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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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20 recruiting trials

for Richter Transformation

CD45BE-HSPC + CART-45 Cells NCT07451054Phase 11 site📍 Philadelphia University of Pennsylvania · Tests: CART-45 cells, CD45BE-HSPC Treatment of Chinese Participants With B-Cell Malignancies With BGB-16673, a Bruton Tyrosine Kinase-Targeted Protein-Degrader NCT05294731Phase 1, Phase 229 sites📍 Bengbu📍 Hefei📍 Beijing BeOne Medicines · Tests: Tacabrutideg CHOP Plus Mosunetuzumab as First Line in Patients With Richter´s Syndrome: a Phase II Study of the Spanish Group of CLL NCT06926205Phase 216 sites📍 Barcelona📍 Barcelona📍 L'Hospitalet de Llobregat GELLC (Grupo Español de Leucemia Linfocítica Crónica) · Tests: Mosunetuzumab (IV) A Phase 1/2 Study of UB-VV400 With Rapamycin in Relapsed/Refractory B-cell Malignancies NCT07735533Phase 1, Phase 21 site📍 Nashville Umoja Biopharma · Tests: UB-VV400, Rapamycin (sirolimus) Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naïve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT) NCT05536349Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Pirtobrutinib, Obinutuzumab, Venetoclax, Valacyclovir, Allopurinol A Study of APG-3288 in Relapsed/Refractory Blood Cancers NCT07424833Phase 16 sites📍 Los Angeles📍 Jacksonville📍 Grand Rapids Ascentage Pharma Group Inc. · Tests: APG-3288 Registry of the German CLL Study Group NCT02863692n/a1 site📍 Dresden German CLL Study Group Zanubrutinib in Combination With Odronextamab for the Treatment of Patients With Richter's Transformation NCT06735664Phase 11 site📍 Duarte City of Hope Medical Center · Tests: Biopsy, Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Echocardiography A Study of NX-1607 in Adults With Advanced Malignancies NCT05107674Phase 117 sites📍 Duarte📍 Los Angeles📍 San Francisco Nurix Therapeutics, Inc. · Tests: NX-1607, Paclitaxel Zanubrutinib and Lisocabtagene Maraleucel for the Treatment of Richter's Syndrome NCT05873712Phase 23 sites📍 New York📍 Columbus📍 Salt Lake City Aseel Alsouqi · Tests: Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Cyclophosphamide, Fludarabine Evaluation of Treatment by Glofitamab in Combination With Rituximab or Obinutuzumab Plus CHOP in Patients With RIchter Syndrome NCT06186648Phase 223 sites📍 Amiens📍 Angers📍 Bayonne French Innovative Leukemia Organisation · Tests: Glofitamab + Obinutuzumab Efficacy and Safety of Zanubrutinib Plus Tislelizumab Treatment With or Without Sonrotoclax for Patients With Richter Transformation NCT04271956Phase 211 sites📍 Vienna📍 Copenhagen📍 Berlin German CLL Study Group · Tests: Tislelizumab, Zanubrutinib, Sonrotoclax Phase 2 Study of Glofitamab Monotherapy & With Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab in Richter's Transformation NCT06043674Phase 25 sites📍 Atlanta📍 Boston📍 Boston Christine Ryan · Tests: Glofitamab, Obinutuzumab, Polatuzumab Vedotin, Atezolizumab, Tocilizumab ONO-4538 Study in Patients With Richter's Transformation NCT06936943Phase 210 sites📍 Nagoya📍 Fukuoka📍 Hiroshima Ono Pharmaceutical Co., Ltd. · Tests: ONO-4538 Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial NCT07220187Phase 362 sites📍 Irvine📍 Laguna Hills📍 Orange SWOG Cancer Research Network · Tests: Biospecimen Collection, Computed Tomography, Cyclophosphamide, Doxorubicin Hydrochloride, Echocardiography Test Nemtabrutinib and Pembrolizumab for the Treatment of Richter Transformation, Diffuse Large B-cell Lymphoma Subtype NCT06863402Phase 21 site📍 Buffalo Roswell Park Cancer Institute · Tests: Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Echocardiography, Multigated Acquisition Scan Autologous Stem Cell Transplant Followed by Polatuzumab Vedotin in Patients With B-cell Non-Hodgkin and Hodgkin Lymphoma NCT04491370Phase 1, Phase 21 site📍 Valhalla New York Medical College · Tests: Polatuzumab vedotin A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies NCT05006716Phase 1, Phase 2114 sites📍 Birmingham📍 Phoenix📍 Scottsdale BeOne Medicines · Tests: Tacabrutideg Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL. NCT04771572Phase 18 sites📍 Chicago📍 Boston📍 Chapel Hill Newave Pharmaceutical Inc · Tests: LP-118 DALY II USA/ MB-CART2019.1 for DLBCL NCT04792489Phase 232 sites📍 Birmingham📍 Gilbert📍 Phoenix Miltenyi Biomedicine GmbH · Tests: zamtocabtagene autoleucel (MB-CART2019.1), Cyclophosphamide, Fludarabine, Bendamustine
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