🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

🧪

Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

30 recruiting trials

for Depression / Major Depressive Disorder

Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study NCT06897670n/a1 site📍 Rochester Mayo Clinic · Tests: Observational assessment using functional near-infrared spectroscopy (fNIRS), a noninvasive, portable brain imaging too… The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. NCT05973851Phase 312 sites📍 Innsbruck📍 Bielefeld📍 Dortmund Dr. Inge Winter · Tests: Esketamine Nasal Product, Ketamine Hydrochloride, Esketamine hydrochloride, Second-line Antidepressants Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure NCT05603104Phase 31 site📍 Ramat Gan Dr. Inge Winter · Tests: Clozapine, Esketamine Nasal Product, Escitalopram, Sertraline, Venlafaxine Triage Survey for Psychiatry Research Eligibility NCT05800925n/a6 sites📍 Boston📍 Watertown📍 New York Adams Clinical · Tests: Survey Resolving Early Life Stress: Psychotherapy Outcomes and Neurobiology in Complex Depression NCT07250893NA1 site📍 Hamilton St. Joseph's Healthcare Hamilton · Tests: Psychotherapy Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression NCT07226232Phase 35 sites📍 Birmingham📍 Tuscaloosa📍 Portland VA Office of Research and Development · Tests: Psilocybin, Psilocybin Meditative Neurofeedback for Depression NCT06675240Phase 11 site📍 La Jolla University of California, San Diego · Tests: MediNF, ShamMediNF A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms NCT06223880Phase 440 sites📍 Bellflower📍 Lafayette📍 Oceanside Axsome Therapeutics, Inc. · Tests: AXS-05, Bupropion Neural Correlates of Stress and Perceived Control in Adolescent Depression NCT04788524NA1 site📍 Belmont Mclean Hospital · Tests: Computer Task Manipulation University of Iowa Interventional Psychiatry Service Patient Registry NCT04480918n/a1 site📍 Iowa City Mark Niciu · Tests: Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (TMS), Ketamine, Esketamine, Deep Transcranial Magne… Neuromodulation and Attention Deficits in MDD NCT07111169NA1 site📍 Chengdu University of Electronic Science and Technology of China · Tests: intermittent theta burst stimulation (iTBS) intervention The Cerebral and Cognitive Changes After Intermittent Theta Burst Stimulation (iTBS) Treatment for Depression NCT06534684NA1 site📍 Tromsø University Hospital of North Norway · Tests: Intermittent Theta Burst Stimulation Identifying Local Field Potential Biomarkers for Treatment-Resistant Major Depression With Deep Brain Stimulation NCT06542094NA1 site📍 Chengdu West China Hospital · Tests: Deep Brain stimulation Validation of the CIDI 5.0 Against the SCID-5 for Lifetime Mental Disorders NCT07604753n/a1 site📍 Hong Kong The University of Hong Kong · Tests: CIDI-5 A Randomized Neuroimaging Trial of Psilocybin in Depression NCT06072898Phase 21 site📍 Toronto Sunnybrook Health Sciences Centre · Tests: Psilocybin, Microcrystalline cellulose, Supportive psychotherapy Singula Phase 0.1 Primary Care Pilot NCT07834684n/a2 sites📍 Brentwood📍 Mount Kisco Singula Health, Inc. Aerobic Versus Leisure Group for Adolescents With Depression NCT05076214NA4 sites📍 Halmstad📍 Stockholm📍 Stockholm Lund University Hospital · Tests: Aerobic exercise in group, Leisure activities in group Evaluation of Deep Brain Stimulation (DBS) of the Right Operculum 3 (OP3) in Permanent Non-pulsatile Disabling Tinnitus (TINNOP3-DBS) NCT04296097NA1 site📍 Grenoble University Hospital, Grenoble · Tests: DBS Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality NCT05925322NA1 site📍 New York Weill Medical College of Cornell University · Tests: "Engage & Connect" Psychotherapy, Symptom Review and Psychoeducation (SRP) Brain Imaging of Cognition Inn Schizophrenia and Depression NCT04159662n/a1 site📍 Ottawa The Royal Ottawa Mental Health Centre Accelerated Treatment of Depressive Patients With tDCS NCT07444242NA1 site📍 Regensburg University of Regensburg · Tests: Transcranial direct current stimulation RCT of At-Home tDCS for Depression in Pregnancy NCT05097586NA2 sites📍 Toronto📍 Toronto Women's College Hospital · Tests: active tDCS, workbook, sham tDCS Peripheral Neuroimmune Mechanisms of Hyperthermia NCT05366270NA1 site📍 Boston Massachusetts General Hospital · Tests: WBH, Sham Double-blind, Placebo-controlled Study in Adults With Major Depressive Disorder NCT07226661Phase 21 site📍 Garden Grove Supernus Pharmaceuticals, Inc. · Tests: SPN-821 2400 mg, Placebo Reward-specific Changes of the Chemical Messenger Dopamine in the Brain of Healthy and Depressed People NCT06675851Phase 41 site📍 Vienna Medical University of Vienna · Tests: WELLBUTRIN SR (Bupropion HCI) Sustained-Release Tablets, 150 mg; GlaxoSmithKline, Cipralex (escitalopram) Health and Work Ability Following Inpatient Treatment for Stress-related Disorders - Follow-up Study of the HARMODI Cohort NCT07757997n/a2 sites📍 Süs📍 Süs Clinica Holistica Engiadina Transdiagnostic Internet-delivered Intervention for Adolescents With Anxiety and Depression NCT06724666NA2 sites📍 Cluj-Napoca📍 Cluj-Napoca Babes-Bolyai University · Tests: Transdiagnostic Internet-delivered intervention A Randomized, Open-Label, 52-Week Extension Study to Evaluate the Maintenance of Remission, Relapse Prevention, and Long-Term Safety of CreNeuroS™ in Patients With Major Depressive Disorder Who Achieved Remission Following an 8-Week Parent Study NCT07893002NA1 site📍 Vadodara Sichuan Credit Pharmaceutical Co., Ltd. · Tests: No intervention, CreNeuroS™ CNS Fish Oil Plus Softgels, 1 capsule orally once daily, CreNeuroS™ CNS Fish Oil Plus Softg… A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression NCT07300969Phase 243 sites📍 Bentonville📍 Little Rock📍 Oceanside Draig Therapeutics Ltd · Tests: DT-101, DT-101, Placebo Non-invasive BCI and Application Verification for Depressed People NCT06417437Phase 41 site📍 Shanghai Shanghai Mental Health Center · Tests: SSRI, rTMS, Neuro-Feedback, Game Regulation
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy