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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Transformed Lymphoma

Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia NCT05281809Phase 21 site๐Ÿ“ Pittsburgh John Lister ยท Tests: Chimeric Antigen Receptor (CAR) T-Cell Product (Autologous) Testing the Combination of Anti-cancer Drugs Mosunetuzumab, Polatuzumab Vedotin, and Lenalidomide for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma NCT06015880Phase 18 sites๐Ÿ“ Duarte๐Ÿ“ Sacramento๐Ÿ“ Tampa National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Computed Tomography, Lenalidomide, Mosunetuzumab, Polatuzumab Vedotin POLA-R-CHP in the First-line Treatment of Transformed DLBCL NCT06743945Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: POLA-R-CHP Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia NCT03263572Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Blinatumomab, Cytarabine, Methotrexate, Ponatinib Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma NCT05077527Phase 17 sites๐Ÿ“ Duarte๐Ÿ“ Chicago๐Ÿ“ New York AIDS Malignancy Consortium ยท Tests: Axicabtagene Ciloleucel, Cyclophosphamide, Fludarabine Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-T NCT06784726Phase 21 site๐Ÿ“ Seattle University of Washington ยท Tests: Odronextamab, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Chimeric Antigen Receptor T-Cell Therโ€ฆ CD45BE-HSPC + CART-45 Cells NCT07451054Phase 11 site๐Ÿ“ Philadelphia University of Pennsylvania ยท Tests: CART-45 cells, CD45BE-HSPC Treatment of Chinese Participants With B-Cell Malignancies With BGB-16673, a Bruton Tyrosine Kinase-Targeted Protein-Degrader NCT05294731Phase 1, Phase 229 sites๐Ÿ“ Bengbu๐Ÿ“ Hefei๐Ÿ“ Beijing BeOne Medicines ยท Tests: Tacabrutideg Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma NCT06536049Phase 1, Phase 23 sites๐Ÿ“ Minneapolis๐Ÿ“ Columbus๐Ÿ“ Richmond Yazeed Sawalha ยท Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Epcoritamab Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors NCT03934372Phase 1, Phase 223 sites๐Ÿ“ Ghent๐Ÿ“ Paris๐Ÿ“ Paris Incyte Biosciences International Sร rl ยท Tests: Ponatinib Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy NCT06834373Phase 27 sites๐Ÿ“ Scottsdale๐Ÿ“ Jacksonville๐Ÿ“ Albert Lea Mayo Clinic ยท Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Chimeric Antigen Receptor T-Cell Therapy, Computed โ€ฆ HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant NCT03326921Phase 11 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: CD8+ and CD4+ Donor Memory T-cells-expressing HA1-Specific TCR, Bone Marrow Aspiration, Biospecimen Collection Acalabrutinib Maintenance for the Treatment of Patients With Large B-cell Lymphoma NCT05256641Phase 1, Phase 23 sites๐Ÿ“ Los Angeles๐Ÿ“ Sacramento๐Ÿ“ Oklahoma City Jonsson Comprehensive Cancer Center ยท Tests: Acalabrutinib A Phase 1/2 Study of UB-VV400 With Rapamycin in Relapsed/Refractory B-cell Malignancies NCT07735533Phase 1, Phase 21 site๐Ÿ“ Nashville Umoja Biopharma ยท Tests: UB-VV400, Rapamycin (sirolimus) Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy NCT06238648Phase 26 sites๐Ÿ“ Rochester๐Ÿ“ St Louis๐Ÿ“ Hackensack Academic and Community Cancer Research United ยท Tests: Biopsy, Biospecimen Collection, Computed Tomography, Epcoritamab, Magnetic Resonance Imaging A Study of APG-3288 in Relapsed/Refractory Blood Cancers NCT07424833Phase 16 sites๐Ÿ“ Los Angeles๐Ÿ“ Jacksonville๐Ÿ“ Grand Rapids Ascentage Pharma Group Inc. ยท Tests: APG-3288 Odronextamab for the