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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Low Rectal Cancer

Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery NCT03051464Phase 2, Phase 34 sites📍 Dallas📍 Montreal📍 Montreal Sir Mortimer B. Davis - Jewish General Hospital · Tests: Complete responders and Non-complete responders, Chemoradiation + EBRT Boost, Chemoradiation + HDRBT Boost Neoadjuvant Chemoradiotherapy Plus Tislelizumab With or Without Probio-M9 in pMMR/MSS Locally Advanced Rectal Cancer NCT07458529Phase 21 site📍 Beijing Seventh Medical Center of PLA General Hospital · Tests: CRT+PD-1 inhibitor+Probio-M9, CRT+PD-1 inhibitor+placebo Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer. NCT06758830Phase 2, Phase 31 site📍 Vilnius National Cancer Center Affiliate of Vilnius University Hosp… · Tests: Radiation Therapy, Chemoradiotherapy, Consolidation Chemotherapy, Surgery, Part two Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection NCT05939687Phase 31 site📍 Moscow Blokhin's Russian Cancer Research Center · Tests: mesh, non-mesh Nodes-sparing Short-course Radiation Combined With CAPOX and Tislelizumab for MSS Middle and Low Rectal Cancer NCT05972655Phase 21 site📍 Hanzhou Sir Run Run Shaw Hospital · Tests: Modified short-course radiotherapy, PD-1 antibody, Capecitabine, Oxaliplatin Transanal Total Mesorectal Excision vs Robotic Total Mesorectal Excision NCT07651553NA1 site📍 Guangzhou Sun Yat-sen University · Tests: robotic surgery vs transanal total mesorectal excsion Standard Dose Versus High Dose of Radiotherapy in Rectal Preservation With Chemo-radiotherapy in Rectal Cancer Patients NCT04095299Phase 35 sites📍 Aalborg📍 Copenhagen📍 Næstved Vejle Hospital · Tests: 50.4 Gy to the tumor and elective volume, 62 Gy to the clinical tumor volume and 50.4 Gy to the elective volume, Capeci… Low Rectal Cancer Treated With Total Neoadjuvant Therapy Plus Concurrent Tislelizumab Immunotherapy NCT07561060Phase 1, Phase 21 site📍 Shanghai Fudan University · Tests: Tislelizumab, Capecitabine, Oxaliplatin, Capecitabine Randomized Controlled Study of Plasma ctDNA Methylation-Guided Adjuvant Chemotherapy in Stage I/Low-Risk Stage II Colorectal Cancer NCT07562659Phase 21 site📍 Shanghai Fudan University · Tests: Capecitabine The Ohio State University (OSU) SCREEN Community Program NCT06666192NA1 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: Cancer Screening, Discussion, Educational Activity, Educational Intervention, Focus Group Safety of Mid and Low Rectal Cancer Surgery Without Dissection of the No.253 Lymph Node (S-M-O-O-T-H) NCT06146946NA8 sites📍 Beijing📍 Beijing📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: Dissection of the No.253 lymph node, Omitting the dissection of the No.253 lymph node Choice of the Optimal Treatment Strategies for Mid-low REctal Cancer NCT05871762n/a1 site📍 Beijing Peking Union Medical College Hospital · Tests: Registry study, no specific intervention REsults of LOw Anterior Resections With or Without Preventive Stoma in Nonemergency Department NCT07463261NA7 sites📍 Moscow📍 Moscow📍 Moscow ANO Scientific and Practical Club for the Development of Mo… · Tests: Without a preventive stoma, With a preventive stoma Understanding and Tailored Treatment of Low Anterior Resection Syndrome NCT07573371n/a3 sites📍 Aalborg📍 Aarhus📍 Vejle Aalborg University Hospital A Single-arm Phase II Clinical Study of Camrelizumab Combined With Long-course Chemoradiotherapy for Total Neoadjuvant Therapy in Locally Advanced Low pMMR/MSS Rectal Cancer NCT07527026Phase 21 site📍 Beijing Chinese PLA General