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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Neurofibromas

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma NCT04166409Phase 3132 sites📍 Birmingham📍 Mesa📍 Phoenix National Cancer Institute (NCI) · Tests: Biospecimen Collection, Carboplatin, Echocardiography Test, Magnetic Resonance Imaging, Questionnaire Administration Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors NCT04222413Phase 12 sites📍 Fairway📍 Bethesda National Cancer Institute (NCI) · Tests: Metarrestin The NF Registry Sponsored by the Children's Tumor Foundation NCT01885767n/a1 site📍 New York The Children's Tumor Foundation A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1 NCT06541847Phase 214 sites📍 Birmingham📍 Los Angeles📍 Palo Alto Healx Limited · Tests: HLX-1502 Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST) NCT06222203n/a1 site📍 Bethesda National Cancer Institute (NCI) Natural History Study of Patients With Neurofibromatosis Type 2 NCT00598351n/a1 site📍 Bethesda National Institute of Neurological Disorders and Stroke (NI… MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma NCT06277154Phase 21 site📍 Guangzhou HRYZ Biotech Co. · Tests: MASCT-I, Doxorubicin, Ifosfamide PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas NCT06961565Phase 15 sites📍 Birmingham📍 St Leonards📍 Melbourne Pasithea Therapeutics Corp. · Tests: PAS-004 Tablets A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia NCT05849662Phase 1, Phase 221 sites📍 Phoenix📍 Los Angeles📍 San Francisco Therapeutic Advances in Childhood Leukemia Consortium · Tests: Trametinib, Azacitidine, Fludarabine, Cytarabine Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1 Using Novel Magnetic Resonance Imaging Techniques Paired With Artificial Intelligence NCT04763109NA1 site📍 Los Angeles Nicole Baca · Tests: Whole-body Magnetic Resonance Imaging MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies NCT05735717Phase 21 site📍 Minneapolis Masonic Cancer Center, University of Minnesota · Tests: Fludarabine, Busulfan, Melphalan, Rituximab, Levetiracetam Evaluation of TQ-B3234 Capsules in Patients With Symptomatic, Non-Surgical Type 1 Neurofibromatosis-Associated Plexiform Neurofibromas NCT07407803Phase 329 sites📍 Hefei📍 Beijing📍 Beijing Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Tests: TQ-B3234 capsules, TQ-B3234 placebo Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders NCT06147414n/a1 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: Blood sample Tailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health Literacy NCT07233408NA1 site📍 Boston Massachusetts General Hospital · Tests: NF1 Educational Videos, Peer Navigator, Letters about NF1 Care Glioma Developmental and HyperActive Ras Tumor (DHART) Board NCT05489783n/a7 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center Development of Patient-Reported Outcome Measures Assessing Tumor Visibility and Appearance Concerns in Neurofibromatosis Type 1: A Qualitative Study NCT06880991n/a1 site📍 Bethesda National Cancer Institute (NCI) · Tests: Arm 1 GROWing Up With Rare GENEtic Syndromes NCT04463316n/a1 site📍 Rotterdam dr. Laura C. G. de Graaff-Herder · Tests: Retrospective file studies A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1) NCT06507748NA2 sites📍 Washington D.C.📍 Bethesda National Cancer Institute (NCI) · Tests: AlgometRx Nociometer(R) IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS) NCT06849986Phase 21 site📍 Shanghai Fudan University · Tests: Tislelizumab+liposomal doxorubicin+ifosfamide Observational Study of the Real-world Effectiveness and Safety of Selumetinib Treating Adult Patients With Neurofibromatosis Type 1 (NF1) Who Have Symptomatic, Inoperable Plexiform Neurofibroma (PN) NCT07888517n/a26 sites📍 Beijing📍 Changchun📍 Changsha AstraZeneca NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) NCT06239272Phase 1, Phase 27 sites📍 Atlanta📍 Chicago📍 Baton Rouge St. Jude Children's Research Hospital · Tests: Surgical resection, Proton beam radiation therapy, Pazopanib, Ifosfamide, Doxorubicin Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST NCT06735820Phase 1, Phase 22 sites📍 Washington D.C.📍 Dallas AeRang Kim · Tests: APG-115, Selumetinib B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR) NCT04897321Phase 11 site📍 Memphis St. Jude Children's Research Hospital · Tests: Fludarabine, Cyclophosphamide, MESNA, B7-H3 CAR T cells Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors NCT03141021n/a13 sites📍 Tampa📍 Baltimore📍 Bethesda Washington University School of Medicine Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ... NCT02390752Phase 11 site📍 Bethesda National Cancer Institute (NCI) · Tests: TURALIO(R) Familial Investigations of Childhood Cancer Predisposition NCT03050268n/a1 site📍 Memphis St. Jude Children's Research Hospital Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1 NCT06188741Phase 215 sites📍 Birmingham📍 Los Angeles📍 Palo Alto University of Alabama at Birmingham · Tests: Selumetinib Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2) NCT04374305Phase 26 sites📍 Los Angeles📍 Miami📍 Indianopolis Scott R. Plotkin, MD, PhD · Tests: Brigatinib, Neratinib, Retifanlimab, Bevacizumab Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas NCT05253131Phase 21 site📍 Birmingham University of Alabama at Birmingham · Tests: Selumetinib + ZEN-3694 ± Durvalumab Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF). NCT06159166Phase 1, Phase 21 site📍 Baltimore Johns Hopkins University · Tests: Mirdametinib
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