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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Low-Grade Glioma

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma NCT04166409Phase 3132 sites📍 Birmingham📍 Mesa📍 Phoenix National Cancer Institute (NCI) · Tests: Biospecimen Collection, Carboplatin, Echocardiography Test, Magnetic Resonance Imaging, Questionnaire Administration HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer) NCT06930846NA1 site📍 Lebanon Dartmouth-Hitchcock Medical Center · Tests: HOBSCOTCH-CA A Randomized Trial of Delayed Radiotherapy in Patients Low-grade Oligodendrogliomas Requiring a Treatment Other Than Surgery NCT04702581Phase 326 sites📍 Amiens📍 Angers📍 Bordeaux Hospices Civils de Lyon · Tests: PCV chemotherapy, Radiotherapy and PCV chemotherapy Metabolomics and Transcriptomics of Low- and High-Grade Gliomas NCT07832734n/a1 site📍 Milan I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio Binimetinib in Patients With BRAF Fusion-positive Low-grade Glioma or Pancreatic Cancer (Perfume) NCT06159478Phase 26 sites📍 Kashiwa📍 Sapporo📍 Kyoto National Cancer Center, Japan · Tests: Binimetinib 15 MG NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors NCT07664176Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: NeuroNavigation-Guided Focused Ultrasound (NgFUS), Lumason, Nivolumab Monitoring of Patients With Low-grade Gliomas Using Circulating miRNA NCT06610851n/a1 site📍 Caen University Hospital, Caen · Tests: Blood sample MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas NCT06712875Phase 1, Phase 23 sites📍 Washington D.C.📍 Chicago📍 New York Ann & Robert H Lurie Children's Hospital of Chicago · Tests: Trametinib and Nivolumab, Dabrafenib, trametinib, nivolumab Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma NCT07506239NA1 site📍 San Francisco University of California, San Francisco · Tests: Laser Interstitial Thermal Therapy (LITT), Magnetic resonance imaging (MRI), Questionnaires Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy NCT05180825Phase 225 sites📍 Amiens📍 Angers📍 Besançon University Hospital, Strasbourg, France · Tests: Trametinib, Vinblastine Measure of the Potential Evoked by Electric Stimulation NCT02509442NA1 site📍 Montpellier University Hospital, Montpellier · Tests: Diffusion of direct electric stimulation Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial NCT06132685Phase 21 site📍 Atlanta Emory University · Tests: Biospecimen Collection, Computed Tomography, Dexamethasone, Magnetic Resonance Imaging, Questionnaire Administration Developing Fast Pediatric Imaging NCT03761121NA3 sites📍 Boston📍 Boston📍 Boston Boston Children's Hospital · Tests: Wave-CAIPI Rehabilitation and Longitudinal Follow-up of Cognition in Adult Lower Grade Gliomas NCT03948490NA1 site📍 San Francisco University of California, San Francisco · Tests: ReMind iPad app, Healthy SMS texting, In-person cognitive rehabilitation, Telehealth cognitive rehabilitation Pilot Study of Vinblastine and Tovorafenib in Pediatric Patients With Recurrent/Progressive RAF Altered Low Grade Gliomas NCT06381570EARLY Phase 11 site📍 Toronto Daniel Morgenstern · Tests: Tovorafenib, Vinblastine SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma NCT04923126Phase 1, Phase 21 site📍 Memphis St. Jude Children's Research Hospital · Tests: Mirdametinib Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG NCT05555550EARLY Phase 11 site📍 Philadelphia Children's Hospital of Philadelphia · Tests: 18F-Fluciclovine CEST in Low-grade Glioma Study NCT05996653NA2 sites📍 Toronto📍 Toronto Sunnybrook Health Sciences Centre · Tests: Saturation Transfer (ST)-MRI Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021) NCT04485559Phase 117 sites📍 Birmingham📍 Los Angeles📍 San Diego University of California, San Francisco · Tests: Everolimus, Trametinib A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors NCT04775485Phase 235 sites📍 San Francisco📍 Washington D.C.📍 Chicago Day One Biopharmaceuticals, Inc. · Tests: Tovorafenib USPIO Enhanced MR Imaging in CNS Tumours (UMIC) NCT06572475NA1 site📍 Salford Northern Care Alliance NHS Foundation Trust · Tests: USPIO enhanced MRI ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas NCT05609994Phase 11 site📍 Durham Katy Peters, MD, PhD · Tests: PEPIDH1M vaccine + vorasidenib Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas NCT07110246Phase 212 sites📍 Birmingham📍 San Francisco📍 Washington D.C. University of California, San Francisco · Tests: Dabrafenib, Trametinib, Magnetic Resonance Imaging (MRI), Specimen Collection, Optional Lumbar puncture Patient Voice in the Treatment of Low-grade Gliomas: Use of Patient-reported Outcomes, Vorasidenib and Radiotherapy Compared NCT07547163n/a1 site📍 Milan Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Tests: Vorasidenib, Radiotherapy, active surveillance A Vaccine Trial for Low Grade Gliomas NCT02358187Phase 21 site📍 Pittsburgh James Felker · Tests: Experimental: HLA-A2 Restricted Glioma Antigen-Peptides with Poly-ICLC A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations NCT05503797Phase 270 sites📍 Beverly Hills📍 San Francisco📍 Westwood, Los Angeles Fore Biotherapeutics · Tests: Plixorafenib Radiotherapy Versus Radiotherapy Combined With Temozolomide in High-risk Low-grade Gliomas After Surgery NCT04316039Phase 2, Phase 31 site📍 Chengdu West China Hospital · Tests: Temozolomide, intensity modulated radiation therapy Feasibility of Individualized, Model-guided Optimization of Proton Beam Treatment Planning in Patients With Low Grade Glioma NCT05964569Phase 21 site📍 Heidelberg University Hospital Heidelberg · Tests: model-guided optimization of treatment plan, standard treatment plan, no optimization Registry Study on Epidemiological and Biological Disease Profile as Well as Clinical Outcome in Patients With Low Grade Gliomas NCT02686229n/a1 site📍 Ulm University of Ulm · Tests: no interventions Longitudinal Analysis of the Health-related Quality of Life in Glioma Patients NCT03849430n/a1 site📍 Leuven Universitaire Ziekenhuizen KU Leuven
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