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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)

EIT-Guided Ventilator Settings in AHRF NCT06936618NA1 site๐Ÿ“ Bangkok Mahidol University ยท Tests: Electrical Impedance Tomography (EIT), Enlight 2100 EIT-Guided PEEP Optimization in Trauma and Postoperative ARDS NCT07313644NA1 site๐Ÿ“ Hanoi Nguyen Dang Thu ยท Tests: EIT-giuded PEEP, Control Effects of Low Tidal Volume and Airway Pressure Release Ventilation on Lung Tissue Mechanics in ARDS Patients Under Mechanical Ventilation: A Prospective Randomized Crossover Study NCT06790875NA1 site๐Ÿ“ Wuhan Union Hospital, Tongji Medical College, Huazhong Universityโ€ฆ ยท Tests: Airway Pressure Release Ventilation (APRV) Digital Early Warning System for Acute Lung Injury in Liver Surgery NCT07070362n/a4 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Chongqing Beijing Tsinghua Chang Gung Hospital Influence of Lung Recruitment Potential on Positive End-Expiratory Pressure (PEEP) Titration Strategies in Acute Respiratory Distress Syndrome (ARDS) Patients. NCT07603310NA1 site๐Ÿ“ Rancagua Hospital Dr. Franco Ravera Zunino ยท Tests: Positive End-Expiratory Pressure (PEEP) Titration guided by Static Compliance, Positive End-Expiratory Pressure (PEEP) โ€ฆ RECOMMEND Platform Trial NCT06526533Phase 33 sites๐Ÿ“ Camperdown๐Ÿ“ Sydney๐Ÿ“ Melbourne Australian and New Zealand Intensive Care Research Centre ยท Tests: Liberal RBC Transfusion, Restrictive RBC Transfusion The Impact of Low Versus High Positive End-expiratory Pressure on Diaphragm Function, Ventilation Efficiency, and Lung Mechanics NCT07188038NA2 sites๐Ÿ“ Gothenburg๐Ÿ“ Gothenburg Vastra Gotaland Region ยท Tests: Low positive end-expiratory pressure, Medium positive end-expiratory pressure, High positive end-expiratory pressure A Single Dose, Dose Escalation Clinical Trial on the Safety, Tolerability and Efficacy of Lyophilized Powder for Inhalation of Recombinant Human Keratinocyte Growth Factor-2 (Rh-KGF-2) in The Treatment of Patients With Acute Respiratory Distress Syndrome NCT07558538EARLY Phase 11 site๐Ÿ“ Shanghai Shanghai Zhongshan Hospital ยท Tests: Recombinant Human Keratinocyte Growth Factor-2 for Inhalation (Lyophilized Powder) Imaging Biomarkers to Stratify the Risk of Barotrauma in ARDS NCT05816954n/a2 sites๐Ÿ“ Catanzaro๐Ÿ“ Milan Universitร  Vita-Salute San Raffaele ยท Tests: Chest Computed Tomography Scan per normal clinical practice Titration of Positive End-expiratory Pressure: Comparison Between Manual Thoracic or Abdominal Compression and Electrical Impedance Tomography NCT07623590NA2 sites๐Ÿ“ Crรฉteil๐Ÿ“ Lyon Centre Hospitalier Saint Joseph Saint Luc de Lyon ยท Tests: PEEP titrations The Effect of Single Lung Ventilation Duration on Postoperative Pulmonary Complications in Thoracic Surgery NCT07100860n/a1 site๐Ÿ“ Ankara Dr Abdurrahman Yurtaslan Ankara Oncology Training and Reseaโ€ฆ ยท Tests: One-Lung ventilation Lung Injury is One of the Primary Causes of Morbidity and Mortality in Critically Ill Patients. These Patients Will be Monitored for: 1) Immune Cell Activation 2) Blood-based Biomarkers. In