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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Stage II Rectal Cancer

SBRT + PD-1 Antibody in Unresectable Locally Recurrent Rectal Cancer๏ผˆSPARKLE๏ผ‰ NCT06767007Phase 21 site๐Ÿ“ Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University ยท Tests: Stereotactic Body Radiation Therapy (SBRT), PD1, Chemotherapy Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer NCT06307548Phase 1, Phase 21 site๐Ÿ“ Buffalo Roswell Park Cancer Institute ยท Tests: Aminolevulinic Acid, Biospecimen Collection, Computed Tomography, Fluorescence-Guided Surgery, Magnetic Resonance Imagiโ€ฆ Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery NCT03051464Phase 2, Phase 34 sites๐Ÿ“ Dallas๐Ÿ“ Montreal๐Ÿ“ Montreal Sir Mortimer B. Davis - Jewish General Hospital ยท Tests: Complete responders and Non-complete responders, Chemoradiation + EBRT Boost, Chemoradiation + HDRBT Boost Sacituzumab Govitecan in Metastatic Colorectal Cancer NCT06243393Phase 2, Phase 31 site๐Ÿ“ Heidelberg University Hospital Heidelberg ยท Tests: Sacituzumab Govitecan (SG), Physicians Choice (PhC). CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors NCT05733000Phase 21 site๐Ÿ“ Chicago Northwestern University ยท Tests: Biospecimen Collection, Computed Tomography, Devimistat, Fluorouracil, Gemcitabine Hydrochloride ROMANCE: "Irinotecan Plus Cetuximab Rechallenge Versus Trifluridine/Tipiracil Plus Bevacizumab in Molecularly Selected Metastatic Colorectal Cancer" NCT07381764Phase 226 sites๐Ÿ“ Alessandria๐Ÿ“ Ancona๐Ÿ“ Aviano Gruppo Oncologico Italia Meridionale ยท Tests: Erbitux (Cetuximab), Bevacizumab, Irinotecan, Trifluridine/tipiracil TT-702 in Patients With Advanced Solid Tumours. NCT05272709Phase 1, Phase 23 sites๐Ÿ“ London๐Ÿ“ Manchester๐Ÿ“ Southampton Cancer Research UK ยท Tests: TT-702, Anti-PD-1 and PD-L1 agent ctDNA Monitoring to Predict the Efficacy of TNT for Rectal Cancer NCT06589388n/a1 site๐Ÿ“ Ho Chi Minh City Gene Solutions Treating Locally Advanced Rectal Cancer With TAS-102 Chemotherapy Plus Neoadjuvant Radiotherapy NCT05965531Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Trifluridine/Tipiracil, intensity-modulated radiotherapy Exploring the Treatment Duration of PD-1 Neoadjuvant Therapy in Stage II-III dMMR Rectal Cancer NCT06613165n/a1 site๐Ÿ“ Xi'an Xijing Hospital Nanoliposomal Irinotecan, Oxaliplatin Plus Capecitabine As Conversion Therapy of Locally Advanced Colorectal Cancer NCT06405139Phase 21 site๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: Nanoliposomal Irinotecan, Oxaliplatin plus Capecitabine Intrafractional Vaginal Dilation in Anal Cancer Patients Undergoing Pelvic Radiotherapy NCT04094454NA1 site๐Ÿ“ Heidelberg Juergen Debus ยท Tests: special tampon with a diameter of 28mm, standard tampon with a diameter of 12-13mm Iparomlimab/Tuvonralimab Integrating With Total Neoadjuvant Therapy for pMMR/MSS Locally Advanced Rectal Cancer (IT-TNT) NCT07026422Phase 21 site๐Ÿ“ Jinan Shandong Cancer Hospital and Institute ยท Tests: Total neoadjuvant therapy integrating iparomlimab/tuvonralimab with chemoradiotherapy Liposomal Irinotecan and Leucovorin/5-fluorouracil Plus Bevacizumab in Metastatic Colorectal Cancer NCT06184698Phase 21 site๐Ÿ“ Shijiazhuang Hebei Medical University Fourth Hospital ยท Tests: liposomal irinotecan, 5-FU, LV, Bevacizumab Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors NCT04165772Phase 210 sites๐Ÿ“ Hartford๐Ÿ“ Miami๐Ÿ“ Basking Ridge Memorial Sloan Kettering Cancer Center ยท Tests: TSR-042 or Dostarlimab, capecitabine