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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Organ Preservation

Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery NCT03051464Phase 2, Phase 34 sites📍 Dallas📍 Montreal📍 Montreal Sir Mortimer B. Davis - Jewish General Hospital · Tests: Complete responders and Non-complete responders, Chemoradiation + EBRT Boost, Chemoradiation + HDRBT Boost Evaluation of Thiosulfate Enhanced Organ Preservation Solution in Kidney Transplantation NCT06288152NA1 site📍 London Alp Sener · Tests: Sodium Thiosulfate Immune Checkpoint Inhibitors for Organ Preservation in Non-metastatic dMMR/MSI-H Gastric or Colon Cancers NCT06580574Phase 21 site📍 Beijing Peking University · Tests: PD1/PDL1 antibody monotherapy, up to 24 weeks, Intensive immunotherapy plus anti-VEGF treatment, up to 24 weeks, Radica… Towards Cure Via Only Ultra-short ICB in CSCC NCT06823479Phase 25 sites📍 Maastricht📍 Amsterdam📍 Amsterdam The Netherlands Cancer Institute · Tests: Nivolumab, Ipilumimab Nordic ORgan Preservation Pilot Approach Nonrandomised Single-Arm Trial for Non-Operative Management of Rectal Cancer NCT06328361NA13 sites📍 Tallinn📍 Tallinn📍 Tallinn Tampere University Hospital · Tests: Nonoperative surveillance Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer. NCT06758830Phase 2, Phase 31 site📍 Vilnius National Cancer Center Affiliate of Vilnius University Hosp… · Tests: Radiation Therapy, Chemoradiotherapy, Consolidation Chemotherapy, Surgery, Part two LECS Combined With LSNNS for Early Gastric Cancer (LENS Trial) NCT07857668n/a1 site📍 Beijing Peking University People's Hospital · Tests: Procedure: LECS combined with LSNNS Hyperthermia With Chemoradiotherapy in Rectal Cancer NCT06831981NA2 sites📍 Tübingen📍 Tübingen University Hospital Tuebingen · Tests: Hyperthermia, Radiotherapy, Chemotherapy with 5-fluorouracil, Consolidation chemotherapy with FOLFOX European Larynx Organ Preservation Study (ELOS) [MK-3475-C44] NCT06137378Phase 29 sites📍 Mannheim📍 Ulm📍 München University of Leipzig · Tests: KEYTRUDA® Organ Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local Excision NCT05772923NA7 sites📍 Nijmegen📍 Eindhoven📍 Amsterdam The Netherlands Cancer Institute · Tests: Contact x-ray brachytherapy, Local excision Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer NCT07448142Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: Low-dose radiotherapy, Pucotenlimab, CAPEOX/XELOX MRI-Guided Adaptive Radiation Therapy for Organ Preservation in Rectal Cancer NCT04808323Phase 11 site📍 Milwaukee Medical College of Wisconsin · Tests: Capecitabine, Initial Dose of Radiation before Dose Escalation, Cohort A: Dose Escalation Radiation, Cohort B: Dose Esc… Organ Preservation in Locally Advanced Rectal Cancer NCT03064646NA1 site📍 Elche Fundación para el Fomento de la Investigación Sanitaria y B… · Tests: Organ Preservation Local Excision for Organ Preservation in Early REctal Cancer With No Adjuvant Treatment NCT05927584n/a1 site📍 Madrid Fundación de Investigación Biomédica - Hospital Universitar… · Tests: Transanal local excision Adaptive Radiation Boost for Rectal Cancer NCT07221058Phase 11 site📍 Philadelphia Fox Chase Cancer Center · Tests: Adaptive Radiotherapy Boost Organ Preservation in Rectal AdenoCa Using Hypofractionated Pelvic RT(Hypo-OPRA) NCT06991465Phase 21 site📍 Montreal