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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for High Risk Prostate Cancer

ABlative Radiotherapy (for) Unfavorable Prostate Tumors NCT04831983n/a1 site๐Ÿ“ Monza University of Milano Bicocca Safety and Early Efficacy of Radical Prostatectomy for Newly Diagnosed Very High Risk Locally Advanced and Oligometastatic Prostate Cancer NCT02971358NA1 site๐Ÿ“ Vienna Medical University of Vienna ยท Tests: Radical prostatectomy PRO-BOOST-LC: Whole-Gland Boost Strategies Versus SBRT Monotherapy in PSMA-Staged Localized and Locally Advanced Prostate Cancer NCT07426055Phase 2, Phase 31 site๐Ÿ“ Zamoล›ฤ‡ Affidea Nu-med Center of Oncological DIagnostics and Therapy ยท Tests: Stereotactic Body Radiotherapy (SBRT) Monotherapy, External Beam Radiotherapy (EBRT) Backbone, High-Dose-Rate Brachytheโ€ฆ Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort NCT05384535NA1 site๐Ÿ“ Lake Success Northwell Health ยท Tests: Bi-parametric MRI High Dose Rate (HDR) Brachytherapy Salvage After Prostatectomy NCT06982469n/a1 site๐Ÿ“ Pamplona Clinica Universidad de Navarra, Universidad de Navarra ยท Tests: Brachytherapy Implementation of Precision Medicine in High-risk Prostate Cancer NCT06687421n/a1 site๐Ÿ“ Umeรฅ Andreas Josefsson ยท Tests: High-risk treatment SOC, Active monitoring, Radical prostatectomy, Radiotherapy, Androgen deprivation therapy Efficacy and Safety of Radical Prostatectomy (RP) With or Without Salvage Radiotherapy Versus RP With Extended Pelvic Lymph Node Dissection for Localized Intermediate- and High-risk Prostate Cancer With a Briganti Nomogramโ‰ฅ7% NCT07115992NA1 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: RARPยฑSRT, RARP+ePLND High Dose-Rate Brachytherapy and Stereotactic Body Radiotherapy for the Treatment of Prostate Adenocarcinoma NCT04945642NA1 site๐Ÿ“ Los Angeles Jonsson Comprehensive Cancer Center ยท Tests: High-Dose Rate Brachytherapy, Stereotactic Body Radiation Therapy Image-guided, Tumor-focused Radiotherapy Treatment in Intermediate and High-risk Prostate Cancer NCT06990542Phase 21 site๐Ÿ“ La Jolla University of California, San Diego ยท Tests: Image-guided tumor-focused radiation therapy Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial NCT06499870Phase 21 site๐Ÿ“ Chicago Sean Sachdev ยท Tests: Biopsy, Biospecimen Collection, Computed Tomography, Enzalutamide, Fluorine F 18 Piflufolastat FK-PC101 as Adjuvant Therapy for Men With High-Risk Prostate Cancer NCT06636682Phase 23 sites๐Ÿ“ Chicago๐Ÿ“ Gahanna๐Ÿ“ Myrtle Beach Cellvax Therapeutics Inc ยท Tests: FK-PC101, Standard of Care (SOC) Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients Utilizing 18F-Flotufolastat PSMA PET/CT NCT07455903Phase 21 site๐Ÿ“ Miami Baptist Health South Florida ยท Tests: Leuprolide, Degarelix, Relugolix, Triptorelin, Bicalutamide Treatment of High-Risk Prostate Cancer Guided by Novel Diagnostic Radio- and Molecular Tracers NCT06282588Phase 2, Phase 39 sites๐Ÿ“ Wilrijk๐Ÿ“ Aalst๐Ÿ“ Bruges Cancer Research Antwerp ยท Tests: Darolutamide, Darolutamide matched placebo, Radiotherapy, Zoladex 3.6Mg Implant, Zoladex LA High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers NCT05011383Phase 217 sites๐Ÿ“ Aurora๐Ÿ“ West Haven๐Ÿ“ Gainesville VA Office of