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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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29 recruiting trials

for Respiratory Distress Syndrome in Premature Infants

LISA vs Endotracheal Surfactant in Preterm Neonates: A Lung Ultrasound Distribution Study NCT07514481NA1 site📍 Doha Hamad General Hospital · Tests: surfactant administration by ETT, surfactant administration by thin catheter Effect of Nasal CPAP Versus NIPPV On Diaphragm Electrical Activity (Edi) In VLBW Preterm Infants NCT06295484NA1 site📍 Toronto Sunnybrook Health Sciences Centre · Tests: Alternating traditional CPAP, NIPPV, and high CPAP Breathing Patterns in Infants Before and After Extubation NCT07542301n/a1 site📍 Newark Christiana Care Health Services · Tests: Observation Less Invasive Surfactant Administration in Late Preterm or Early Term Born Infants NCT06421506NA1 site📍 London King's College Hospital NHS Trust · Tests: Less invasive surfactant administration during high flow nasal cannula treatment Surfactant Therapy Via Supraglottic Airway to Preterm Neonates With RDS in Vietnam NCT07098910NA1 site📍 Hanoi Karolinska Institutet · Tests: Surfactant Administration Through Laryngeal or Supraglottic Airways (SALSA), Intubation - Surfactant administration - E… Duration of Surfactant Administration and Impact on Stabilisation of Vital Parameters in Very Preterm Neonates: 1 Minutes Versus 5 Minutes NCT07261787Phase 41 site📍 Graz Medical University of Graz · Tests: Poractant alfa (Curosurf®) - 1-minute administration, Poractant alfa (Curosurf®) - 5-minute administration Surfactant Administration by Insure or Thin Catheter NCT04445571NA1 site📍 Stockholm Karolinska Institutet · Tests: Thin catheter technique or standard ET-tube for surfactant administration Delayed Versus Immediate Cord Clamping in Preterm Birth NCT07699666NA1 site📍 Tunis Faculty of Medicine of Tunis · Tests: Delayed Umbilical Cord Clamping, Immediate Umbilical Cord Clamping Effects of Flow Magnitude on Cardiorespiratory Stability During Nasal High Flow Therapy in Preterm Infants NCT05908227NA2 sites📍 Mainz📍 Bern Insel Gruppe AG, University Hospital Bern · Tests: NHF high, NHF low, NCPAP Comparison of Continuous Positive Airway Pressure (CPAP) and Non-Invasive Positive Pressure Ventilation (NIPPV) in Preterm Newborns With Respiratory Distress Syndrome. NCT06966752NA1 site📍 Vilnius Vilnius University · Tests: NIPPV, CPAP Prophylactic Surfactant by Thin Endotracheal Catheter for Preterm Infants At Birth: the ProTeCt Trial NCT06557551NA1 site📍 Dublin University College Dublin · Tests: Thin catheter surfactant Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting NCT07344714n/a1 site📍 Rochester Mayo Clinic Utilization of Lung Ultrasound Score in Decision for Minimally Invasive Surfactant Administration NCT07442669NA1 site📍 Hackensack Hackensack Meridian Health · Tests: Lung ultrasound MINImising Total Radiation EXposure in Preterm Infants NCT06975189Phase 21 site📍 Melbourne Western Health, Australia · Tests: Lung ultrasound group, Standard Care High-Frequency Oscillation Ventilation Versus Conventional Mechanical Ventilation in Very Preterm Infants With Perinatal Acute Respiratory Distress Syndrome: Multicenters Randomized Controlled, Superiority Trial NCT03736707NA1 site📍 Chongqing Daping Hospital and the Research Institute of Surgery of th… · Tests: HFOV, CMV How Different Levels of CPAP Affect Oxygen Delivery and Lung Expansion in Preterm Infants NCT07674953NA2 sites📍 Little Rock📍 Little Rock University of Arkansas · Tests: Effective oxygen delivery and lung expansion measurement Optimising Breathing Support at Extubation in Very Preterm Infants: A Clinical Study NCT07251790NA3 sites📍 Melbourne📍 Parkville📍 Saint Albans Murdoch Childrens Research Institute · Tests: Pre-extubation continuous positive airway pressure Evaluation of Serial Lung Ultrasound Data After Surfactant Treatments Applied With Different Methods in Preterm Babies NCT06880016NA1 site📍 Konya Konya City Hospital · Tests: Evaluation of serial lung ultrasound data after ENSURE surfactant treatments, Evaluation of serial lung ultrasound data… Pulmonary Volume Changes During Synchonized Noninvasive Positive Pressure Ventilation NCT07237139n/a1 site📍 Zurich University of Zurich · Tests: Electrical Impedance Tomography (EIT) Calfactant vs Poractant Alfa Using a Less Invasive Technique in Preterm Infants With Respiratory Distress Syndrome NCT07350018Phase 45 sites📍 Bursa📍 Bursa📍 Bursa Uludag University · Tests: Poractant alfa, Calfactant Ventilator Pressure and Optimization of Compliance and Hemodynamics NCT06512935NA1 site📍 Birmingham University of Alabama at Birmingham · Tests: Increase in the PEEP followed by decrease in the PEEP, Decrease in the PEEP followed by increase in the PEEP The NONA-LISA Trial NCT05609877NA4 sites📍 Aalborg📍 Aarhus📍 Copenhagen Copenhagen University Hospital, Rigshospitalet · Tests: Isotonic saline, Less Invasive Surfactant Administration (LISA), Fentanyl, Non-pharmacological standard operating proce… Early Prediction of Lung Injury in Preterm Infants Score NCT07265583n/a1 site📍 Pavia Fondazione IRCCS Policlinico San Matteo di Pavia Influence of Flow Rate Change on CO2 Levels During High Flow Nasal Ventilation (HFNV) in Preterm Infants. NCT06622902NA1 site📍 Haifa Rambam Health Care Campus · Tests: change flow from 6 to 2 LPM. Follow TcCO2 for 3 hours, change flow from 2 to 6 LPM. Follow TcCO2 for 3h Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome NCT06776783Phase 331 sites📍 Little Rock📍 La Jolla📍 Sacramento Aerogen Pharma Limited · Tests: APC-0101 (SF-RI 1 surfactant for inhalation combined with a dedicated delivery system), Control Pragmatic Evaluation of Respiratory Distress Syndrome Treatment in Africa NCT06554522Phase 48 sites📍 Bangui📍 Accra📍 Kumasi Indiana University · Tests: Surfactant Effect of Implementing Evidence Based Practices on Prevention of Associated Nasal Pressure Injuries Among Preterm Neonates With Non-Invasive Respiratory Support NCT06642285NA1 site📍 Kafr ash Shaykh Kafrelsheikh University · Tests: Non Invasive Respiratory Support bundle Forced Oscillometry in Infants With Bronchopulmonary Dysplasia NCT04270045n/a1 site📍 Kansas City Winston Manimtim · Tests: Non-invasive forced airway oscillometry Surfactant Administration Methods in Preterm Infants With RDS: A Swedish Cohort Study NCT07550218n/a1 site📍 Gothenburg Vastra Gotaland Region
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