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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Pediatric Central Nervous System Tumor

Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients NCT05658731NA2 sites📍 Washington D.C.📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: substructure informed planning, Neurocognitive Testing, MRI Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma NCT01106794n/a1 site📍 Washington D.C. Children's National Research Institute Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloud® Device to Treat Malignant Brain Tumors in Pediatric Patients NCT05293197Phase 13 sites📍 Paris📍 Paris📍 Villejuif Assistance Publique - Hôpitaux de Paris · Tests: SonoCloud® (9 transducers) MICRO-BRAIN 2024: Study on Pediatric Brain Tumors NCT07417085NA1 site📍 Florence Meyer Children's Hospital IRCCS · Tests: Biological samples, Fecal samples Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma NCT06796543NA3 sites📍 Washington D.C.📍 Baltimore📍 Minneapolis Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: Consolidative radiation therapy (cRT) Intensity Modulated PrOton Therapy in Pediatric BRain Tumors (IMPORT) NCT07338526NA1 site📍 Mumbai Tata Memorial Centre · Tests: Intensity-modulated proton therapy (IMPT), Photon-based intensity-modulated radiation therapy (IMRT). Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells NCT07148050Phase 11 site📍 Seattle Seattle Children's Hospital · Tests: SC-CAR.GPC3xIL15.21 CAR T cells Engineering Immune Organoids to Study Pediatric Cancer NCT05890781NA2 sites📍 Villejuif📍 Paris Gustave Roussy, Cancer Campus, Grand Paris · Tests: Skin biopsy, Fresh tumor sample, Blood sample, Healthy tissue from the tumor, Spinal cerebrospinal fluid (SCF) Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma NCT03721068Phase 12 sites📍 Atlanta📍 Chapel Hill UNC Lineberger Comprehensive Cancer Center · Tests: iC9.GD2.CAR.IL-15 T-cells, Cyclophosphamide, Fludarabine Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors NCT04185038Phase 11 site📍 Seattle Seattle Children's Hospital · Tests: SCRI-CARB7H3(s); B7H3-specific chimeric antigen receptor (CAR) T cel A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites📍 Washington D.C.📍 Gainesville University of Florida · Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP li… Lithium Treatment to Prevent Cognitive Impairment After Brain Radiotherapy NCT06051240Phase 22 sites📍 Solna📍 Stockholm Region Stockholm · Tests: Lithium, Placebo Systematic Light Exposure in Pediatric Brain Tumor Survivors NCT05340881NA1 site📍 Houston Baylor College of Medicine · Tests: Bright Light Exposure, Dim Light Exposure, Cognitive Assessment Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors NCT06441331Phase 17 sites📍 San Francisco📍 Cincinnati📍 Philadelphia ITM Solucin GmbH · Tests: Lutetium Lu 177-Edotreotide, Amino Acid Solution Radiation Induced Alterations in Resting State Brain Networks in Pediatric Brain Tumor Patients NCT06185686n/a1 site📍 St Louis Washington University School of Medicine · Tests: Cognitive testing, Resting State MRI/Precision functional mapping Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research NCT04806620n/a1 site📍 Delafield Brain Inflammation Collaborative Pediatric Radiation Therapy Registry NCT07129317n/a2 sites📍 Washington D.C.📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma NCT05717699Phase 11 site📍 Beijing Capital Medical University · Tests: Ad-TD-nsIL12 HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors NCT03911388Phase 13 sites📍 Birmingham📍 St Louis📍 Houston M.D. Anderson Cancer Center · Tests: G207 Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant NCT05843253Phase 220 sites📍 Aurora📍 Washington D.C.📍 Chicago Nationwide Children's Hospital · Tests: Ribociclib, Everolimus, Temozolomide (TMZ) Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors NCT03988283Phase 11 site📍 St Louis Washington University School of Medicine · Tests: Personalized neoantigen DNA vaccine, Papivax Biotech TDS-IM v2.0, Peripheral blood draw Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and Young Adult Patients With Resectable, Recurrent Primary Malignant Brain Tumors NCT06914479Phase 11 site📍 Ann Arbor University of Michigan Rogel Cancer Center · Tests: Ad-hCMV-Flt3L, Ad-hCMV-TK, Biospecimen Collection, Magnetic Resonance Imaging, Survey Administration Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer NCT05106296Phase 11 site📍 Augusta Theodore S. Johnson · Tests: Indoximod, Ibrutinib, Cyclophosphamide, Etoposide, Ibrutinib Systemic Biomarkers to Predict Radiation-Induced Neurocognitive Decline NCT06779487n/a1 site📍 Mumbai Tata Memorial Centre A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors NCT05985161Phase 216 sites📍 Los Angeles📍 Palo Alto📍 Washington D.C. Memorial Sloan Kettering Cancer Center · Tests: Selinexor A Study of 177Lu-DTPA-Omburtamab in Children and Adolescents With Brain Cancer or Cancer That Has Spread to the Central Nervous System (CNS) NCT07698899Phase 17 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: 25 mCi 177Lu- DTPA-omburtamab Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures NCT04085887Phase 1, Phase 21 site📍 Stanford Stanford University · Tests: Panitumumab-IRDye800, Pinpoint-IR9000 endoscopic/handheld device, Explorer Air camera, PDE-NEO-II Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT) NCT06193759Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: Multi-tumor antigen specific cytotoxic T lymphocytes (TSA-T) directed against proteogenomically determined personalized… Utility of PET-MRI in Surveillance of Paediatric Brain Tumours NCT05553899NA1 site📍 Sheffield Sheffield Children's NHS Foundation Trust · Tests: PET-MRI Cerebellar Mutism Syndrome Study NCT02300766n/a32 sites📍 Vienna📍 Leuven📍 Prague Copenhagen University Hospital, Rigshospitalet
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