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An autosomal dominant inherited syndrome caused by mutations in the BRCA1 or BRCA2 genes. Patients are at high risk of developing breast cancer, particularly before the age of fifty, high risk of developing a second primary breast cancer, and high risk of developing both breast and ovarian cancer.
Breast cancer is a cancer that starts in breast tissue. It happens when cells in the breast change and grow out of control. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor.
Sometimes the cancer does not spread any further. This is called "in situ." If the cancer spreads outside the breast, the cancer is called "invasive." It may just spread to nearby tissues and lymph nodes. Or the cancer may metastasize (spread to other parts of the body) through the lymph system or the blood.
Breast cancer is the second most common type of cancer in women in the United States. Rarely, it can also affect men.
From MedlinePlus: Breast Cancer (US National Library of Medicine) ↗
🧬 Cancer: Cancer is a group of diseases in which some of the body's cells grow and divide without control, and can spread to other parts of the body.
General information about cancer, reviewed by people; it does not describe any one person. Below: the evidence for hereditary breast ovarian cancer syndrome itself.
AI reads the targets, drugs, trials and papers below and writes where the science stands — every claim cited. It is shared with everyone who opens hereditary breast ovarian cancer syndrome.
Green labels: what the target is known to be druggable by. The score combines genetics, somatic mutations, drugs, expression and literature.
No drugs recorded yet.
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