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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced or Recurrent Solid Tumors

COAST Therapy in Advanced Solid Tumors and Prostate Cancer NCT05036226Phase 1, Phase 21 site๐Ÿ“ Charleston Medical University of South Carolina ยท Tests: Hydroxychloroquine, Metformin, Sirolimus, Hydroxychloroquine, Metformin, Sirolimus, Dasatanib, Hydroxychloroquine, Metfโ€ฆ Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study NCT07405086Phase 41 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Biospecimen Collection, Immune Checkpoint Inhibitor Talazoparib and Palbociclib, Axitinib, or Crizotinib for the Treatment of Advanced or Metastatic Solid Tumors, TalaCom Trial NCT04693468Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Axitinib, Crizotinib, Palbociclib Isethionate, Talazoparib Tosylate CT-95 in Advanced Cancers Associated With Mesothelin Expression NCT06756035Phase 19 sites๐Ÿ“ Denver๐Ÿ“ Chicago๐Ÿ“ Grand Rapids Context Therapeutics Inc. ยท Tests: CT-95 Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors NCT04777994Phase 130 sites๐Ÿ“ Tucson๐Ÿ“ New Haven๐Ÿ“ Baltimore Calico Life Sciences LLC ยท Tests: ABBV-CLS-484, Vascular Endothelial Growth Factor Receptor (VEGFR) Tyrosine Kinase Inhibitor (TKI), Programmed Cell Deatโ€ฆ Safety and Modulation of Adaptive Immunity by Iscadorยฎ Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors NCT06408688Phase 44 sites๐Ÿ“ Baden๐Ÿ“ Basel๐Ÿ“ Liestal University Hospital, Basel, Switzerland ยท Tests: Immune checkpoint inhibitors plus Iscadorยฎ Qu., Immune Checkpoint Inhibitors Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors NCT06320405Phase 1, Phase 21 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Axatilimab, Biopsy, Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging ML-016 in Advanced Cancer With Lung and/or Liver Involvement NCT07723482Phase 1, Phase 23 sites๐Ÿ“ Miranda๐Ÿ“ Wollongong๐Ÿ“ Buderim BrYet US, Inc. ยท Tests: ML-016 A Study of SR-8541A (ENPPI Inhibitor) in Advanced/Metastatic Solid Tumors NCT06063681Phase 13 sites๐Ÿ“ Randwick๐Ÿ“ Clayton๐Ÿ“ Frankston Stingray Therapeutics ยท Tests: SR-8541A, Immune checkpoint inhibitor (ICI) IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors NCT05039801Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Bevacizumab, Glutaminase-1 Inhibitor IACS-6274, Paclitaxel, Capivasertib Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors NCT05270213Phase 114 sites๐Ÿ“ Scottsdale๐Ÿ“ Tucson๐Ÿ“ Palo Alto Riboscience, LLC. ยท Tests: RBS2418, Pembrolizumab, Other approved anti-cancer therapy APG-2449 Monotherapy or in Combination With PLD in Patients With Platinum-resistant Recurrent OC or Advanced ST NCT06687070Phase 11 site๐Ÿ“ Guangzhou Ascentage Pharma Group Inc. ยท Tests: APG -2449, PLD A Study of ONO-7429 in Participants With Unresectable Advanced or Recurrent Solid Tumors NCT07787208Phase 110 sites๐Ÿ“ Kashiwa๐Ÿ“ Maebashi๐Ÿ“ Niigata Ono Pharmaceutical Co., Ltd. ยท Tests: ONO-7429 Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors NCT06132503Phase 11 site๐Ÿ“ West Valley City Lantern Pharma Inc. ยท Tests: LP-284 Combination of CAR-DC Vaccine and ICIs in Malignant Tumors NCT05631886Phase 11 site๐Ÿ“ Beijing Chinese PLA General Hospital ยท Tests: TP53-EphA-2-CAR-DC, Abraxane, Cyclophosphamide, anti-PD-1 antibody, Anti-CTLA4 Monoclonal Antibody Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients With Advanced, Refractory or Recurrent Solid Tumors