or 5-FU, Intensity Modulated Radiation Therapy (IMRT) A Study of HDM2017 Combination Therapy in Advanced Colorectal Cancer NCT07805551Phase 1, Phase 21 site๐Ÿ“ Beijing Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. ยท Tests: HDM2017, Bevacizumab, Oxaliplatin, Fluorouracil, Capecitabine CAPOX and PD-1 Antibody Combined With or Without Radiotherapy for MSS Locally Advanced Rectal Cancer NCT06281405Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: PD-1 inhibitor, Capecitabine, Short-course radiotherapy, Oxaliplatin Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer. NCT06940388Phase 22 sites๐Ÿ“ Mainz๐Ÿ“ Petah Tikva brenner baruch ยท Tests: Tislelizumab, Total neoadjuvant therapy (TNT) Efficacy and Safety of Retlirafusp Alfa Plus Bevacizumab and Chemotherapy With or Without Short-Course Radiotherapy in Patients With CRCLM NCT07728019Phase 21 site๐Ÿ“ Wuhan Union Hospital, Tongji Medical College, Huazhong Universityโ€ฆ ยท Tests: SCRT, Retlirafusp alfa Injection, Bevacizumab, CAPOX KRAS Neoantigen Nanovaccine as Adjuvant Therapy for Colorectal Cancer/Pancreatic Cancer NCT07353645Phase 1, Phase 21 site๐Ÿ“ Nanjing The Affiliated Nanjing Drum Tower Hospital of Nanjing Univeโ€ฆ ยท Tests: KRAS Neoantigen Nanovaccine NOAC9 - Circulating Tumor DNA Guided Follow-Up in Anal Cancer NCT05572801NA13 sites๐Ÿ“ Herlev๐Ÿ“ Vejle๐Ÿ“ Aarhus Aarhus University Hospital ยท Tests: AMR B: HPV positive ctDNA guided imaging in follow-up The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial NCT06565052NA2 sites๐Ÿ“ Boston๐Ÿ“ Boston Dana-Farber Cancer Institute ยท Tests: Prehabilitation Program Partial Liver Segment 2/3 Transplantation Study NCT02215889Phase 1, Phase 21 site๐Ÿ“ Oslo Oslo University Hospital ยท Tests: Liver transplantation Regorafenib and Sintilimab in Combination with Electroacupuncture in MSS CRC NCT06456515NA1 site๐Ÿ“ Changzhou The First People's Hospital of Changzhou ยท Tests: Regorafenib and Sintilimab in combination with electroacupuncture Rectal Cancer CTC Trial NCT07194616NA4 sites๐Ÿ“ Olomouc๐Ÿ“ Olomouc๐Ÿ“ Ostrava University Hospital Ostrava ยท Tests: Primary Surgery, Neoadjuvant radiochemotherapy and surgery RESPONSE: Colorectal Cancer Survivors' Follow-up Care - Now Digital and Need-based NCT06614647NA9 sites๐Ÿ“ Herning๐Ÿ“ Randers๐Ÿ“ Aalborg University of Aarhus ยท Tests: Recurrence monitoring with circulating tumor DNA (ctDNA) as a high risk biomarker, Monitoring for late adverse effects โ€ฆ Intestinal Microbiome Modulation With Antibiotics in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer NCT06793137Phase 21 site๐Ÿ“ Sรฃo Paulo AC Camargo Cancer Center ยท Tests: Metronidazole A Phase II Study of Sintilimab Combined With Ipilimumab N01, Cetuximab and Dabrafenib in Patients With Microsatellite-Stable, BRAF V600E-Mutated Metastatic Colorectal Cancer NCT07506109Phase 24 sites๐Ÿ“ Beijing๐Ÿ“ Wuhan๐Ÿ“ Chengdu Tianjin Medical University Cancer Institute and Hospital ยท Tests: Ipilimumab N01, Sintilimab, Cetuximab, Dabrafenib Different-Dose SCRT Plus CAPOX, PD-1 Blockade and IL-2 in LARC NCT07646639Phase 21 site๐Ÿ“ Nanjing The First Affiliated Hospital with Nanjing Medical Universiโ€ฆ ยท Tests: Sintilimab + IL-2 Combined with CAPOX, Short-course low-dose radiotherapy, Short-course standard-dose radiotherapy Cetuximab Plus Irinotecan in Patients With NeoRAS Wild-type Metastatic Colorectal Cancer In Third-line Therapy NCT05962502Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Cetuximab and irinotecan
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