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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Neoplastic Syndromes, Hereditary

Treatment of Newly Diagnosed Patient's With Wilm's Tumor Requiring Abdominal Radiation Delivered With Proton Beam Irradiation NCT04968990Phase 21 site📍 Memphis St. Jude Children's Research Hospital · Tests: Proton Beam Radiation (PBRT), DD-4A Chemotherapy Regimen, Complete Surgical Resection, Surgical Resection, Partial Neph… The NF Registry Sponsored by the Children's Tumor Foundation NCT01885767n/a1 site📍 New York The Children's Tumor Foundation Efficacy and Safety of Rapamycin Versus Vigabatrin in the Prevention of Tuberous Sclerosis Complex Symptoms in Infants NCT04987463Phase 2, Phase 32 sites📍 Warsaw📍 Warsaw Katarzyna Kotulska · Tests: Vigabatrin, Rapamycin, Placebo, Placebo A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1 NCT06541847Phase 214 sites📍 Birmingham📍 Los Angeles📍 Palo Alto Healx Limited · Tests: HLX-1502 Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST) NCT06222203n/a1 site📍 Bethesda National Cancer Institute (NCI) Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP) NCT06641310NA2 sites📍 Ann Arbor📍 Cleveland University of Michigan Rogel Cancer Center · Tests: Exercise Therapy Natural History Study of Patients With Neurofibromatosis Type 2 NCT00598351n/a1 site📍 Bethesda National Institute of Neurological Disorders and Stroke (NI… Oral Hedgehog Inhibitors in the Treatment of Basal Cell Carcinoma in the Netherlands: a Prospective Registration Study NCT05463757n/a8 sites📍 Nijmegen📍 Maastricht📍 Amsterdam Maastricht University Medical Center · Tests: Vismodegib, Sonidegib PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas NCT06961565Phase 15 sites📍 Birmingham📍 St Leonards📍 Melbourne Pasithea Therapeutics Corp. · Tests: PAS-004 Tablets Trial of Combined Obstetric Carrier Screening and Hereditary Cancer Screening NCT07052266NA5 sites📍 Brooklyn📍 Brooklyn📍 New York Weill Medical College of Cornell University · Tests: MyRisk Hereditary Cancer Test A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia NCT05849662Phase 1, Phase 221 sites📍 Phoenix📍 Los Angeles📍 San Francisco Therapeutic Advances in Childhood Leukemia Consortium · Tests: Trametinib, Azacitidine, Fludarabine, Cytarabine Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis NCT06950385Phase 329 sites📍 Arcadia📍 New Haven📍 Washington D.C. Rapamycin Holdings Inc. · Tests: eRapa (encapsulated rapamycin), Placebo Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors NCT04074135Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: 68-Gallium DOTATATE Metabolomics and Genetic Diagnosing Pancreatic Neuroendocrine Tumors in MEN1 Patients NCT03048266n/a1 site📍 Houston M.D. Anderson Cancer Center An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis NCT06557733Phase 24 sites📍 Phoenix📍 Rochester📍 Salt Lake City National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, EP2/EP4 Antagonist TPST-1495, Esophagogastroduodenoscopy, Gastrointestinal En… Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome NCT07220239NA1 site📍 Boston Jessica D. St. Laurent, MD · Tests: Menstrual cup use Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1 Using Novel Magnetic Resonance Imaging Techniques Paired With Artificial Intelligence NCT04763109NA1 site📍 Los Angeles Nicole Baca · Tests: Whole-body Magnetic Resonance Imaging Integration of the PD-L1 Inhibitor Atezolizumab and WT1/DC Vaccination Into Platinum/Pemetrexed-based First-line Treatment for Epithelioid Malignant Pleural Mesothelioma NCT05765084Phase 1, Phase 23 sites📍 Edegem📍 Ghent📍 Sint-Niklaas University Hospital, Antwerp · Tests: Dendritic cell vaccination, Atezolizumab, Platinum/pemetrexed based chemotherapy MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies NCT05735717Phase 21 site📍 Minneapolis Masonic Cancer Center, University of Minnesota · Tests: Fludarabine, Busulfan, Melphalan, Rituximab, Levetiracetam Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders NCT06147414n/a1 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: Blood sample Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders NCT06081348Phase 27 sites📍 Calgary📍 Edmonton📍 Halifax Holland Bloorview Kids Rehabilitation Hospital · Tests: Sertraline, Placebo The Intersection of Oncology Care and Worker Well-Being NCT05250284n/a1 site📍 Aurora University of Colorado, Denver · Tests: WellBQ, PROMIS TSC Biosample Repository and Natural History Database NCT05676099n/a26 sites📍 Birmingham📍 Loma Linda📍 Los Angeles National Tuberous Sclerosis Association · Tests: Phlebotomy, Buccal (cheek) swab, Genetic Testing, Tissue donation after routine clinical procedure Implementation of Population Cancer Genetic Services in Federally Qualified Health Centers (FQHC) NCT05664867NA1 site📍 Chicago University of Illinois at Chicago · Tests: Mainstream Genetic Testing Model, Enhanced Standard of Care Model Tailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health Literacy NCT07233408NA1 site📍 Boston Massachusetts General Hospital · Tests: NF1 Educational Videos, Peer Navigator, Letters about NF1 Care Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma NCT00040352n/a2 sites📍 Bethesda📍 Bethesda National Cancer Institute (NCI) First in Human Pilot Study to Assess the Safety and Efficacy of Dendritic Cells Loaded With Frameshift Derived Neopeptides for the Prevention of Cancer in of Lynch Syndrome Carriers NCT07163403Phase 11 site📍 Barcelona Fundacion Clinic per a la Recerca Biomédica · Tests: Autologous Tolerogenic Dendritic cells Glioma Developmental and HyperActive Ras Tumor (DHART) Board NCT05489783n/a7 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells NCT07148050Phase 11 site📍 Seattle Seattle Children's Hospital · Tests: SC-CAR.GPC3xIL15.21 CAR T cells Development of Patient-Reported Outcome Measures Assessing Tumor Visibility and Appearance Concerns in Neurofibromatosis Type 1: A Qualitative Study NCT06880991n/a1 site📍 Bethesda National Cancer Institute (NCI) · Tests: Arm 1
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