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Asthma: the latest breakthroughs

Everything that changed in the last year, from three public sources: phase 3 trials that posted their results, papers in the leading medical and cancer journals, and US drug labels that were updated. Refreshed every week.

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What changed

Written by AI from the evidence below, every point cited

AI reads the results, papers and label updates below and explains what changed and why it matters, citing each source. It is shared with everyone.

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Phase 3 results posted

The large trials that decide new standard treatments · ClinicalTrials.gov
A Study to Assess and Compare Safety and Tolerability of 3 Months Treatment With Salbutamol Administered Via MDI Containing Propellant HFA-152a or HFA-134a in Participants ≥ 18 Years of Age With AsthmaNCT06261957 · results posted 2026-10-06 · GlaxoSmithKline · 471 people · tests Salbutamol HFA-134a, Salbutamol HFA-152a Foster 100/6 mg NEXThaler Versus Foster 100/6mg Pressurized Metered-dose Inhaler (pMDI) in Patients With Controlled Asthma.NCT03453112 · results posted 2026-08-10 · Chiesi Farmaceutici S.p.A. · 494 people · tests Foster 100/6µg NEXThaler, Foster 100/6µg pMDI A Study Evaluating the Efficacy and Safety of Lebrikizumab in Adult Patients With Mild to Moderate AsthmaNCT02104674 · results posted 2026-07-17 · Hoffmann-La Roche · 313 people · tests Lebrikizumab, Montelukast, Placebo A Study of Lebrikizumab in Participants With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Second Controller MedicationNCT01867125 · results posted 2026-07-17 · Hoffmann-La Roche · 1081 people · tests Lebrikizumab, Placebo Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (LOGOS)NCT04609904 · results posted 2026-07-02 · AstraZeneca · 2187 people · tests BGF MDI 320/28.8/9.6 μg, BGF MDI 320/14.4/9.6 μg, BFF MDI 320/9.6 μg, BFF pMDI 320/9 μg Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (KALOS)NCT04609878 · results posted 2026-06-30 · AstraZeneca · 2274 people · tests BGF MDI 320/28.8/9.6 μg, BGF MDI 320/14.4/9.6 μg, BFF MDI 320/9.6 μg, BFF pMDI 320/9 μg A Study of Lebrikizumab in Adolescent Participants With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Second Controller MedicationNCT01875003 · results posted 2026-06-30 · Hoffmann-La Roche · 346 people · tests Lebrikizumab, Placebo, Standard of Care TRIple in asthMA With uncontRolled pAtient on Medium streNgth of ICS + LABANCT02676076 · results posted 2026-06-26 · Chiesi Farmaceutici S.p.A. · 1155 people · tests CHF 5993 100/6/12.5, CHF 1535 100/6 µg AZithromycin Therapy in Preschoolers With a Severe Wheezing Episode Diagnosed at the Emergency DepartmentNCT04669288 · results posted 2026-06-23 · University of Arizona · 840 people · tests Azithromycin, Placebo Tezepelumab Efficacy and Safety in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent AsthmaNCT05398263 · results posted 2026-06-18 · AstraZeneca · 125 people · tests Tezepelumab, Placebo TRIple in Asthma hiGh strenGth vErsus Ics/Laba hs and tiotRopium (TRIGGER)NCT02676089 · results posted 2026-05-29 · Chiesi Farmaceutici S.p.A. · 1437 people · tests CHF 5993 200/6/12.5 µg, CHF 1535 200/6 µg, CHF 1535 200/6 µg + Tiotropium Respimat 2.5 µg A Study of GSK3511294 (Depemokimab) Compared With Mepolizumab or Benralizumab in Participants With Severe Asthma With an Eosinophilic PhenotypeNCT04718389 · results posted 2026-05-18 · GlaxoSmithKline · 1717 people · tests GSK3511294 (Depemokimab), Mepolizumab, Benralizumab, Placebo

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