Hospital · Tests: Camrelizumab Exosomes in Rectal Cancer NCT03874559n/a1 site📍 Kansas City University of Kansas Medical Center · Tests: Blood Draw Regorafenib With Low-dose Chemotherapies and Aspirin Followed by Standard Chemotherapies in Metastatic Colorectal Cancer NCT05462613Phase 2, Phase 316 sites📍 Besançon📍 Clermont-Ferrand📍 Créteil Centre Hospitalier Universitaire de Besancon · Tests: quality of life questionnaires, Blood sample, Regorafenib, Metronomic chemotherapies, Aspirin EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors NCT07410676Phase 1, Phase 21 site📍 Beijing Essen Biotech · Tests: EBNK-001 + IL-15 + Pembrolizumab Somatostatin Plus Clear Liquid Diet Versus Diverting Stoma in Patients With Rectal Cancer Undergoing Ultra-Low Anterior Resection NCT07605611NA3 sites📍 Ezhou📍 Wuhan📍 Wuhan Tongji Hospital · Tests: Somatostatin, Clear Liquid Diet, Prophylactic Diverting Stoma Neoadjuvant Long-course Chemoradiation Plus PD-1 Blockade for Mid-low Locally Advanced Rectal Cancer NCT05245474Phase 28 sites📍 Beijing📍 Beijing📍 Beijing Beijing Friendship Hospital · Tests: Long-course chemoradiation, with or without Tislelizumab (PD-1 inhibitor) MRD-guided Deferred Adjuvant Therapy in Resectable Early-stage Colon Cancer NCT06204484NA1 site📍 Guangzhou Sun Yat-sen University · Tests: CAPEOX adjuvant therapy, deferred CAPEOX adjuvant therapy, mFOLFOXIRI intensive adjuvant therapy Effect of Thread Embedding Acupuncture on Postoperative Ileus Recovery After Colorectal Cancer Surgery: A Multicenter Randomized Controlled Trial NCT07071987NA1 site📍 Yangzhou Northern Jiangsu People's Hospital · Tests: Thread Embedding Acupuncture+Electroacupuncture, Electroacupuncture Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections NCT07351071NA10 sites📍 New Haven📍 Tampa📍 Marietta Medtronic - MITG · Tests: Signia™ circular stapler with Tri-Staple™ Technology (Signia™ Circular Stapling system) Zanzalintinib Alone or in Combination With Pembrolizumab and Berahyaluronidase Alfa in Participants With Colorectal Cancer With Molecular Residual Disease NCT07750158Phase 313 sites📍 Council Bluffs📍 Grand Island📍 Grand Island Exelixis · Tests: Zanzalintinib, Pembrolizumab (+) Berahyaluronidase alfa, Placebo Personalized Care Pathways for Bowel Symptoms in Rectal Cancer Patients_contributing Factors (Treatable) NCT06914245NA1 site📍 Leuven KU Leuven · Tests: Electronic bowel diary, Faecal Incontinence Quality of Life questionnaire (FIQL), EuroQoL 5 dimensions, 5 levels (EQ-5D… Biomarkers for Predicting Neoadjuvant Chemoradio-resistance for Middle-low Advanced Rectal Cancer NCT03573791n/a2 sites📍 Wuhan📍 Wuhan Union Hospital, Tongji Medical College, Huazhong University… A Randomised Clinical Investigation to Assess Efficacy of Low Volume Transanal Irrigation by Qufora® IrriSedo MiniGo Versus Conservative Treatment for Low Anterior Resection Syndrome Patients NCT06923150n/a9 sites📍 Amiens📍 Besançon📍 Bordeaux Qufora A/S PARLAR-02 Trial：Modified Transanal Drainage Tube Use for Preventing Anastomotic Leakage NCT07036588NA1 site📍 Yuzhong Third Military Medical University · Tests: Modified Transanal Drainage Tube Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer NCT07448142Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: Low-dose radiotherapy, Pucotenlimab, CAPEOX/XELOX Tumor Local Excision +Postoperative Adjuvant Chemoradiotherapy for T1-2N0M0 Low/Ultra-Low Rectal Cancer NCT06949098Phase 21 site📍 Shijiazhuang Hebei Medical University Fourth Hospital · Tests: Local Tumor Resection, Radiotherapy, Chemotherapy
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