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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Unresectable Metastatic Colorectal Cancer

The Safety and Efficacy of Cetuximab Beta Plus Fruquintinib With or Without Immune Checkpoint Inhibitorrs in First-line Treatment of RAS/BRAF Wild Type Unresectable Metastatic Colorectal Cancer NCT07257653Phase 21 site๐Ÿ“ Hangzhou Zhejiang University ยท Tests: Cetuximab ฮฒ๏ผ›Fruquintinib๏ผ›, Cetuximab ฮฒ๏ผ›Fruquintinib๏ผ›anti-PD1 antibody๏ผ›, Cetuximab ฮฒ๏ผ›Fruquintinib๏ผ›anti-PD1/CTLA4 antibody CT-95 in Advanced Cancers Associated With Mesothelin Expression NCT06756035Phase 19 sites๐Ÿ“ Denver๐Ÿ“ Chicago๐Ÿ“ Grand Rapids Context Therapeutics Inc. ยท Tests: CT-95 COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases NCT06185556Phase 2, Phase 31 site๐Ÿ“ Amsterdam Amsterdam UMC, location VUmc ยท Tests: Irreversible electroporation, Stereotactic body radiotherapy FOLFOX Via HAI Plus Intravenous Irinotecan With or Without Bevacizumab Versus Systemic FOLFOXIRI With or Without Bevacizumab in Initially Unresectable RAS-mutated CRLM Patients NCT05727163Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Dexamethasone, Anisodamine, Oxaliplatin, Leucovorin, Fluorouracil Open-label Phase 1b Study of Ulixertinib and Cetuximab or Ulixertinib in Combination With Cetuximab and Encorafenib in Patients With Unresectable or Metastatic Colorectal Cancer Who Have Previously Received EGFR or BRAF-directed Therapy NCT05985954Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Cetuximab, Ulixertinib, Encorafenib DEBIRI Plus Chemotherapy vs. Chemotherapy Alone in Colorectal Cancer Liver Metastases NCT06555003Phase 31 site๐Ÿ“ Tehran Tehran University of Medical Sciences ยท Tests: Drug-Eluting Embolic Bead, Chemotherapy drug Efficacy and Safety of Chemotherapy With XELOX (Oxaliplatin + Capecitabine) and Bevacizumab in Combination With Adebrelimab in First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer NCT06282445Phase 21 site๐Ÿ“ Jinhua The Fourth Affiliated Hospital of Zhejiang University Schooโ€ฆ ยท Tests: Adebrelimab, Oxaliplatin, Capecitabine, Bevacizumab First-in-human Trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced or Metastatic Colorectal Cancer NCT06934538Phase 1, Phase 29 sites๐Ÿ“ Baltimore๐Ÿ“ Brussels๐Ÿ“ Bordeaux Brenus Pharma ยท Tests: STC-1010 + IS regimen + SOC therapy A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation NCT06778863Phase 121 sites๐Ÿ“ Scottsdale๐Ÿ“ Tucson๐Ÿ“ Los Angeles Clasp Therapeutics, Inc. ยท Tests: CLSP-1025 A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors NCT07488676Phase 1, Phase 221 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ Miami Astellas Pharma Global Development, Inc. ยท Tests: ASP546C Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer NCT07147231Phase 1, Phase 27 sites๐Ÿ“ Aurora๐Ÿ“ Washington D.C.๐Ÿ“ Atlanta National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Cemiplimab, Computed Tomography, Magnetic Resonance Imaging Study of Pembrolizumab Treatment After CYAD-101 With FOLFOX Preconditioning in Metastatic Colorectal Cancer NCT04991948Phase 15 sites๐Ÿ“ Jacksonville๐Ÿ“ Tampa๐Ÿ“ Edegem Celyad Oncology SA ยท Tests: CYAD-101, FOLFOX, Pembrolizumab Cetuximab and Envafolimab Plus mFOLFOXIRI as First-line Treatment for RAS/BRAF Wild-type, MSS, Unresectable Left-side Metastatic Colorectal Cancer NCT05959356Phase 23 sites๐Ÿ“ Foshan๐Ÿ“ Guangzhou๐Ÿ“ Guiyang Sun Yat-sen University ยท Tests: Cetuximab + Envafolimab + mFOLFOXIRI, Cetuximab + mFOLFOX6 Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer NCT06696768Phase 113 sites๐Ÿ“ Gainesville๐Ÿ“ Shiloh๐Ÿ“ Fairway National Cancer Institute (NCI) ยท Tests: Bevacizumab, Biopsy Procedure, Biospecimen Collection, Computed Tomography, Emavusertib Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS) NCT06634875Phase 23 sites๐Ÿ“ Los Angeles๐Ÿ“ Newport Beach๐Ÿ“ Atlanta Buzzard Pharmaceuticals ยท Tests: isunakinra A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors NCT07066657Phase 121 sites๐Ÿ“ Los Angeles๐Ÿ“ San Francisco๐Ÿ“ Aurora ArriVent BioPharma, Inc. ยท Tests: MRG007, MRG007 and Bevacizumab Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients" NCT01365169NA1 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Exercise Intervention, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring Dual-Targeting CAR-NK Cells in Biomarker-Selected Advanced Colorectal Cancer NCT07589517Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: EB-DUO-CAR-NK-CEA/GCC, Lymphodepletion Cadonilimab in Combination With Bevacizumab and FOLFOX Regimen for the First-Line Treatment of Advanced Unresectable MSS-Type, RAS-Mutated Metastatic Colorectal Cancer NCT06218810Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Cadonilimab + bevacizumab + FOLFOX A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors NCT07094204Phase 120 sites๐Ÿ“ Santa Monica๐Ÿ“ Atlanta๐Ÿ“ Jefferson Astellas Pharma Inc ยท Tests: ASP5834, panitumumab Y-90, Capecitabine, and Atezolizumab for Oligometastatic CRC NCT06555133Phase 21 site๐Ÿ“ Providence Brown University ยท Tests: yttrium-90 radioembolization A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations NCT06835569Phase 114 sites๐Ÿ“ Orlando๐Ÿ“ Tampa๐Ÿ“ Boston Alterome Therapeutics, Inc. ยท Tests: ALTA3263, cetuximab, mFOLFOX6, Pembrolizumab, Pemetrexed + Cisplatin /Carboplatin Efficacy and Safety of Combined With Immunotherapy After Induction Therapy With Chemotherapy and Targeted Therapy in the First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer NCT06176885Phase 21 site๐Ÿ“ Jinhua yue junhan ยท Tests: Camrelizumab A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors NCT05592626Phase 1, Phase 219 sites๐Ÿ“ Sacramento๐Ÿ“ Celebration๐Ÿ“ Miami Marengo Therapeutics, Inc. ยท Tests: STAR0602, Irinotecan (Camptosar), Docetaxel (Taxotere) Intermittent or Continuous Panitumumab Plus FOLFIRI for Left Sided RAS/B-RAF Wild-type Metastatic Colorectal Cancer NCT06509126Phase 31 site๐Ÿ“ Naples National Cancer Institute, Naples ยท Tests: Panitumumab, Irinotecan, 5-fluorouracil, L-folinic acid alloSHRINK - Standard cHemotherapy Regimen and Immunotherapy With Allogeneic NKG2D-based CYAD-101 Chimeric Antigen Receptor T-cells NCT03692429Phase 14 sites๐Ÿ“ Tampa๐Ÿ“ Brussels๐Ÿ“ Edegem Celyad Oncology SA ยท Tests: CYAD-101, FOLFOX, FOLFIRI Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases NCT03965234Phase 1, Phase 21 site๐Ÿ“ Buffalo Roswell Park Cancer Institute ยท Tests: Cisplatin, Isolated Chemotherapeutic Lung Perfusion, Metastasectomy Medical Cannabis in Patients With Advanced Pancreatic and Colorectal Cancer NCT06605430Phase 21 site๐Ÿ“ Saint Louis Park HealthPartners Institute ยท Tests: Medical Cannabis The Role of the Tumor Molecular Profile (CMS), UGT1A1 Genotype and Beta-glucuronidase Activity of the Intestinal Microbiota for Treatment Efficiency, Toxicity, Survival and Quality of Life in Patients With Metastatic or Unresectable Colorectal Cancer During Irinotecan-based Systemic Treatment NCT05655780n/a1 site๐Ÿ“ Maastricht Maastricht University Medical Center Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial NCT05863195Phase 362 sites๐Ÿ“ Birmingham๐Ÿ“ Gilbert๐Ÿ“ Phoenix ECOG-ACRIN Cancer Research Group ยท Tests: Bevacizumab, Capecitabine, Cetuximab, Computed Tomography, Floxuridine
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