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19 recruiting trials

for Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Upper Airway Inflammation and Olfaction: Mechanisms of Loss and Recovery NCT06776042NA1 site๐Ÿ“ Brussels Cliniques universitaires Saint-Luc- Universitรฉ Catholique dโ€ฆ ยท Tests: Nasal brushing of the olfactory cleft, Smell testing Metabolic and Immunologic Biomarkers in Chronic Rhinosinusitis With Nasal Polyps NCT07860411n/a1 site๐Ÿ“ Sanliurfa Harran University ยท Tests: Nasal polyp tissue and blood sampling, Nasal mucosa and blood sampling Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients. NCT06892704n/a1 site๐Ÿ“ Chicago Northwestern University ยท Tests: Dupilumab - Standard Dose Real Life Study of Biologicals in Patients With Severe CRSwNP NCT05938972n/a1 site๐Ÿ“ Ghent University Hospital, Ghent ยท Tests: Mepolizumab Effect of Dupilumab on Nasal Epithelial Barrier Function in Patients With CRSwNP NCT06398873n/a1 site๐Ÿ“ Vienna Medical University of Vienna ยท Tests: Dupilumab 300 MG/2 ML Subcutaneous Solution [DUPIXENT] Prospective, Non-interventional Single-arm Study With Tezepelumab to Investigate the Change in Clinical and Patient-reported Outcomes in Patients With CRSwNP in Real-world (PETRICHOR) NCT07633158n/a19 sites๐Ÿ“ Berlin๐Ÿ“ Bochum๐Ÿ“ Braunschweig AstraZeneca A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP) NCT06338995Phase 3202 sites๐Ÿ“ Birmingham๐Ÿ“ Birmingham๐Ÿ“ Huntsville Eli Lilly and Company ยท Tests: LY3650150, Placebo, Standard therapy for INCS A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) NCT07782957Phase 34 sites๐Ÿ“ Sherman Oaks๐Ÿ“ Greenville๐Ÿ“ Plano GlaxoSmithKline ยท Tests: GSK5784283, Placebo, Standard of Care Interleukin-4Ra Blockade by Dupilumab Decreases Staphylococcus Colonization and Increases Microbial Diversity in CRSwNP NCT05094570Phase 41 site๐Ÿ“ Charlottesville University of Virginia ยท Tests: Dupilumab Prefilled Syringe Real-life Evaluation of the Efficacy of Biologicals in Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP) NCT06683261n/a8 sites๐Ÿ“ Aalst๐Ÿ“ Bruges๐Ÿ“ Brussels Universitaire Ziekenhuizen KU Leuven ยท Tests: Omalizumab, Dupilumab, Mepolizumab 100 mg A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) NCT07782970Phase 33 sites๐Ÿ“ Los Angeles๐Ÿ“ Tulsa๐Ÿ“ San Juan GlaxoSmithKline ยท Tests: GSK5784283, Placebo, Standard of Care Clinical Trial of TQC2731 Injection in Patients With Chronic Sinusitis and Nasal Polyps NCT07107256Phase 360 sites๐Ÿ“ Fuyang๐Ÿ“ Hefei๐Ÿ“ Beijing Shanghai Chia Tai Tianqing Pharmaceutical Technology Develoโ€ฆ ยท Tests: TQC2731 injection, Placebo of TQC2731 Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training NCT07681973NA1 site๐Ÿ“ Cleveland The Cleveland Clinic ยท Tests: Smell Training A Study of BBT002 in Healthy Volunteers (HVs) and in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) With or Without Comorbid Asthma NCT07436949Phase 1, Phase 212 sites๐Ÿ“ Beijing๐Ÿ“ Guangzhou๐Ÿ“ Changsha Bambusa Therapeutics ยท Tests: BBT002, Placebo A Study to Investigate NPS and Symptoms in Chinese Adult Participants With CRSwNP Initiating Treatment With Tezepelumab NCT07520162Phase 334 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Bengbu AstraZeneca ยท Tests: Tezepelumab Real-Time Diagnosis of Eosinophilic Nasal Polyps Using High-Sensitivity Spectroscopy NCT07125586NA1 site๐Ÿ“ Qingdao The Affiliated Hospital of Qingdao University ยท Tests: High-Sensitivity Spectroscopy with Autofluorescence for eCRSwNP Diagnosis ReAl-woRld Evaluation of tEzepelumab for Chronic rhinoSinusitis With Nasal Polyps in Russia NCT07399665n/a10 sites๐Ÿ“ Kazan'๐Ÿ“ Kemerovo๐Ÿ“ Krasnoyarsk AstraZeneca Efficacy and Safety of Depemokimab Monotherapy Without Concomitant Use of Intranasal Corticosteroids (INCS) in Japanese Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) NCT07701967Phase 410 sites๐Ÿ“ Ehime๐Ÿ“ Ehime๐Ÿ“ Fukui GlaxoSmithKline ยท Tests: Depemokimab Implementation of a Joint Pulmonologist and ENT Consultation in the Care Pathway of Patients Suffering From Asthma and Chronic Rhinosinusitis With Nasal Polyposis: Effectiveness Compared With Consultations by Specialty (CON-PO Study). NCT07134686NA1 site๐Ÿ“ Marseille Assistance Publique Hopitaux De Marseille ยท Tests: Joint consultation, Mucus sampling, Nasal brushing
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