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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Malignant Glioma of Brain

Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions NCT04047264NA1 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Microdialysis, Magnetic Resonance Imaging, Computed Tomography Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA NCT01269853Phase 1, Phase 21 site๐Ÿ“ New York Northwell Health ยท Tests: Bevacizumab, Bevacizumab Injection of Active Allogeneic Natural Killer Cells in Patients With Gliomas NCT06687681Phase 21 site๐Ÿ“ Tehran Marzieh Ebrahimi ยท Tests: NK cell therapy Evaluation of Clinical Efficacy and Safety of Specific Mode Electroacupuncture Stimulation for Paclitaxel Across BBB Delivery in Patients With Postoperative Recurrence of Malignant Glioma: A Single-arm Trial NCT06818331Phase 21 site๐Ÿ“ China The Third Affiliated hospital of Zhejiang Chinese Medical Uโ€ฆ ยท Tests: SMES+PTX, Paclitaxel, Specific mode electroacupuncture stimulation Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG) NCT07210632EARLY Phase 11 site๐Ÿ“ Nashville Eben Rosenthal ยท Tests: Nivolumab, Nivolumab-IRDye800 Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors NCT04908709NA3 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Magnetic Resonance Spectroscopic Imaging, Proton Therapy Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloudยฎ Device to Treat Malignant Brain Tumors in Pediatric Patients NCT05293197Phase 13 sites๐Ÿ“ Paris๐Ÿ“ Paris๐Ÿ“ Villejuif Assistance Publique - Hรดpitaux de Paris ยท Tests: SonoCloudยฎ (9 transducers) Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy NCT07179328Phase 11 site๐Ÿ“ Toronto Sunnybrook Health Sciences Centre ยท Tests: Focused Ultrasound Next Generation Dome Helmet, Definityยฎ Vial for (Perflutren Lipid Microsphere) Injectable Suspension ABY-029 Glioma Trial NCT07063693Phase 11 site๐Ÿ“ Lebanon Dartmouth-Hitchcock Medical Center ยท Tests: ABY-029 NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors NCT07664176Phase 11 site๐Ÿ“ Washington D.C. Children's National Research Institute ยท Tests: NeuroNavigation-Guided Focused Ultrasound (NgFUS), Lumason, Nivolumab Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188Phase 1, Phase 21 site๐Ÿ“ Bethesda National Institute of Neurological Disorders and Stroke (NIโ€ฆ ยท Tests: LMP744, Conventional Surgery or Biopsy Chronic CED of TPT for Recurrent Malignant Glioma NCT06666712Phase 11 site๐Ÿ“ New York Jeffrey N. Bruce ยท Tests: Topotecan Phase 1 Study of Locoregional Injections of Ex Vivo Expanded Natural Killer Cells NCT04254419Phase 11 site๐Ÿ“ Columbus Nationwide Children's Hospital ยท Tests: NK cells Concurrent Fluorescence and Sonographically Guided Eradication of High-grade Gliomas and Metastases NCT05474573NA1 site๐Ÿ“ Moscow Sklifosovsky Institute of Emergency Care ยท Tests: Combined ultrasound and fluorescence-guided brain tumor resection, Fluorescence-guided brain tumor resection C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B) NCT04099797Phase 11 site๐Ÿ“ Houston Baylor College of Medicine ยท Tests: C7R-GD2.CART cells (IV and ICV infusion), C7R-GD2.CART cells (IV and ICV infusion) SeOuL cOhort of Brain Tumor MONitoring Study (SOLOMON) NCT05254197n/a1 site๐Ÿ“ Seoul Seoul National University Hospital A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites๐Ÿ“ Washington D.C.๐Ÿ“ Gainesville University of Florida ยท Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP liโ€ฆ Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial NCT06132685Phase 21 site๐Ÿ“ Atlanta Emory University ยท Tests: Biospecimen Collection, Computed Tomography, Dexamethasone, Magnetic Resonance Imaging, Questionnaire Administration Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery NCT03510208Phase 1, Phase 21 site๐Ÿ“ Palo Alto Stanford University ยท Tests: Near-Infrared Fluorescence Imaging, Panitumumab, Panitumumab-IRDye800, POINPOINT-IR9000 Characterization of the Blood-Brain Barrier in High-Grade Glioma Through Immunohistochemical, Transcriptional, Fluorescein and Radiological Analyses NCT07731555NA1 site๐Ÿ“ Beaumont Patrick Morris ยท Tests: Multimodal Blood Brain Barrier Assessment 5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours NCT06630260Phase 1, Phase 23 sites๐Ÿ“ Cambridge๐Ÿ“ Sutton๐Ÿ“ Sutton Institute of Cancer Research, United Kingdom ยท Tests: Avutometinib, Defactinib, Temozolomide SIMPLIFication of Care Pathways for Patients With Rare Brain Tumors Through Artificial Intelligence NCT06878469NA2 sites๐Ÿ“ Milan๐Ÿ“ Lโ€™Aquila Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta ยท Tests: RehaCom DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers. NCT05770544Phase 2, Phase 327 sites๐Ÿ“ Belfast๐Ÿ“ Birmingham๐Ÿ“ Birmingham Cancer Research UK ยท Tests: Entrectinib Clinical Study on the Treatment of Malignant Brain Glioma by QH104 Cell Injection NCT06018363Phase 1, Phase 21 site๐Ÿ“ Suzhou Dushu Lake Hospital Affiliated to Soochow University ยท Tests: Allogenic B7-H3 CAR-ฮณฮดT cell(QH104) HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors NCT03911388Phase 13 sites๐Ÿ“ Birmingham๐Ÿ“ St Louis๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: G207 Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG NCT05555550EARLY Phase 11 site๐Ÿ“ Philadelphia Children's Hospital of Philadelphia ยท Tests: 18F-Fluciclovine Mapping of Electrical Properties in the Brain NCT06470711n/a1 site๐Ÿ“ Scottsdale Mayo Clinic ยท Tests: Non-Interventional Study Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss NCT06810544Phase 1, Phase 215 sites๐Ÿ“ Scottsdale๐Ÿ“ Irvine๐Ÿ“ Los Angeles Tango Therapeutics, Inc. ยท Tests: TNG456, abemaciclib Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant NCT05843253Phase 220 sites๐Ÿ“ Aurora๐Ÿ“ Washington D.C.๐Ÿ“ Chicago Nationwide Children's Hospital ยท Tests: Ribociclib, Everolimus, Temozolomide (TMZ) The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma NCT06273176n/a8 sites๐Ÿ“ San Francisco๐Ÿ“ Boston๐Ÿ“ Leuven Erasmus Medical Center ยท Tests: Awake mapping under local anesthesia, Asleep mapping under general anesthesia, Resection under general anesthesia withoโ€ฆ
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