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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Epilepsy, Generalized

Repertoire and Properties of Anti-drug Antibodies Involved in Immediate Hypersensitivity in the Operating Room NCT05420935NA1 site๐Ÿ“ Paris Assistance Publique - Hรดpitaux de Paris ยท Tests: IgG group, IgE group, IgG group + IgE group Registry and Natural History Study for Progressive Myoclonus Epilepsy Type 1 (EPM1) NCT06593951n/a1 site๐Ÿ“ Boston Boston Children's Hospital ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome NCT07531745Phase 1, Phase 26 sites๐Ÿ“ Ann Arbor๐Ÿ“ Rochester๐Ÿ“ Durham Ionis Pharmaceuticals, Inc. ยท Tests: ION337 A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures NCT05667142Phase 3138 sites๐Ÿ“ Mobile๐Ÿ“ Phoenix๐Ÿ“ Tucson Xenon Pharmaceuticals Inc. ยท Tests: XEN1101, Placebo Ketogenic Diet for New-Onset Absence Epilepsy NCT04274179Phase 31 site๐Ÿ“ Baltimore Johns Hopkins University ยท Tests: Modified Atkins Diet, Absence epilepsy medications Biology of Juvenile Myoclonic Epilepsy NCT03400371n/a15 sites๐Ÿ“ New York๐Ÿ“ New York๐Ÿ“ Columbus King's College London ยท Tests: Blood draw, Existing samples An Open Label Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adults With Focal Onset or Tonic-Clonic Seizures NCT06908356Phase 211 sites๐Ÿ“ Phoenix๐Ÿ“ Miami Lakes๐Ÿ“ Bethesda Praxis Precision Medicines ยท Tests: 30mg PRAX-628 A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome NCT04462770Phase 368 sites๐Ÿ“ Birmingham๐Ÿ“ Little Rock๐Ÿ“ Los Angeles Epygenix ยท Tests: Clemizole HCl, Placebo Multicentre Real-life Follow-up Study of Rare Epileptic Syndromes in Children and Adolescents NCT05126914n/a11 sites๐Ÿ“ Angers๐Ÿ“ Bordeaux๐Ÿ“ Brest Assistance Publique - Hรดpitaux de Paris Characterization by Automated System on Infantile Spasmes NCT06266234n/a1 site๐Ÿ“ Garches Assistance Publique - Hรดpitaux de Paris A Study to Evaluate the Safety and Pharmacokinetics of RC001 in Children With Dravet Syndrome NCT07675746EARLY Phase 11 site๐Ÿ“ Guangzhou Second Affiliated Hospital of Guangzhou Medical University ยท Tests: RC001 injection-Dose Escalation Cohort, RC001 injection-Fixed Dose Cohort Electroclinical Correlation of Anxiety NCT05393518NA1 site๐Ÿ“ Bordeaux University Hospital, Bordeaux ยท Tests: Anxiety-induced task, Neuropsychiatric assessment A PET-MRI Study of Serotoninergic Brainstem Pathway in Patients With Dravet Syndrome NCT07013331NA1 site๐Ÿ“ Bron Hospices Civils de Lyon ยท Tests: [18F]MPPF PET-MRI Study of Transcranial Direct Current Stimulation to Treat Epilepsy NCT05673915NA1 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: ActivaDose II 0.1 mA transcranial direct current stimulation (tDCS), ActivaDose II 2.0 mA transcranial direct current sโ€ฆ Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a2 sites๐Ÿ“ Sioux Falls๐Ÿ“ Sydney Sanford Health A Safety and Efficacy of Intrathecally Administered ION283 in Patients With Lafora Disease NCT06609889Phase 1, Phase 21 site๐Ÿ“ Dallas Berge Minassian ยท Tests: ION283 A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome NCT05419492Phase 1, Phase 214 sites๐Ÿ“ San Francisco๐Ÿ“ Aurora๐Ÿ“ Miami Encoded Therapeutics ยท Tests: ETX101 A Clinical Study on the Efficacy and Safety of Zonisamide as a First Add-On Treatment in Epileptic Seizures NCT06967012Phase 41 site๐Ÿ“ Nantong Affiliated Hospital of Nantong University ยท Tests: Oral Zonisamide Therapy Idiopathic Generalized Epilepsy Syndromes NCT06388174n/a1 site๐Ÿ“ Hangzhou Shen Chun-Hong Vigabatrin With High Dose Prednisolone Combination Therapy vs Vigabatrin Alone for Infantile Spasm NCT04302116NA1 site๐Ÿ“ Ratchathewi Kullasate Sakpichaisakul ยท Tests: Combination therapy with vigabatrin and prednisolone, Vigabatrin Tablets BMB-101 in Absence Epilepsy and DEE NCT06401538Phase 25 sites๐Ÿ“ Randwick๐Ÿ“ Herston๐Ÿ“ Fitzroy Bright Minds Biosciences Pty Ltd ยท Tests: BMB-101 North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC) NCT01694940n/a17 sites๐Ÿ“ San Diego๐Ÿ“ Stanford๐Ÿ“ Aurora Columbia University Exogenous Ketone Esters for Refractory Status Epileptics NCT05674552Phase 2, Phase 31 site๐Ÿ“ Sohag Sohag University ยท Tests: Exogenous ketone ester ONO-2017 Study Japanese Patients With Primary Generalized Tonic Clonic Seizures. NCT06579573Phase 325 sites๐Ÿ“ Aichi๐Ÿ“ Fukuoka๐Ÿ“ Fukushima Ono Pharmaceutical Co., Ltd. ยท Tests: Cenobamate Idiopathic Generalized Epilepsy Cognitive and Emotional Profile NCT06782074n/a1 site๐Ÿ“ Pavia IRCCS National Neurological Institute "C. Mondino" Foundatiโ€ฆ ยท Tests: emotional and neuropsychological assessment Etiology and Treatment of Neonatal Seizure NCT03822741n/a1 site๐Ÿ“ Shanghai Children's Hospital of Fudan University Assessment of Safety of the Use of Fenfluramine in Children With Dravet Syndrome Under 24 Months of Age NCT06598449Phase 41 site๐Ÿ“ Aurora University of Colorado, Denver ยท Tests: fenfluramine Baker Gordon Syndrome Natural History Study NCT06399952n/a1 site๐Ÿ“ Columbia University of Missouri-Columbia ยท Tests: Brain Magnetic Resonance Imaging (MRI), Whole Genome Sequencing, Induced Pluripotential Stem Cells Epilepsy Learning Healthcare System (ELHS) NCT06265103n/a13 sites๐Ÿ“ Phoenix๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Epilepsy Foundation of America ยท Tests: Clinical care and quality improvement A Study to Prevent Infantile Spasms Relapse NCT06819670Phase 21 site๐Ÿ“ Los Angeles University of California, Los Angeles ยท Tests: Prednisolone, Famotidine, Placebo
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