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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Upper Tract Urothelial Carcinoma

Pembrolizumab and Enfortumab Vedotin With Pembrolizumab Prior to and After Radical Nephroureterectomy for High-Risk Upper Tract Urothelial Cancer NCT05775471Phase 21 site📍 Los Angeles Jonsson Comprehensive Cancer Center · Tests: Biopsy, Biospecimen Collection, Enfortumab Vedotin, MR Urography, Nephroureterectomy A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer NCT06774131Phase 379 sites📍 Homewood📍 Chandler📍 Queen Creek UroGen Pharma Ltd. · Tests: UGN-104 Study of Neoadjuvant Enfortumab Vedotin and Pembrolizumab in Upper Tract Urothelial Cancer NCT06356155Phase 22 sites📍 Ann Arbor📍 Philadelphia University of Michigan Rogel Cancer Center · Tests: Enfortumab vedotin, Pembrolizumab Radiotherapy Combined with Systemic Therapy Versus Systemic Therapy for Oligometastatic UTUCs NCT06652022NA2 sites📍 Beijing📍 Beijing Peking University First Hospital · Tests: Systematic therapy combined with radiotherapy, Systematic drug treatment Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma NCT06262516NA4 sites📍 Gainesville📍 Springfield📍 Cleveland Case Comprehensive Cancer Center · Tests: Nephroureterectomy, Lymph Node Dissection Cisplatin-Based Chemotherapy Followed by Maintenance Avelumab in UTUC NCT07225374Phase 21 site📍 Seoul Samsung Medical Center · Tests: Avelumab 10 mg/kg, Screening, Best Supportive Care (BSC), Follow-up plan Urinary Cell-Free DNA Liquid Biopsy for Urothelial Cancer Diagnosis and Origin Identification NCT07888374n/a1 site📍 Shanghai Ruijin Hospital Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial NCT06764095Phase 41 site📍 Rochester Mayo Clinic · Tests: Biospecimen Collection, Computed Tomography, Cystectomy, Enfortumab Vedotin, Local Therapy Korean Prospective Upper Tract Urothelial Carcinoma Cohort NCT07452432n/a1 site📍 Seoul Samsung Medical Center · Tests: Peripheral blood collection for ctDNA analysis Prospective Validation Study of High Volume Urine DNA Testing in Individuals With Suspicion of Urothelial Cancer NCT06310759n/a8 sites📍 Chicago📍 Vancouver📍 Helsinki Tampere University Hospital Office-Based Ureteroscopy Utilizing a Single Use Digital, Flexible Ureteroscope for Upper Tract Urothelial Carcinoma NCT07630155NA1 site📍 Ann Arbor University of Michigan Rogel Cancer Center · Tests: Analgesic Agent, Electronic Health Record Review, Lidocaine Topical, Medical Device Usage and Evaluation, Survey Admini… Disitamab Vedotin Plus Radiotherapy for Adjuvant Treatment of HER2-Expressing Cisplatin-Ineligible Upper Tract Urothelial Carcinoma NCT07498907Phase 31 site📍 Beijing Peking University First Hospital · Tests: Disitamab Vedotin (RC48), radiotherapy, Gemcitabine (1000 mg/m2), carboplatin Efficacy and Safety of Tislelizumab in Combination With Disitamab-vedotin as Neoadjuvant Therapy for HER2-positive High-risk Upper Tract Urothelial Carcinoma (UTUC) NCT05837806Phase 21 site📍 Tianjin Tianjin Medical University Second Hospital · Tests: tislelizumab+disitamab-vedotin Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer NCT04628767Phase 2, Phase 3258 sites📍 Kingman📍 Fort Smith📍 Little Rock National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Doxorubicin Hydrochloride Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinoma NCT06124976Phase 2, Phase 38 sites📍 Vancouver📍 Winnipeg📍 Halifax Peter Black · Tests: ST-02 Neoadjuvant Gemcitabine Plus Trastuzumab Rezetecan in HER2-positive UTUC NCT07741448Phase 210 sites📍 Huanggang📍 Jingzhou📍 Shiyan Zhiquan Hu · Tests: Trastuzumab Rezetecan, Gemcitabine, Radical nephroureterectomy Research of Double-positive Circulating Cells (Tumor Marker / CD45+) in Several Types of Metastatic Cancers NCT06967961NA1 site📍 Toulouse Institut Claudius Regaud · Tests: For each enrolled patient, the sample described below will be collected as specific intervention intended for research … A Clinical Study of the Efficacy and Safety of Disitamab Vedotin in Combination With Radiotherapy for the Adjuvant Treatment of HER2 Overexpressing UTUC Patients With High Risk Factors for Recurrence After Radical Surgery NCT06210490Phase 21 site📍 Beijing Peking University First Hospital · Tests: Disitamab Vedotin, Radiotherapy, Standard of Care The Danish Bladder Cancer Group 23 Study - A European Study on Cancer in the Upper Urinary Tract NCT07077447n/a5 sites📍 Aarhus N📍 Herlev📍 København Ø Zealand University Hospital · Tests: Kidney sparing surgery for high-risk upper urinary tract urothelial carcinoma Combination of DV and Tislelizumab for Renal Preservation in High-risk UTUC Patients NCT05912816Phase 21 site📍 Shanghai RenJi Hospital · Tests: RC48 Combined With Tislelizumab Combined Postoperative Radiotherapy With Kidney Sparing Surgery for Locally Advanced High-risk Ureteral Cancer NCT06120387n/a2 sites📍 Beijing📍 Beijing Xuesong Li · Tests: Radical surgery, Kidney sparing surgery+Postoperative radiotheray Prognosis of Patients With Upper Tract Urothelial Carcinoma Receiving Kidney-sparing Therapy NCT06204406n/a1 site📍 Shanghai RenJi Hospital · Tests: Observational A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving Trial NCT06040762NA1 site📍 Seattle University of Washington · Tests: Best Practice, Exercise Intervention, App-Based Intervention, App-Based Intervention, Interview POST URS Chemotherapy Instillation NCT06167057NA10 sites📍 Ashdod📍 Beersheba📍 Be’er Ya‘aqov Carmel Medical Center · Tests: Mitomycin/Gemcitabine, Saline Translational Cancer Observational Protocol NCT06169436n/a1 site📍 Milan IRCCS San Raffaele · Tests: Nephroureterectomy Non-invasive Urinary Genomics-Based Risk Assessment for Early Urothelial Carcinoma Diagnosis NCT07614594n/a1 site📍 Zhengzhou Henan Provincial People's Hospital Renal Retention in High Grade Upper Tract Urothelial Cancer NCT05656235Phase 22 sites📍 Washington D.C.📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: Enfortumab vedotin, Pembrolizumab Low-grade UTUC Treated With Nadofaragene Firadenovec Administered to Renal Pelvis NCT06668493Phase 1, Phase 29 sites📍 Scottsdale📍 Santa Monica📍 Jacksonville Ferring Pharmaceuticals · Tests: Nadofaragene Firadenovec uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto NCT05874921n/a22 sites📍 Santa Monica📍 Gainesville📍 Miami UroGen Pharma Ltd. · Tests: Jelmyto (mitomycin) for pyelocalyceal solution Radical Radiotherapy Versus Radical Surgery for UTUC NCT06652009n/a2 sites📍 Beijing📍 Beijing Peking University First Hospital · Tests: Radical nephroureterectomy, Radical radiotherapy
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