Treatment of Relapsed and Refractory Diffuse Large B-cell Lymphoma Before and After Chimeric Antigen Receptor T-cell Therapy NCT06854159Phase 21 site๐Ÿ“ Sacramento University of California, Davis ยท Tests: Chimeric Antigen Receptor T-Cell Therapy, Odronextamab Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma NCT05633615Phase 295 sites๐Ÿ“ Tucson๐Ÿ“ Tucson๐Ÿ“ Fayetteville SWOG Cancer Research Network ยท Tests: Axicabtagene Ciloleucel, Biospecimen Collection, Computed Tomography, Cyclophosphamide, Fludarabine Epcoritamab Plus Standard of Care Platinum-Based Chemotherapy and Autologous Hematopoietic Cell Transplant for the Treatment of Relapsed or Refractory Large B-cell Lymphoma NCT06905509Phase 21 site๐Ÿ“ Sacramento University of California, Davis ยท Tests: Autologous Hematopoietic Stem Cell Transplantation, Carboplatin, Cytarabine, Dexamethasone, Epcoritamab Study of Safety and Efficacy of TC011 in the Relapsed/Refractory Large B Cell Non-Hodgkin Lymphoma Patients NCT07473167Phase 1, Phase 21 site๐Ÿ“ Seoul TICAROS Co., Ltd. ยท Tests: TC011 Zanubrutinib in Combination With Odronextamab for the Treatment of Patients With Richter's Transformation NCT06735664Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biopsy, Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Echocardiography Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment NCT05890352Phase 2104 sites๐Ÿ“ Tucson๐Ÿ“ Tucson๐Ÿ“ Beverly Hills SWOG Cancer Research Network ยท Tests: Biospecimen Collection, Computed Tomography, Lenalidomide, Magnetic Resonance Imaging, Positron Emission Tomography A Study of NX-1607 in Adults With Advanced Malignancies NCT05107674Phase 117 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ San Francisco Nurix Therapeutics, Inc. ยท Tests: NX-1607, Paclitaxel Zanubrutinib and Lisocabtagene Maraleucel for the Treatment of Richter's Syndrome NCT05873712Phase 23 sites๐Ÿ“ New York๐Ÿ“ Columbus๐Ÿ“ Salt Lake City Aseel Alsouqi ยท Tests: Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Cyclophosphamide, Fludarabine Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances NCT05092451Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Cyclophosphamide, CAR.70/IL15-transduced CB-NK cells, Fludarabine phosphate CC-99282 + Rituximab Early Post CART for Non-Hodgkin's Lymphoma NCT06209619Phase 11 site๐Ÿ“ Columbus Nathan Denlinger ยท Tests: Biopsy, Biospecimen Collection, Computed Tomography, Golcadomide, Positron Emission Tomography Epcoritamab, Rituximab, Gemcitabine and Oxaliplatin (R-GemOx) as Salvage Therapy Before Autologous Stem Cell Transplant for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma NCT07365306Phase 23 sites๐Ÿ“ Duarte๐Ÿ“ Newnan๐Ÿ“ Zion City of Hope Medical Center ยท Tests: Autologous Hematopoietic Stem Cell Transplantation, Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration, Bโ€ฆ Sample Collection for Ongoing Research and Product Evaluation Study - Non-Hodgkin Lymphoma (SCORE-NHL) NCT07750886n/a1 site๐Ÿ“ Austin Natera, Inc. Golcadomide Post-CAR T-cell in R/R Aggressive Large B-cell Lymphoma Patients With High Risk of Relapse NCT06271057Phase 213 sites๐Ÿ“ Crรฉteil๐Ÿ“ Dijon๐Ÿ“ La Tronche The Lymphoma Academic Research Organisation ยท Tests: golcadomide A Phase Ib/II Exploratory Clinical Trial of Memory-Enhanced 7ร—19-THEMIS CAR-T Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma NCT07788118Phase 1, Phase 21 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: 7ร—19-THEMIS CAR-T cells
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