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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Glioblastoma Multiforme of Brain

Sonodynamic Therapy in Patients With Recurrent GBM NCT06039709Phase 11 site📍 Charlottesville Shayan Moosa, MD · Tests: 5-ALA and Low-Intensity Focused Ultrasound (SDT) A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 Gliomas NCT07003542Phase 21 site📍 Cleveland Case Comprehensive Cancer Center · Tests: Sitagliptin Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions NCT04047264NA1 site📍 Rochester Mayo Clinic · Tests: Microdialysis, Magnetic Resonance Imaging, Computed Tomography Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA NCT01269853Phase 1, Phase 21 site📍 New York Northwell Health · Tests: Bevacizumab, Bevacizumab Application of FET-PET in Fusion With MRI in the Treatment of Glioblastoma Multiforme [TYR-GLIO] NCT06466031NA1 site📍 Lodz Copernicus Memorial Hospital · Tests: MRI & PET fusion, MRI+T1C Injection of Active Allogeneic Natural Killer Cells in Patients With Gliomas NCT06687681Phase 21 site📍 Tehran Marzieh Ebrahimi · Tests: NK cell therapy Evaluation of the CONVIVO System NCT05139277NA1 site📍 Lebanon Dartmouth-Hitchcock Medical Center · Tests: CONVIVO system, Conventional histologic evaluation Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma NCT06991101Phase 22 sites📍 Miami📍 New York Baptist Health South Florida · Tests: Ruxolitinib, Temozolomide, Radiation Therapy Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII NCT07326566Phase 235 sites📍 Birmingham📍 Springdale📍 La Jolla Black Diamond Therapeutics, Inc. · Tests: silevertinib in combination with temozolomide, temozolomide (TMZ) Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy NCT07179328Phase 11 site📍 Toronto Sunnybrook Health Sciences Centre · Tests: Focused Ultrasound Next Generation Dome Helmet, Definity® Vial for (Perflutren Lipid Microsphere) Injectable Suspension Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) NCT04427384n/a54 sites📍 Phoenix📍 Little Rock📍 Castro Valley GT Medical Technologies, Inc. · Tests: GammaTile Key Longitudinal Associations With Risk and Glioblastoma Outcomes NCT06625684n/a1 site📍 Durham Duke University A Phase 0/1 Clinical Trial With an Expansion Phase of GSK5764227, a B7-H3-Targeted Antibody-Drug Conjugate (ADC), in Patients With Recurrent Grade 4 Glioma and Patients With Brain Metastases NCT07268053EARLY Phase 11 site📍 Phoenix Nader Sanai · Tests: Risvutatug rezetecan Impact of Salovum® and SPC® Flakes on Brain Tumor Induced Edema NCT06710249Phase 21 site📍 Lund Peter Siesjö · Tests: Salovum/SPC flakes GPC-3 CAR T CELLS FOR Recurrent GPC-3 Positive Glioblastoma NCT06815432Phase 11 site📍 Houston Baylor College of Medicine · Tests: 15.GPC3-CAR T cells Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases NCT05909618Phase 21 site📍 Ramat Gan Sheba Medical Center · Tests: Crizanlizumab-Tmca 10 MG/1 ML Intravenous Solution [ADAKVEO], Nivolumab 10 MG/1 ML Intravenous Solution [OPDIVO] Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188Phase 1, Phase 21 site📍 Bethesda National Institute of Neurological Disorders and Stroke (NI… · Tests: LMP744, Conventional Surgery or Biopsy Study of Low-Intensity Focused Ultrasound in Combination With Immunotherapy in Newly Diagnosed Unmethylated Glioblastoma NCT07343986Phase 11 site📍 Charlottesville University of Virginia · Tests: anti-EGFR bispecific-armed T cells, Low-Intensity Focused Ultrasound A Clinical Trial Testing the Safety of the Investigational Drug Pumitamig (BNT327) and How Well it Works in Patients With Recurrent Glioblastoma NCT07297212Phase 26 sites📍 Beijing📍 Chongqing📍 Jinan BioNTech SE · Tests: Pumitamig, Bevacizumab, Temozolomide A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma NCT06552260EARLY Phase 13 sites📍 Boston📍 Boston📍 Boston Ugonma Chukwueke · Tests: Troriluzole A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites📍 Washington D.C.📍 Gainesville University of Florida · Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP li… Characterization of the Blood-Brain Barrier in High-Grade Glioma Through Immunohistochemical, Transcriptional, Fluorescein and Radiological Analyses NCT07731555NA1 site📍 Beaumont Patrick Morris · Tests: Multimodal Blood Brain Barrier Assessment 5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours NCT06630260Phase 1, Phase 23 sites📍 Cambridge📍 Sutton📍 Sutton Institute of Cancer Research, United Kingdom · Tests: Avutometinib, Defactinib, Temozolomide Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion NCT05990244NA1 site📍 Shenyang Shengjing Hospital · Tests: Magnetic Resonance Elastography, Assessment and Recording Glutamate Inhibitors in Glioblastoma NCT05664464Phase 1, Phase 21 site📍 Zurich University of Zurich · Tests: Gabapentin, Sulfasalazine, Memantine, Temozolomide, Radiotherapy Feasibility of FMISO in Brain Tumors NCT03649880Phase 21 site📍 Portland OHSU Knight Cancer Institute · Tests: ¹⁸F-Fluoromisonidazole, Computed Tomography, Magnetic Resonance Imaging, Positron Emission Tomography, Oxygen Therapy Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment NCT05432804Phase 1, Phase 239 sites📍 Phoenix📍 Duarte📍 Irvine National Cancer Institute (NCI) · Tests: Biospecimen Collection, Magnetic Resonance Imaging, Placebo Administration, Selinexor, Temozolomide A Rollover Study of NBM-BMX in Combination With Temozolomide in Patients With Newly Diagnosed Glioblastoma NCT07569042Phase 1, Phase 23 sites📍 Kaohsiung City📍 Taichung📍 Taoyuan City Novelwise Pharmaceutical Corporation · Tests: NBM-BMX Capsule, Temozolomide HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors NCT03911388Phase 13 sites📍 Birmingham📍 St Louis📍 Houston M.D. Anderson Cancer Center · Tests: G207 B7-H3 Chimeric Antigen Receptor T Cells (B7-H3CART) in Recurrent Glioblastoma Multiforme NCT05474378Phase 11 site📍 Palo Alto Stanford University · Tests: B7-H3CART
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