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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Germ Cell Cancer Metastatic

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma NCT06581406Phase 2, Phase 333 sites📍 Scottsdale📍 La Jolla📍 Los Angeles Replimune, Inc. · Tests: RP2, Ipilimumab, Nivolumab Immunotherapy Efficacy and PD-L1 as a Predictive Biomarker in Metastatic Melanoma in Slovenia NCT07422779NA1 site📍 Ljubljana Institute of Oncology Ljubljana · Tests: Pembrolizumab, Nivolumab, Ipilimumab TIL Therapy in cSCC and MCC NCT07288073Phase 21 site📍 Boston Karam Khaddour, MD, MS · Tests: LN-145, Cyclophosphamide, Fludarabine, Interleukin-2 Dual-Target CSPG4/GD2 CAR-NK Cells for Advanced Melanoma NCT07627698Phase 1, Phase 21 site📍 Shenzhen Beijing Biotech · Tests: EB-DTKN-401 allogeneic dual-target CSPG4/GD2 CAR-NK cells, Fludarabine, Cyclophosphamide Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions NCT04047264NA1 site📍 Rochester Mayo Clinic · Tests: Microdialysis, Magnetic Resonance Imaging, Computed Tomography A Study of Armored CAR T Cells in People With Cancer NCT07783477Phase 17 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: DLL3-SAVVYZ-IL18 CAR T cell Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours NCT02582697Phase 356 sites📍 Downey📍 Loma Linda📍 Long Beach University of Sydney · Tests: Bleomycin (active name: Bleomycin Sulfate), Etoposide, Cisplatin, Pegylated G-CSF (Pegfilgrastim), Filgrastim Safety and Efficacy of OBX-115 in Advanced Solid Tumors NCT06060613Phase 1, Phase 210 sites📍 Los Angeles📍 Los Angeles📍 Stanford Obsidian Therapeutics, Inc. · Tests: OBX-115 Evaluation of the CONVIVO System NCT05139277NA1 site📍 Lebanon Dartmouth-Hitchcock Medical Center · Tests: CONVIVO system, Conventional histologic evaluation Detection of the BRAF V600E Mutation in Liquid Biopsy Using the CRISPR/Cas12a System NCT07870265NA1 site📍 Brno Masaryk Memorial Cancer Institute · Tests: Novel CRISPR/Cas12a Electrochemical Bioassay, Reference Standard Molecular Diagnostics (NGS and ddPCR), Serial Peripher… Evaluation of the Safety, Efficacy, and Pharmacokinetics of NBM-BMX in Patients With Metastatic Uveal Melanoma NCT07136181Phase 1, Phase 23 sites📍 Scottsdale📍 Denver📍 Nashville Novelwise Pharmaceutical Corporation · Tests: NBM-BMX Capsule are proprietary products developed by Novelwise Pharmaceutical Corporation (Novelwise) for treatment of… To Evaluate the Safety and Efficacy of ADP-TILIL7 in Patients With Locally Advanced or Metastatic Melanoma NCT06204991Phase 12 sites📍 Herlev📍 Herlev Inge Marie Svane · Tests: ADP-TILIL7, Cyclophosphamide, Fludarabine Phosphate, Proleukin Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study NCT07405086Phase 41 site📍 Portland OHSU Knight Cancer Institute · Tests: Biospecimen Collection, Immune Checkpoint Inhibitor Anti PD-1 Plus Postbiotic Versus Anti PD-1 Alone in Locally Advanced or Metastatic, Treatment naïve, Cutaneous Melanoma Study NCT07050940NA5 sites📍 Bari📍 Torino📍 Bari Azienda Ospedaliera di Perugia · Tests: Postbiotic, AntiPD1 A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5) NCT07492680Phase 258 sites📍 San Francisco📍 Aurora📍 Atlanta Bristol-Myers Squibb · Tests: BMS-986504, Daraxonrasib, Nivolumab + Relatlimab FDC, Temozolomide, Pumitamig Pilot IntraOperative Neuronal Electrophysiology in Tumor rElatEd suRgery NCT06617208NA1 site📍 Rotterdam Erasmus Medical Center · Tests: Neuropixel probe recording Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors NCT04771520Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Avapritinib A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas. NCT06022029Phase 116 sites📍 Los Angeles📍 Tamarac📍 Canton OncoNano Medicine, Inc. · Tests: ONM-501, Cemiplimab A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, Dedifferentiated Liposarcoma, or Angiosarcoma NCT05607095Phase 12 sites📍 Harrison📍 New York Memorial Sloan Kettering Cancer Center · Tests: Lifileucel (LN-144/LN-145) Advanced Diffusion MRI to Differentiate Tumor Recurrence From Pseudoprogression in Patients With Glioblastoma and Brain Metastases NCT05911230NA1 site📍 Basel University Hospital, Basel, Switzerland · Tests: Advanced diffusion-weighted MRI (ADW-MRI) Dabrafenib and/or Trametinib Rollover Study NCT03340506Phase 438 sites📍 Scottsdale📍 Bethesda📍 Columbus Novartis Pharmaceuticals · Tests: dabrafenib, trametinib 177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors NCT06305962EARLY Phase 15 sites📍 Kingswood📍 Wollongong📍 Southport Radiopharm Theranostics, Ltd · Tests: 177Lu-RAD204 A Ketogenic Diet as a Complementary Treatment on Patients With High-grade Gliomas and Brain Metastases NCT05564949NA2 sites📍 Chaïdári📍 Athens Attikon Hospital · Tests: CKD RP1 in Primary Melanoma to Reduce the Risk of Sentinel Lymph Node Metastasis NCT06216938EARLY Phase 11 site📍 Pittsburgh Yana Najjar · Tests: Vusolimogene oderparepvec (RP1) A Phase 0/1 Clinical Trial With an Expansion Phase of GSK5764227, a B7-H3-Targeted Antibody-Drug Conjugate (ADC), in Patients With Recurrent Grade 4 Glioma and Patients With Brain Metastases NCT07268053EARLY Phase 11 site📍 Phoenix Nader Sanai · Tests: Risvutatug rezetecan Dose-defining Study of Tirapazamine Combined With Embolization in Liver Cancer NCT02174549Phase 1, Phase 22 sites📍 Palo Alto📍 Philadelphia Teclison Ltd. · Tests: Tirapazamine, Conventional Transarterial Embolization (TAE) IDOV-Immune for Advanced Solid Tumors NCT06910657Phase 15 sites📍 St Louis📍 Houston📍 San Antonio ViroMissile, Inc. · Tests: IDOV-Immune (oncolytic vaccinia virus) Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers NCT05296564Phase 1, Phase 21 site📍 Jerusalem Hadassah Medical Organization · Tests: CYCLOPHOSPHAMIDE and FLUDARABIN, Cyclophosphamide, HBI 0201-ESO TCRT, Aldesleukin A Phase 1 Study of TGI-5 as Monotherapy and in Combination With Nivolumab in Subjects With Locally Advanced/Metastatic Solid Tumors NCT07376707Phase 11 site📍 Shanghai Hefei TG ImmunoPharma Co., Ltd. · Tests: TGI-5 Immune Response to Percutaneous Hepatic Perfusion With Melphalan for Ocular Melanoma Metastatic to the Liver NCT07364474NA1 site📍 Boston Massachusetts General Hospital · Tests: Melphalan through Percutaneous Hepatic Perfusion, Melphalan through Percutaneous Hepatic Perfusion in combination with …
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