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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Uveal Melanoma

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naรฏve Adult Patients With Metastatic Uveal Melanoma NCT06581406Phase 2, Phase 333 sites๐Ÿ“ Scottsdale๐Ÿ“ La Jolla๐Ÿ“ Los Angeles Replimune, Inc. ยท Tests: RP2, Ipilimumab, Nivolumab Dual-Target CSPG4/GD2 CAR-NK Cells for Advanced Melanoma NCT07627698Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: EB-DTKN-401 allogeneic dual-target CSPG4/GD2 CAR-NK cells, Fludarabine, Cyclophosphamide Evaluation of the Safety, Efficacy, and Pharmacokinetics of NBM-BMX in Patients With Metastatic Uveal Melanoma NCT07136181Phase 1, Phase 23 sites๐Ÿ“ Scottsdale๐Ÿ“ Denver๐Ÿ“ Nashville Novelwise Pharmaceutical Corporation ยท Tests: NBM-BMX Capsule are proprietary products developed by Novelwise Pharmaceutical Corporation (Novelwise) for treatment ofโ€ฆ A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas. NCT06022029Phase 116 sites๐Ÿ“ Los Angeles๐Ÿ“ Tamarac๐Ÿ“ Canton OncoNano Medicine, Inc. ยท Tests: ONM-501, Cemiplimab Adjuvant Melatonin for Uveal Melanoma NCT05502900Phase 31 site๐Ÿ“ Stockholm Gustav Stalhammar ยท Tests: Melatonin A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, Dedifferentiated Liposarcoma, or Angiosarcoma NCT05607095Phase 12 sites๐Ÿ“ Harrison๐Ÿ“ New York Memorial Sloan Kettering Cancer Center ยท Tests: Lifileucel (LN-144/LN-145) Neoadjuvant Immunotherapy for Patients With High-risk Eye Melanoma NCT07501117Phase 11 site๐Ÿ“ Herlev Inge Marie Svane ยท Tests: Nivolumab & Ipilimumab ACTengineยฎ IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors NCT03686124Phase 1, Phase 221 sites๐Ÿ“ Stanford๐Ÿ“ Aurora๐Ÿ“ Miami Immatics US, Inc. ยท Tests: IMA203 Product, IMA203 product- flat dose, IMA203CD8 Product, Nivolumab, IMADetectยฎ Neoadjuvant Tebentafusp for Uveal Melanoma NCT06414590Phase 22 sites๐Ÿ“ Philadelphia๐Ÿ“ Philadelphia Thomas Jefferson University ยท Tests: Tebentafusp-Tebn Immune Response to Percutaneous Hepatic Perfusion With Melphalan for Ocular Melanoma Metastatic to the Liver NCT07364474NA1 site๐Ÿ“ Boston Massachusetts General Hospital ยท Tests: Melphalan through Percutaneous Hepatic Perfusion, Melphalan through Percutaneous Hepatic Perfusion in combination with โ€ฆ Observational Study of Iris Tumors NCT03809585n/a1 site๐Ÿ“ Portland Oregon Health and Science University Adjuvant Tebentafusp in High Risk Ocular Melanoma NCT06246149Phase 315 sites๐Ÿ“ Lake Success๐Ÿ“ Brussels๐Ÿ“ Nice European Organisation for Research and Treatment of Cancer โ€ฆ ยท Tests: Tebentafusp MAGE-C2 TCR T Cell Trial to Treat Melanoma and Head and Neck Cancer NCT04729543Phase 1, Phase 21 site๐Ÿ“ Rotterdam Erasmus Medical Center ยท Tests: Adoptive therapy with autologous MC2 TCR T cells Study of Adjuvant Darovasertib and Crizotinib in Participants With Primary Non-metastatic Uveal Melanoma NCT07804186Phase 313 sites๐Ÿ“ Scottsdale๐Ÿ“ Los Angeles๐Ÿ“ Boston IDEAYA Biosciences ยท Tests: Darovasertib, Crizotinib (Xalkori) Neoadjuvant Darovasertib in Primary Uveal Melanoma NCT07015190Phase 394 sites๐Ÿ“ Scottsdale๐Ÿ“ La Jolla๐Ÿ“ Los Angeles IDEAYA Biosciences ยท Tests: Darovasertib, Primary Local Therapy Tebentafusp and Roginolisib in Uveal Melanoma to Prolong T-cell Homeostasis NCT07203391Phase 12 sites๐Ÿ“ Sydney๐Ÿ“ Melbourne St Vincent's Hospital, Sydney ยท Tests: roginolisib Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome NCT04792463n/a1 site๐Ÿ“ Columbus Mohamed Abdel-Rahman Identification of New Candidate Genes for Hereditary Predisposition to Uveal Melanoma NCT06550674NA1 site๐Ÿ“ Clermont-Ferrand Centre Jean Perrin ยท Tests: Constitutional exome analysis Resistance Exercise in Patients With Ocular Melanoma NCT06970236NA1 site๐Ÿ“ Valencia University of Valencia ยท Tests: Exercise A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit NCT06805825Phase 15 sites๐Ÿ“ Ann Arbor๐Ÿ“ Cleveland๐Ÿ“ Portland Novelty Nobility, Inc. ยท Tests: NN3201 A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body NCT06413680Phase 1, Phase 211 sites๐Ÿ“ Los Angeles๐Ÿ“ San Francisco๐Ÿ“ North Haven Regeneron Pharmaceuticals ยท Tests: REGN10597, Cemiplimab Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma NCT06121180Phase 24 sites๐Ÿ“ Los Angeles๐Ÿ“ Tampa๐Ÿ“ Chicago H. Lee Moffitt Cancer Center and Research Institute ยท Tests: ZIV-Aflibercept, Cemiplimab Adding IL-2 to Tebentafusp to Eradicate Cancer Progression NCT07063875Phase 1, Phase 22 sites๐Ÿ“ Sydney๐Ÿ“ Melbourne St Vincent's Hospital, Sydney ยท Tests: Aldesleukin Retrospective Register for Uveal Melanoma NCT05733728n/a1 site๐Ÿ“ Vienna Medical University of Vienna ยท Tests: any therapy suitable Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors NCT04119024Phase 13 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Stanford Anusha Kalbasi ยท Tests: Biopsy, Biospecimen Collection, Computed Tomography, Cyclophosphamide, Fludarabine Phosphate Follow-up of Patients With Uveal Melanoma Adapted to the Risk of Relapse (SALOME) NCT04424719NA1 site๐Ÿ“ Paris Institut Curie ยท Tests: Blood test Assessing the Clinical Effectiveness of Serum Biomarkers in the Diagnosis of Metastatic Uveal Melanoma NCT01438658n/a1 site๐Ÿ“ Jerusalem Hadassah Medical Organization A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel NCT06940739Phase 1, Phase 25 sites๐Ÿ“ Denver๐Ÿ“ Chapel Hill๐Ÿ“ Nashville Iovance Biotherapeutics, Inc. ยท Tests: IOV-3001 Safety and Preliminary Efficacy of MBS8(1V270) in Cancer Patients With Advanced Solid Tumours NCT04855435Phase 15 sites๐Ÿ“ Herlev๐Ÿ“ Barcelona๐Ÿ“ Madrid MonTa Biosciences ApS ยท Tests: MBS8(1V270), MBS8(1V270) and pembrolizumab combination Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions NCT03947385Phase 1, Phase 215 sites๐Ÿ“ Los Angeles๐Ÿ“ San Francisco๐Ÿ“ Denver IDEAYA Biosciences ยท Tests: IDE196, Binimetinib, Crizotinib
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