NCT06234098Phase 1, Phase 29 sites๐Ÿ“ Scottsdale๐Ÿ“ Bakersfield๐Ÿ“ El Segundo Alyssum Therapeutics ยท Tests: AT-1965 Liposome Injection SSGJ-705 Monotherapy and Combination Therapy in Advanced HER2-Expressing Solid Tumors NCT07022002Phase 21 site๐Ÿ“ Hangzhou Shenyang Sunshine Pharmaceutical Co., LTD. ยท Tests: SSGJ-705, PD-1/L1 inhibitor combined with chemotherapy, SSGJ-705 combined with chemotherapy Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors NCT05533697Phase 1, Phase 239 sites๐Ÿ“ Los Angeles๐Ÿ“ San Francisco๐Ÿ“ Aurora ModernaTX, Inc. ยท Tests: mRNA-4359, Pembrolizumab, Ipilimumab, Nivolumab A Dose Escalation and Expansion Study of [177Lu]Lu-SN201 in Participants With Advanced Cancer NCT06184035Phase 1, Phase 22 sites๐Ÿ“ Adelaide๐Ÿ“ Melbourne Spago Nanomedical AB ยท Tests: [177Lu]Lu-SN201 Study of ACR-2316 in Specific Advanced Solid Tumors NCT06667141Phase 1, Phase 215 sites๐Ÿ“ Phoenix๐Ÿ“ Beverly Hills๐Ÿ“ Newport Beach Acrivon Therapeutics ยท Tests: ACR-2316 A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors NCT04775485Phase 235 sites๐Ÿ“ San Francisco๐Ÿ“ Washington D.C.๐Ÿ“ Chicago Day One Biopharmaceuticals, Inc. ยท Tests: Tovorafenib Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer NCT05098210Phase 11 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Neoantigen Peptide Vaccine, Nivolumab, Poly ICLC, Echocardiography Test, Multigated Acquisition Scan A Study of XB628 Alone and in Combination With Zanzalintinib in Participants With Recurrent Advanced or Metastatic Solid Tumors NCT06952010Phase 111 sites๐Ÿ“ San Francisco๐Ÿ“ New Haven๐Ÿ“ Tampa Exelixis ยท Tests: XB628, Zanzalintinib A Study Evaluating the Immunotherapy Treatment for Ovarian Cancer and Other Advanced Malignancies. NCT07389239Phase 1, Phase 21 site๐Ÿ“ Chicago University of Chicago ยท Tests: Decitabine, Cyclophosphamide Conditioning, NY-ESO-1 TCR/ dnTGFฮฒRII, Aldesleukin Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatment NCT02029001Phase 27 sites๐Ÿ“ Bordeaux๐Ÿ“ Lyon๐Ÿ“ Lyon Centre Leon Berard ยท Tests: Nilotinib (400 mg BID), Everolimus (10 mg QD), Sorafenib (400 mg BID), Lapatinib (1500 mg QD), Pazopanib (800 mg QD) Parenting Support Intervention for Families Coping With Metastatic or Locally Recurrent Solid Tumor Diagnosis NCT05059678NA1 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Best Practice, Educational Intervention, Questionnaire Administration A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression NCT06682793Phase 1, Phase 210 sites๐Ÿ“ Gilbert๐Ÿ“ La Jolla๐Ÿ“ Los Angeles A2 Biotherapeutics Inc. ยท Tests: A2B395, xT CDx with HLA-LOH assay A Phase 1, Open-Label, Dose-Escalation Study to Evaluate Safety, Tolerability, and Clinical Activity of CBX-663 in Participants With Relapsed or Refractory Myeloid Malignancies, Advanced Solid Tumors, or Recurrent or Progressive Glioblastoma. NCT07779798Phase 14 sites๐Ÿ“ Duarte๐Ÿ“ Tampa๐Ÿ“ Houston Crossbow Therapeutics, Inc. ยท Tests: CBX-663 BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study NCT05136196Phase 2232 sites๐Ÿ“ Phoenix๐Ÿ“ Little Rock๐Ÿ“ Beverly Hills National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Cabozantinib S-malate, Computed Tomography, Magnetic Resonance Imaging A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression NCT06051695Phase 1, Phase 212 sites๐Ÿ“ Gilbert๐Ÿ“ La Jolla๐Ÿ“ Los Angeles A2 Biotherapeutics Inc. ยท Tests: A2B694, A2B543, xT CDx with HLA-LOH Assay
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