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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Lymphatic Malformations

A Phase 2 Study of Mutant-selective PI3Kฮฑ Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study) NCT06789913Phase 240 sites๐Ÿ“ Phoenix๐Ÿ“ Little Rock๐Ÿ“ Los Angeles Relay Therapeutics, Inc. ยท Tests: RLY-2608, Placebo Molecular Studies on Hereditary Haemorrhagic Telangiectasia Families NCT00230620n/a1 site๐Ÿ“ London Imperial College London A Study to Investigate Efficacy and Safety of KP-001 Compared With Placebo in Patients Aged โ‰ฅ2 Years With Common VM, Common LM, or KTS/CLOVES Syndrome NCT07285005Phase 35 sites๐Ÿ“ Charleston๐Ÿ“ Daegu๐Ÿ“ Seoul Kaken Pharmaceutical ยท Tests: KP-001, Placebo Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders NCT06081348Phase 27 sites๐Ÿ“ Calgary๐Ÿ“ Edmonton๐Ÿ“ Halifax Holland Bloorview Kids Rehabilitation Hospital ยท Tests: Sertraline, Placebo Body Donation in HHT NCT07826845NA1 site๐Ÿ“ Essen University Hospital, Essen ยท Tests: body donation in HHT TSC Biosample Repository and Natural History Database NCT05676099n/a26 sites๐Ÿ“ Birmingham๐Ÿ“ Loma Linda๐Ÿ“ Los Angeles National Tuberous Sclerosis Association ยท Tests: Phlebotomy, Buccal (cheek) swab, Genetic Testing, Tissue donation after routine clinical procedure A Prospective Natural History Study of Lymphatic Anomalies NCT05731141n/a2 sites๐Ÿ“ Bethesda๐Ÿ“ Philadelphia Eunice Kennedy Shriver National Institute of Child Health aโ€ฆ A Trial to Assess the Efficacy and Safety of Engasertib in Participants With Moderate to Severe Hereditary Hemorrhagic Telangiectasia (HHT) NCT07743671Phase 34 sites๐Ÿ“ Chicago๐Ÿ“ Indianapolis๐Ÿ“ Rochester Vaderis Therapeutics AG ยท Tests: Engasertib, Placebo GROWing Up With Rare GENEtic Syndromes NCT04463316n/a1 site๐Ÿ“ Rotterdam dr. Laura C. G. de Graaff-Herder ยท Tests: Retrospective file studies Pregnancy in Women With Rare Multisystemic Vascular Diseases: COGRare5 Study NCT04194619n/a37 sites๐Ÿ“ Angers๐Ÿ“ Bordeaux๐Ÿ“ Bordeaux Hospices Civils de Lyon ยท Tests: Questionnaire Identification of Biomarkers for Patients with Vascular Anomalies NCT03001180n/a2 sites๐Ÿ“ Boston๐Ÿ“ Cincinnati Children's Hospital Medical Center, Cincinnati Comprehensive HHT Outcomes Registry of the United States (CHORUS) NCT06259292n/a16 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ San Francisco Cure HHT Influence of Hypoxic Induced Factors in Patients With Hereditary Hemorrhagic Telangiectasia NCT04469517n/a1 site๐Ÿ“ Essen University Hospital, Essen ยท Tests: hypoxic induced factors European Registry Study on Lymphatic Interventions NCT07131293n/a1 site๐Ÿ“ Copenhagen Copenhagen University Hospital, Rigshospitalet ยท Tests: Lymphatic intervention A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders NCT06092346n/a1 site๐Ÿ“ Bethesda National Human Genome Research Institute (NHGRI) Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a2 sites๐Ÿ“ Sioux Falls๐Ÿ“ Sydney Sanford Health Familial Investigations of Childhood Cancer Predisposition NCT03050268n/a1 site๐Ÿ“ Memphis St. Jude Children's Research Hospital Vascular Lab Resource (VLR) Biorepository NCT05628948n/a1 site๐Ÿ“ Cleveland The Cleveland Clinic Quality of Life in Pediatric Participants With HHT NCT07474428n/a1 site๐Ÿ“ Cincinnati Ashley Nelson Case Notes Review on Patients With Hereditary Haemorrhagic Telangiectasia NCT00230685n/a1 site๐Ÿ“ London Imperial College London Study of the Disease Process of Lymphangioleiomyomatosis NCT00001465n/a1 site๐Ÿ“ Bethesda National Heart, Lung, and Blood Institute (NHLBI) ยท Tests: Toshibia Aquilion One CT Lymphatic Anomalies Registry for the Assessment of Outcome Data NCT02399527n/a1 site๐Ÿ“ Boston Boston Children's Hospital Prospective Study of Antiplatelet and Anticoagulation Therapy in Hereditary Haemorrhagic Telangiectasia NCT05641142NA18 sites๐Ÿ“ Angers๐Ÿ“ Bordeaux๐Ÿ“ Boulogne-Billancourt University Hospital, Clermont-Ferrand ยท Tests: monitoring the use of anticoagulant and/or antiplatelet therapy in patients with osler rendering disease Quantitative Susceptibility Biomarker and Brain Structural Property for Cerebral Cavernous Malformation Related Epilepsy NCT04076449n/a2 sites๐Ÿ“ Beijing๐Ÿ“ Beijing yuanli Zhao The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk Assessment NCT07643896n/a9 sites๐Ÿ“ Phoenix๐Ÿ“ Riverside๐Ÿ“ West Covina BillionToOne Inc. DIAG723 in Adults With Hereditary Hemorrhagic Telangiectasia NCT07623525Phase 1, Phase 211 sites๐Ÿ“ Camperdown๐Ÿ“ Randwick๐Ÿ“ Herston Diagonal Therapeutics, Inc. ยท Tests: DIAG723, Placebo Study on Treatment Decision-Making and Prognostic Follow-Up for Untreated Cerebral Cavernous Malformations NCT06214767n/a1 site๐Ÿ“ Beijing Beijing Tiantan Hospital Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations NCT03243019Phase 22 sites๐Ÿ“ Lille๐Ÿ“ Paris University Hospital, Lille ยท Tests: rapamycin, MRI, Rapamycin dosage A Prospective Study on the Treatment of cLM Based on ICG Imaging NCT06275022NA1 site๐Ÿ“ Nanjing Nanjing Children's Hospital ยท Tests: Inflow occlusion with perforation of septation and sclerotherapy, Perforation of septation and sclerotherapy, Indocyaniโ€ฆ Institutional Registry of Rare Diseases NCT06573723n/a1 site๐Ÿ“ Buenos Aires Hospital Italiano de Buenos Aires
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