🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

🧪

Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

30 recruiting trials

for Langerhans Cell Histiocytosis

Adult Pulmonary Langerhans Cell Histiocytosis: a National Registry-based Prospective Cohort Study NCT04665674n/a1 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: Standard of care Q702 for the Treatment of Patients With Hematologic Malignancies NCT06712810Phase 12 sites📍 Scottsdale📍 Rochester Mayo Clinic · Tests: Axl/Mer/CSF1R Inhibitor Q702, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography Retinal Hyperspectral Imaging in Neurodegenerative Diseases NCT07545473NA1 site📍 Melbourne Center for Eye Research Australia · Tests: Hyperspectral camera Luvometinib in Pediatric SS-LCH With Special-site Single/Multifocal Bone Lesions NCT07371182NA11 sites📍 Hefei📍 Nanning📍 Guiyang West China Second University Hospital · Tests: Luvometinib A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC) NCT07082725Phase 334 sites📍 Oakland📍 Minneapolis📍 Rochester Azafaros B.V. · Tests: Nizubaglustat, Placebo Efficacy and Safety of Low-Dose Cytarabine Combined With Thalidomide in Adult Patients With Untreated LCH NCT07187193Phase 21 site📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: Cytarabine (Ara-C), Thalidomide (100mg) Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC NCT04528355n/a1 site📍 Pittsburgh Paul Szabolcs · Tests: data collection Real-world Study of Darafenib or Trametinib and Clofarabine for High-risk/Recurrent/Refractory Langerhans Cell Histiocytosis in Children NCT07022834Phase 21 site📍 Chengdu West China Second University Hospital · Tests: Dabrafenib or Trametinib and Clofarabine Registry for Patients With Erdheim-Chester Disease and Other Histiocytoses NCT03329274n/a1 site📍 New York Memorial Sloan Kettering Cancer Center GammaGA: Prevalence of Acid Sphingomyelinase Deficiency Disease (ASMD) and Gaucher Disease in Patients With Monoclonal Gammopathies and/or Multiple Myeloma NCT05992532n/a23 sites📍 Vitoria-Gasteiz📍 Almería📍 Palma de Mallorca Fundación Española de Hematología y Hemoterapía A Pivotal Study of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C NCT05163288Phase 314 sites📍 Rochester📍 Parkville📍 Prague IntraBio Inc · Tests: N-Acetyl-L-Leucine, Placebo National Multicentre Study of the Natural History of Acid Sphingo-myelinase Deficiency in Adults and Children NCT06985212n/a1 site📍 Paris Wladimir MAUHIN, Dr Oral Prednisone in Treating LCH of Bone in Childhood and Adolescence NCT06078969Phase 21 site📍 Shanghai Shanghai Changzheng Hospital · Tests: Prednisone Mirdametinib in Histiocytic Disorders NCT06153173Phase 21 site📍 Cincinnati Children's Hospital Medical Center, Cincinnati · Tests: Mirdametinib UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells NCT02254863Phase 11 site📍 Durham Joanne Kurtzberg, MD · Tests: DUOC-01 Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a2 sites📍 Sioux Falls📍 Sydney Sanford Health A Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD) NCT06192576n/a6 sites📍 Chicago📍 Cincinnati📍 Columbus Sanofi · Tests: Olipudase alfa Project: Every Child for Younger Patients With Cancer NCT02402244n/a279 sites📍 Birmingham📍 Mobile📍 Anchorage Children's Oncology Group · Tests: Cytology Specimen Collection Procedure, Medical Chart Review Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type C NCT00344331n/a1 site📍 Bethesda Eunice Kennedy Shriver National Institute of Child Health a… CytOSorb TreatMent Of Critically Ill PatientS Registry NCT05146336n/a28 sites📍 Klagenfurt📍 Vienna📍 Aachen CytoSorbents, Inc · Tests: CytoSorb Ruxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH) NCT06160791Phase 24 sites📍 Irvine📍 Sacramento📍 San Diego Jerry Lee, MD, MSc, MPhil · Tests: Ruxolitinib, Etoposide, Dexamethasone, Non-interventional Imaging, Research Biopsy Assessing the Presence of CT-DNA in Lymphoma Associated HLH NCT05702502n/a1 site📍 Nottingham Nottingham University Hospitals NHS Trust INTO-HLH: A Disease Registry for Patients With Hemophagocytic Lymphohistiocytosis (HLH) NCT05277272n/a1 site📍 Cincinnati Children's Hospital Medical Center, Cincinnati DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers. NCT05768178Phase 2, Phase 316 sites📍 Belfast📍 Birmingham📍 Bristol Cancer Research UK · Tests: Vemurafenib, Cobimetinib Prospective Cohort for Adult Hemophagocytosis NCT03117010n/a1 site📍 Seoul Samsung Medical Center · Tests: Steroids, Etoposide Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders NCT04079179Phase 212 sites📍 Phoenix📍 Little Rock📍 Orange Carl Allen · Tests: Cobimetinib Establishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type C NCT05588167n/a1 site📍 Bethesda Eunice Kennedy Shriver National Institute of Child Health a… DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers. NCT07440290Phase 2, Phase 327 sites📍 Belfast📍 Birmingham📍 Birmingham Cancer Research UK · Tests: Dabrafenib, Trametinib A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis NCT05828069Phase 2121 sites📍 Birmingham📍 Little Rock📍 Downey National Cancer Institute (NCI) · Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Echocardiography Test ECD-Score: a Study on Erdheim-Chester Disease NCT07454343n/a7 sites📍 Bethesda📍 Rochester📍 New York Meyer Children's Hospital IRCCS
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy