatinib "Ultra-High Frequency intraOral UltraSonography of the TONgue" (HOUSTON) NCT06336941NA1 site๐Ÿ“ Pisa University of Pisa ยท Tests: Ultrasound Study Evaluating the Safety and Feasibility of Panitumumab-IRDye800 and [18F]NOTA-ABY-030 for Targeted Dual-Modality Imaging (TDMI) in Head and Neck Squamous Cell Carcinoma NCT07741643Phase 11 site๐Ÿ“ Nashville Vanderbilt-Ingram Cancer Center ยท Tests: Panitumumab-IRDye800, [18F]NOTA-ABY-030 Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity NCT05791149NA1 site๐Ÿ“ Amiens Centre Hospitalier Universitaire, Amiens ยท Tests: saliva tube SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography NCT06321003n/a1 site๐Ÿ“ Palermo University of Palermo ยท Tests: OCT (Optical Coherence Tomography)
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