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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Severe Mental Illness

Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study NCT06897670n/a1 site📍 Rochester Mayo Clinic · Tests: Observational assessment using functional near-infrared spectroscopy (fNIRS), a noninvasive, portable brain imaging too… The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. NCT05973851Phase 312 sites📍 Innsbruck📍 Bielefeld📍 Dortmund Dr. Inge Winter · Tests: Esketamine Nasal Product, Ketamine Hydrochloride, Esketamine hydrochloride, Second-line Antidepressants Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure NCT05603104Phase 31 site📍 Ramat Gan Dr. Inge Winter · Tests: Clozapine, Esketamine Nasal Product, Escitalopram, Sertraline, Venlafaxine Triage Survey for Psychiatry Research Eligibility NCT05800925n/a6 sites📍 Boston📍 Watertown📍 New York Adams Clinical · Tests: Survey Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression NCT07226232Phase 35 sites📍 Birmingham📍 Tuscaloosa📍 Portland VA Office of Research and Development · Tests: Psilocybin, Psilocybin Meditative Neurofeedback for Depression NCT06675240Phase 11 site📍 La Jolla University of California, San Diego · Tests: MediNF, ShamMediNF A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms NCT06223880Phase 440 sites📍 Bellflower📍 Lafayette📍 Oceanside Axsome Therapeutics, Inc. · Tests: AXS-05, Bupropion Neural Correlates of Stress and Perceived Control in Adolescent Depression NCT04788524NA1 site📍 Belmont Mclean Hospital · Tests: Computer Task Manipulation University of Iowa Interventional Psychiatry Service Patient Registry NCT04480918n/a1 site📍 Iowa City Mark Niciu · Tests: Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (TMS), Ketamine, Esketamine, Deep Transcranial Magne… Neuromodulation and Attention Deficits in MDD NCT07111169NA1 site📍 Chengdu University of Electronic Science and Technology of China · Tests: intermittent theta burst stimulation (iTBS) intervention Identifying Local Field Potential Biomarkers for Treatment-Resistant Major Depression With Deep Brain Stimulation NCT06542094NA1 site📍 Chengdu West China Hospital · Tests: Deep Brain stimulation Validation of the CIDI 5.0 Against the SCID-5 for Lifetime Mental Disorders NCT07604753n/a1 site📍 Hong Kong The University of Hong Kong · Tests: CIDI-5 A Randomized Neuroimaging Trial of Psilocybin in Depression NCT06072898Phase 21 site📍 Toronto Sunnybrook Health Sciences Centre · Tests: Psilocybin, Microcrystalline cellulose, Supportive psychotherapy Singula Phase 0.1 Primary Care Pilot NCT07834684n/a2 sites📍 Brentwood📍 Mount Kisco Singula Health, Inc. Aerobic Versus Leisure Group for Adolescents With Depression NCT05076214NA4 sites📍 Halmstad📍 Stockholm📍 Stockholm Lund University Hospital · Tests: Aerobic exercise in group, Leisure activities in group Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality NCT05925322NA1 site📍 New York Weill Medical College of Cornell University · Tests: "Engage & Connect" Psychotherapy, Symptom Review and Psychoeducation (SRP) Brain Imaging of Cognition Inn Schizophrenia and Depression NCT04159662n/a1 site📍 Ottawa The Royal Ottawa Mental Health Centre Accelerated Treatment of Depressive Patients With tDCS NCT07444242NA1 site📍 Regensburg University of Regensburg · Tests: Transcranial direct current stimulation RCT of At-Home tDCS for Depression in Pregnancy NCT05097586NA2 sites📍 Toronto📍 Toronto Women's College Hospital · Tests: active tDCS, workbook, sham tDCS Peripheral Neuroimmune Mechanisms of Hyperthermia NCT05366270NA1 site📍 Boston Massachusetts General Hospital · Tests: WBH, Sham Early Severe Illness TrAnslational BioLogy InformaticS in Humans NCT05591924n/a1 site📍 London London Health Sciences Centre Research Institute OR Lawson … · Tests: Phelebotomy, Broncheoalveolar Lavage, Tracheal Aspirate, Rectal Swab Double-blind, Placebo-controlled Study in Adults With Major Depressive Disorder NCT07226661Phase 21 site📍 Garden Grove Supernus Pharmaceuticals, Inc. · Tests: SPN-821 2400 mg, Placebo Study on the Effectiveness and Safety of Temporal Interference Stimulation in Treating Patients With Severe Consciousness Disorders NCT06896279NA2 sites📍 Shanghai📍 Shanghai Huashan Hospital · Tests: TI Stimulation, Sham Stimulation Reward-specific Changes of the Chemical Messenger Dopamine in the Brain of Healthy and Depressed People NCT06675851Phase 41 site📍 Vienna Medical University of Vienna · Tests: WELLBUTRIN SR (Bupropion HCI) Sustained-Release Tablets, 150 mg; GlaxoSmithKline, Cipralex (escitalopram) Health and Work Ability Following Inpatient Treatment for Stress-related Disorders - Follow-up Study of the HARMODI Cohort NCT07757997n/a2 sites📍 Süs📍 Süs Clinica Holistica Engiadina Transdiagnostic Internet-delivered Intervention for Adolescents With Anxiety and Depression NCT06724666NA2 sites📍 Cluj-Napoca📍 Cluj-Napoca Babes-Bolyai University · Tests: Transdiagnostic Internet-delivered intervention A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression NCT07300969Phase 243 sites📍 Bentonville📍 Little Rock📍 Oceanside Draig Therapeutics Ltd · Tests: DT-101, DT-101, Placebo Non-invasive BCI and Application Verification for Depressed People NCT06417437Phase 41 site📍 Shanghai Shanghai Mental Health Center · Tests: SSRI, rTMS, Neuro-Feedback, Game Regulation RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS NCT05977439NA1 site📍 Charleston Medical University of South Carolina · Tests: Single-Pulse Transcranial Magnetic Stimulation, EEG-Synchronized Repetitive Transcranial Magnetic Stimulation (rTMS), C… Protocolized Receptive Music Intervention to Reduce Care Refusal in Nursing Home Residents With Major Neurocognitive Disorders NCT07730957NA12 sites📍 Amiens📍 Garches📍 La Celle-Saint-Cloud LNA SANTE · Tests: Receptive music therapy, Standard Nursing Home Care
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