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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Metastatic Malignant Neoplasm

A Study to Evaluate Efficacy, and Safety of QL2107 Plus Chemo and Compare With Keytruda in Participants With IV nqNSCLC NCT06754644Phase 31 site📍 Jinan Qilu Pharmaceutical Co., Ltd. · Tests: QL2107, Pemetrexed, Carboplatin, Keytruda® Standard Systemic Therapy Combined With High/Low-dose Radiotherapy Plus Toripalimab for Metastatic Colorectal Cancer NCT06525428Phase 21 site📍 Shanghai Fudan University · Tests: standard systemic therapy combined with high/low-dose radiotherapy plus toripalimab Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment NCT05661461Phase 12 sites📍 San Antonio📍 West Valley City Aadi Bioscience, Inc. · Tests: nab-sirolimus Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 Inhibitor NCT05933395Phase 21 site📍 Lebanon Dartmouth-Hitchcock Medical Center · Tests: Fulvestrant, Neratinib, Alpelisib, Everolimus, Abemaciclib Elacestrant in Patients With ER+ HER2- ESR1-mutated Locally Advanced or Metastatic Breast Cancer NCT07563595n/a3 sites📍 Freiburg im Breisgau📍 Paderborn📍 Ravensburg iOMEDICO AG · Tests: Elacestrant, Standard of care (Investigator Choice) A Study of BL-M05D1 in Patients With Locally Advanced or Metastatic Solid Tumors NCT06349811Phase 11 site📍 Beijing Sichuan Baili Pharmaceutical Co., Ltd. · Tests: BL-M05D1 ioMRI in the Surgery of Brain Metastases. NCT07197632NA1 site📍 Munich Technical University of Munich · Tests: Surgery with intraoperative MRI The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation NCT06843551Phase 21 site📍 Miami Benjamin Spieler · Tests: Stereotactic Body Radiation Therapy, Botensilimab, Balstilimab Combination Study of Antibiotics With Enzalutamide (PROMIZE) NCT06126731Phase 1, Phase 22 sites📍 Bellinzona📍 Sutton Institute of Cancer Research, United Kingdom · Tests: Enzalutamide 40mg, Amoxicillin 500mg, Metronidazole 400mg, Vancomycin 125mg, Ciprofloxacin 500g Regional Lymph Node Metastasis and Survival Outcomes in Advanced HCC NCT06876753n/a2 sites📍 Nanjing📍 Nanjing Zhongda Hospital Neoadjuvant Stereotactic Radiotherapy for Brain Metastasis NCT06933199NA4 sites📍 Ostrava📍 Brno📍 Hradec Králové University Hospital Ostrava · Tests: Neoadjuvant Stereotactic Radiotherapy (NaSRT), Postoperative Stereotactic Radiotherapy (SRT) MT027 in Patients With Advanced Peritoneal Malignancies or Abdominal Metastatic Solid Tumors NCT06912152Phase 11 site📍 Hangzhou Zhejiang University · Tests: MT027 CAR-T cells Artificial Intelligence-based Platform, Integrating Pathologic, Imaging and Molecular Profiles of Prostate Cancer NCT06468332n/a1 site📍 Novara Azienda Ospedaliero Universitaria Maggiore della Carita ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR) NCT06415487Phase 19 sites📍 San Diego📍 Denver📍 Nashville Acepodia Biotech, Inc. · Tests: Cyclophosphamide, Fludarabine, ACE2016, Pembrolizumab Safety and Feasibility of Intraoperative Visualization With Cytalux in Children NCT06235125Phase 11 site📍 Chicago Ann & Robert H Lurie Children's Hospital of Chicago · Tests: Cytalux Study Evaluating DNA Double-strand Breaks (DSBs) REpair Factors (POLQ, Shieldin Complex and 53BP1) Expression as Biomarker of PARP Inhibitor Resistance in Patients With Deleterious Germline Mutation in BRCA 1/2 and HER2-negative, Metastatic or Locally Advanced Breast Cancer. NCT05378204NA25 sites📍 Bordeaux📍 Caen📍 Clermont-Ferrand Institut Claudius Regaud · Tests: Main study:, Sub-study: DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer NCT06275958Phase 336 sites📍 's-Hertogenbosch📍 Alkmaar📍 Amstelveen Leiden University Medical Center · Tests: Doublet Chemotherapy, Standard Dose (100%), Doublet Chemotherapy, Dose-reduced (75%), Monotherapy, Standard Dose (100%)… A Study to Investigate ANS03 in Participants With Locally Advanced or Metastatic Solid Tumors NCT06716138Phase 15 sites📍 New York📍 Fuzhou📍 Guangzhou Avistone Biotechnology Co., Ltd. · Tests: ANS03 ORIENT-31 Regimen in Combination With SBRT for EGFR-mutant Metastatic NSCLC After First-line Third-generation EGFR-TKIs NCT06775743Phase 21 site📍 Shanghai Fudan University · Tests: ORIENT-31 regimen, SBRT The Safety, Efficacy, and Immune Response of Multimodal Thermal Therapy in the Treatment of Malignant Liver Tumors NCT07159048NA1 site📍 Shanghai Fudan University · Tests: Multimodal Tumor Thermal Therapy System, Radiofrequency Ablation System or Microwave Ablation System Breast Cancer: Axillary Conservation After Neoadjuvant Chemotherapy in Micro Metastatic Sentinel Lymph Nodes. NCT04019678NA1 site📍 Rozzano Istituto Clinico Humanitas · Tests: Omission of Axillary dissection A Study of GNC-077 in Patients With Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors NCT06609187Phase 11 site📍 Beijing Sichuan Baili Pharmaceutical Co., Ltd. · Tests: GNC-077 Safety and Early Efficacy of Radical Prostatectomy for Newly Diagnosed Very High Risk Locally Advanced and Oligometastatic Prostate Cancer NCT02971358NA1 site📍 Vienna Medical University of Vienna · Tests: Radical prostatectomy EGFR Antibody Combined With PD-1 Inhibitor and Chemotherapy in R/M Nasopharyngeal Carcinoma NCT06802835Phase 1, Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: EGFR Antibody, PD-1 antibody, Gemcitabine, Cisplatin, IMRT MAESTRO Study: Metabolic Imaging to Improve Patient-Specific Therapy Outcomes NCT04534543NA2 sites📍 Amsterdam📍 Utrecht Academisch Medisch Centrum - Universiteit van Amsterdam (AM… · Tests: MRI/Spectroscopy A Phase I Study of CFT8919 in Patients With Advanced NSCLC NCT06641609Phase 11 site📍 Hangzhou Betta Pharmaceuticals Co., Ltd. · Tests: Dose-Escalation (Phase Ia) CFT8919 capsule, Dose-Expansion (Phase Ib) CFT8919 capsule, Cohort-Expansion (Phase Ic) CFT8… Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel NCT06483555Phase 1, Phase 21 site📍 Chapel Hill UNC Lineberger Comprehensive Cancer Center · Tests: Gemcitabine, Nab paclitaxel, Erlotinib, NALIRIFOX, Folfirinox Testing How the Body Responds to the Drug CX-5461 (Pidnarulex) in Patients With Metastatic Solid Cancers NCT06606990Phase 11 site📍 Bethesda National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test, Magnetic Resonance Imaging Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC) NCT07217717Phase 319 sites📍 Cerritos📍 Duarte📍 Irvine SOFIE · Tests: [18F]FAPI-74 PET/CT A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation. NCT05967689Phase 280 sites📍 Birmingham📍 Duarte📍 Boston Taiho Oncology, Inc. · Tests: TAS6417, CYP Cocktail, Transporter Cocktail
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