Neil Kopek · Tests: Radiation Therapy, FOLFOX regimen, Capecitabine ZeroHeart Biopsy - Prediction of Deceased Donor Heart Transplant Performance From Organ Donors Using Pre-Transplant Biopsies - A Pilot Study NCT06982404n/a1 site📍 Vienna Medical University of Vienna · Tests: Time Zero Donor Heart Biopsy for Molecular Analysis Watch and Wait for NeoAdjuvant Concurrent Radiochemotherapy Combined With Camrelizumab in Patients With Resectable ESCC NCT05507411Phase 23 sites📍 Hanzhou📍 Hanzhou📍 Ningbo Zhejiang Cancer Hospital · Tests: Neoadjuvant Radiotherapy, Neoadjuvant Chemotherapy, Immunotherapy Active Surveillance vs Adjuvant Chemoradiotherapy for Locally Resected Intermediate-Risk T1 Rectal Cancer NCT07669298NA3 sites📍 Limoges📍 Gdansk📍 Warsaw Medical University of Gdansk · Tests: Active surveillance, Adjuvant chemoradiotherapy Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates NCT07292298Phase 23 sites📍 Aurora📍 Rochester📍 Portland University of Colorado, Denver · Tests: High Rare Dose Rectal Brachytherapy Boost Planed Organ Preservation for Low Rectal Cancer After Neoadjuvant Chemotherapy (OPLAR) NCT07070622Phase 31 site📍 Chengdu West China Hospital · Tests: patients were assigned to receive TNT or iTNT management Long-term Outcomes After Prolonged Dual Hypothermic Oxygenated Machine Perfusion of Donor Livers (DHOPEPROLONG) NCT05680246n/a1 site📍 Groningen University Medical Center Groningen · Tests: DHOPE-PRO Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer NCT04703101Phase 11 site📍 Los Angeles Jonsson Comprehensive Cancer Center · Tests: Capecitabine, Fluorouracil, Intensity-Modulated Radiation Therapy, Leucovorin, Oxaliplatin Node-Sparing Short-Course Radiation Combined With Capecitabine and PD-1/CTLA-4 for MSS Early Rectal Cancer NCT07068763Phase 21 site📍 Hangzhou Sir Run Run Shaw Hospital · Tests: Lymph-node-sparing short-course radiotherapy, Capecitabine, PD-1/CTLA-4 inhibitor (Aiparolitoworixureli injection) Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer NCT03594630EARLY Phase 11 site📍 Houston M.D. Anderson Cancer Center · Tests: Chemotherapy, Patient Observation, Questionnaire Administration, Resection of Rectum Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer NCT06209099NA1 site📍 Beijing Peking University Cancer Hospital & Institute · Tests: Nonoperative Management (NOM), Local Excision (LE), Total Mesorectal Excision (TME) TNT of SCRT+CAPOX vs SCRT+CAPOXIRI for Locally Advanced Rectal Cancer NCT05646511Phase 334 sites📍 Chiba📍 Ehime📍 Fukuoka National Cancer Center Hospital East · Tests: SCRT, CAPOX, CAPOXIRI Surgery vs. Radical Chemoradiotherapy for Esophageal SCC After Neoadjuvant Immunochemotherapy NCT07629817Phase 31 site📍 Zhengzhou Henan Cancer Hospital · Tests: Toripalimab + Nab-paclitaxel + Platinum-based Chemotherapy, Radiation with Concurrent Chemotherapy, Radical Esophagecto… Organ Preservation in Rectal Cancer by Dose Escalated MR Guided Adaptive Radiotherapy NCT07337876Phase 21 site📍 Tübingen University Hospital Tuebingen · Tests: Dose escalated radiotherapy using a 1.5 T MR-Linac Gemcitabine/Cisplatin Plus Cemiplimab With or Without Fianlimab in Localized Muscle-invasive Bladder Cancer (NeoSTOP-IT) NCT06571708Phase 21 site📍 New York Columbia University · Tests: Gemcitabine, Cisplatin, Cemiplimab, Fianlimab
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