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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Hereditary Malignant Neoplasm

Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST) NCT06222203n/a1 site📍 Bethesda National Cancer Institute (NCI) Oral Hedgehog Inhibitors in the Treatment of Basal Cell Carcinoma in the Netherlands: a Prospective Registration Study NCT05463757n/a8 sites📍 Nijmegen📍 Maastricht📍 Amsterdam Maastricht University Medical Center · Tests: Vismodegib, Sonidegib Trial of Combined Obstetric Carrier Screening and Hereditary Cancer Screening NCT07052266NA5 sites📍 Brooklyn📍 Brooklyn📍 New York Weill Medical College of Cornell University · Tests: MyRisk Hereditary Cancer Test A Phase 1b/2 Study of the Safety and Efficacy of the Monoclonal Antibody OM-RCA-01 in Patients With Metastatic Tumors Expressing Fibroblast Growth Factor Receptor 1 NCT07292168Phase 1, Phase 25 sites📍 Kazan'📍 Krasnoyarsk📍 Moscow Kidney Cancer Research Bureau · Tests: humanized monoclonal anti-FGFR1 antibody OM-RCA-01 Implementation of eHealth Delivery Alternatives for Cancer Genetic Testing for Hereditary Cancer (eREACH3) NCT07471958n/a1 site📍 Philadelphia Abramson Cancer Center at Penn Medicine Increasing Germline Genetic Testing for Patients With Cancer NCT07307664NA10 sites📍 Los Angeles📍 Orlando📍 Decatur Josh Peterson · Tests: Implementation strategies Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1 Using Novel Magnetic Resonance Imaging Techniques Paired With Artificial Intelligence NCT04763109NA1 site📍 Los Angeles Nicole Baca · Tests: Whole-body Magnetic Resonance Imaging Integration of the PD-L1 Inhibitor Atezolizumab and WT1/DC Vaccination Into Platinum/Pemetrexed-based First-line Treatment for Epithelioid Malignant Pleural Mesothelioma NCT05765084Phase 1, Phase 23 sites📍 Edegem📍 Ghent📍 Sint-Niklaas University Hospital, Antwerp · Tests: Dendritic cell vaccination, Atezolizumab, Platinum/pemetrexed based chemotherapy MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies NCT05735717Phase 21 site📍 Minneapolis Masonic Cancer Center, University of Minnesota · Tests: Fludarabine, Busulfan, Melphalan, Rituximab, Levetiracetam An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors NCT07371663Phase 1, Phase 23 sites📍 Beijing📍 Zhengzhou📍 Hangzhou Beijing Tide Pharmaceutical Co., Ltd · Tests: TCC1727 tablet 90mg, TCC1727 tablet 120mg, TCC1727 tablet 160mg, benmelstobart Injection TSC Biosample Repository and Natural History Database NCT05676099n/a26 sites📍 Birmingham📍 Loma Linda📍 Los Angeles National Tuberous Sclerosis Association · Tests: Phlebotomy, Buccal (cheek) swab, Genetic Testing, Tissue donation after routine clinical procedure Implementation of Population Cancer Genetic Services in Federally Qualified Health Centers (FQHC) NCT05664867NA1 site📍 Chicago University of Illinois at Chicago · Tests: Mainstream Genetic Testing Model, Enhanced Standard of Care Model Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells NCT07148050Phase 11 site📍 Seattle Seattle Children's Hospital · Tests: SC-CAR.GPC3xIL15.21 CAR T cells Lynch Syndrome X-Talk of Enteral Mucosa With Immune System NCT06708429n/a5 sites📍 Monrovia📍 Milan📍 Milan San Raffaele University · Tests: LYNX EYE (Lynch syndrome X-Talk of Enteral mucosa with Immune System) EXOME Analysis Position in the Strategy of Genetic Predisposition Factors Identification in Early-onset Cancer NCT04141462NA6 sites📍 Besançon📍 Dijon📍 Dijon Centre Georges Francois Leclerc · Tests: blood sample EHR Intervention to Increase HBOC Genetic Testing NCT07876349NA1 site📍 New York Columbia University · Tests: ELISABETH Evidence-Informed Program (EIP) Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors NCT07584499Phase 11 site📍 Guangzhou Sun Yat-sen University · Tests: Becotatug Vedotin Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders NCT04644016Phase 21 site📍 New York Memorial Sloan Kettering Cancer Center · Tests: Clofarabine, Fludarabine, Busulfan, Cyclosporine-A, Mycophenolate Mofetil A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors NCT04657068Phase 1, Phase 288 sites📍 Birmingham📍 Scottsdale📍 Little Rock Artios Pharma Ltd · Tests: ART0380, Gemcitabine, Irinotecan Natural History of Familial Carcinoid Tumor NCT00646022n/a1 site📍 Bethesda National Institute of Diabetes and Digestive and Kidney Dis… · Tests: [18F]-DOPA Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics NCT05694559NA1 site📍 Houston M.D. Anderson Cancer Center · Tests: Genetic Testing and Counseling, Screening Form NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) NCT06239272Phase 1, Phase 27 sites📍 Atlanta📍 Chicago📍 Baton Rouge St. Jude Children's Research Hospital · Tests: Surgical resection, Proton beam radiation therapy, Pazopanib, Ifosfamide, Doxorubicin Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST NCT06735820Phase 1, Phase 22 sites📍 Washington D.C.📍 Dallas AeRang Kim · Tests: APG-115, Selumetinib B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR) NCT04897321Phase 11 site📍 Memphis St. Jude Children's Research Hospital · Tests: Fludarabine, Cyclophosphamide, MESNA, B7-H3 CAR T cells InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer NCT05463796n/a1 site📍 Boston Dana-Farber Cancer Institute · Tests: Samples Navigation Interventions to Improve Cascade Genetic Testing Among Relatives of Patients With Hereditary Cancer Syndromes NCT06927947NA1 site📍 Ann Arbor University of Michigan Rogel Cancer Center · Tests: Communication Intervention, Health Promotion and Education, Informational Intervention, Survey Administration Integrated Cancer Repository for Cancer Research NCT02012699n/a42 sites📍 Greenwood Village📍 Manchester📍 Daytona Beach University of Nebraska Familial Investigations of Childhood Cancer Predisposition NCT03050268n/a1 site📍 Memphis St. Jude Children's Research Hospital FOG-001 in Locally Advanced or Metastatic Solid Tumors NCT05919264Phase 1, Phase 233 sites📍 Phoenix📍 Scottsdale📍 Tucson Parabilis Medicines, Inc. · Tests: FOG-001, mFOLFOX-6, Nivolumab, Trifluridine/tipiracil, Bevacizumab CfDNA in Hereditary And High-risk Malignancies 2 NCT06726642n/a8 sites📍 Vancouver📍 St. John's📍 Halifax University Health Network, Toronto · Tests: Cell-free DNA analysis
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