Research and Development ยท Tests: High dose testosterone Detection of Minimal Residual Disease Post-prostatectomy NCT07334275n/a1 site๐Ÿ“ Nijmegen Radboud University Medical Center Dose Optimization and Diagnostic Performance in Prostate Cancer (SPARROW [Staging Prostate Cancer With Advanced RM2 Radiotracer Oncologic Workup]) NCT07831824Phase 2, Phase 31 site๐Ÿ“ Grand Rapids Lantheus Medical Imaging ยท Tests: [68Ga]-LNTH-2401 Focal Therapy for Localized Prostate Cancer NCT06270043n/a1 site๐Ÿ“ La Jolla University of California, San Diego ยท Tests: Focal Therapy Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy NCT06056830Phase 334 sites๐Ÿ“ Birmingham๐Ÿ“ Phoenix๐Ÿ“ Little Rock Clarity Pharmaceuticals Ltd ยท Tests: 64Cu-SAR-bisPSMA Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer NCT06613100Phase 19 sites๐Ÿ“ San Francisco๐Ÿ“ St Louis๐Ÿ“ Columbus Amgen ยท Tests: Xaluritamig, GnRH Antagonist Adaptive Radiation Therapy for Men With Intermediate- or High-Risk Prostate Cancer NCT07219303NA1 site๐Ÿ“ Philadelphia Fox Chase Cancer Center ยท Tests: adaptive stereotactic body radiation therapy (SBRT) with a SIB Safety of Dose Escalation in Definitive Hypofractionated Radiation Therapy and Hormone Therapy With SpaceOAR TM for Patients With High - Risk Localized Prostate Cancer (DESAR-H) NCT06461793Phase 21 site๐Ÿ“ Seoul Samsung Medical Center ยท Tests: Dose increase after injection of biodegradable material A safety study of high-risk prostate cancer patients Salvage HDR for Locally Recurrent Prostate Cancer NCT04231006NA1 site๐Ÿ“ Aarhus Aarhus University Hospital ยท Tests: High dose rate brachytherapy Bipolar Androgen Therapy + Carboplatin in mCRPC NCT03522064Phase 21 site๐Ÿ“ Sydney St Vincent's Hospital, Sydney ยท Tests: Testosterone Enanthate 100 MG/ML Injectable Solution, Testosterone Enanthate 100 MG/ML Injectable Solution / Carboplatiโ€ฆ Neoadjuvant Therapy of Darolutamide Plus ADT for High Risk Prostate Cancer NCT06575257Phase 21 site๐Ÿ“ Xiโ€™an Xijing Hospital ยท Tests: Darolutamide, Goserelin 3.6 mg Circulating Tumor DNA in High Risk Localized Prostate Cancer NCT07222436n/a1 site๐Ÿ“ Pittsburgh University of Pittsburgh A Platform Study of Epigenetic Therapy Before Prostatectomy in Men With Prostate Cancer NCT06888102EARLY Phase 11 site๐Ÿ“ Los Angeles Edwin Posadas, MD ยท Tests: Neoadjuvant Epigenetic Therapy Neoadjuvant ADT + Darolutamide With Pembrolizumab, Followed by Adjuvant Pembrolizumab in Molecularly Stratified High-Risk Prostate Cancer NCT07027124Phase 21 site๐Ÿ“ New York Icahn School of Medicine at Mount Sinai ยท Tests: Darolutamide, Pembrolizumab, Lupron Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation NCT05806515Phase 2133 sites๐Ÿ“ Anchorage๐Ÿ“ Anchorage๐Ÿ“ Anchorage SWOG Cancer Research Network ยท Tests: Biospecimen Collection, Carboplatin, Chest Radiography, Computed Tomography, Magnetic Resonance Imaging SbrtยฑsTad for Unfavorable iNtermediate rIsk/High Risk Prostate caNcer NCT05557604Phase 23 sites๐Ÿ“ Rome๐Ÿ“ Rome๐Ÿ“ Rome Regina Elena Cancer Institute ยท Tests: Decapeptyl Identify Genes/Pathways Responsible for Progression From Low Risk to Higher Risk Prostate Cancer NCT03789253n/a1 site๐Ÿ“ Taipei National Taiwan University Hospital
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