Vitro Models Derived From These Samples Will be Treated With Novel Agent PIP-2 to Evaluate Its Efficacy. NCT07125079n/a1 site๐Ÿ“ Philadelphia University of Pennsylvania Prone Position Assessed by 3D EIT NCT07083973n/a1 site๐Ÿ“ Beijing Peking Union Medical College Hospital ยท Tests: Prone position BALance: ARDS Deconvolution by Bronchoalveolar Lavage Multiomics and Radiomics NCT07633366n/a1 site๐Ÿ“ Vienna Medical University of Vienna ยท Tests: sampling blood, Lavage with physiologic saline solution Macrophage Programing in Acute Lung Injury: MiniBAL NCT05767671NA1 site๐Ÿ“ Denver William Janssen, MD ยท Tests: Non-Bronchoscopic Mini Bronchoalveolar Lavage EXTEND ARDS-J Esophageal Pressure Study NCT06734988n/a1 site๐Ÿ“ Sapporo Sapporo Medical University Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe Trauma NCT03368092Phase 31 site๐Ÿ“ Strasbourg University Hospital, Strasbourg, France ยท Tests: Dornase Alfa Inhalant Solution [Pulmozyme], Placebos JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record) NCT06703073Phase 241 sites๐Ÿ“ Birmingham๐Ÿ“ Fresno๐Ÿ“ Long Beach PPD Development, LP ยท Tests: Cohort A: vilobelimab, Cohort A: placebo, Cohort B: paridiprubart, Cohort B: placebo, Cohort C: bevacizumab CytOSorb TreatMent Of Critically Ill PatientS Registry NCT05146336n/a28 sites๐Ÿ“ Klagenfurt๐Ÿ“ Vienna๐Ÿ“ Aachen CytoSorbents, Inc ยท Tests: CytoSorb Infants With Severe Acute Respiratory Distress Syndrome: The Prone Trial NCT05002478NA1 site๐Ÿ“ Vienna Medical University of Vienna ยท Tests: Prone positioning Effect of EIT-guided PEEP in ARDS Patients NCT06990477NA17 sites๐Ÿ“ Hefei๐Ÿ“ Shanghai๐Ÿ“ Shanghai Southeast University, China ยท Tests: EIT-guided PEEP A Study of the Efficacy and Safety of Extracorporeal Carbon Dioxide Removal Using PrismaLung+ NCT07326215NA10 sites๐Ÿ“ Beijing๐Ÿ“ Guangzhou๐Ÿ“ Shenzhen Vantive Health LLC ยท Tests: PrismaLung+, Invasive Mechanical Ventilation JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab NCT06701682Phase 241 sites๐Ÿ“ Birmingham๐Ÿ“ Fresno๐Ÿ“ Long Beach PPD Development, LP ยท Tests: Cohort A: vilobelimab, Cohort A: placebo Electrical Impedance Tomography-Based Prognostic Model for ARDS NCT06967207n/a4 sites๐Ÿ“ Guangzhou๐Ÿ“ Wuhan๐Ÿ“ Wuhan XiaoJing Zou,MD ยท Tests: Not applicable- observational study Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome NCT06066502Phase 333 sites๐Ÿ“ Tucson๐Ÿ“ Little Rock๐Ÿ“ La Jolla Beth Israel Deaconess Medical Center ยท Tests: Precision ventilation, Guided usual care ventilation Vadadustat for the Treatment of Nonintubated Acute Respiratory Distress Syndrome Due to Pathogen-Associated Lung Injury NCT07086755Phase 2, Phase 31 site๐Ÿ“ Houston Paul Potnuru ยท Tests: Vadadustat 900mg, Vadadustat 1200mg, Placebo A Study on the Treatment of Patients With Acute Lung Injury Caused by Sepsis Through Microbiota Transplantation NCT07342205Phase 2, Phase 31 site๐Ÿ“ Shanghai Shanghai University of Traditional Chinese Medicine ยท Tests: Placebo control group, Human-derived active intestinal bacterial liquid group Free for Weaning ECMO vs Respiratory Driven Study NCT06876415NA4 sites๐Ÿ“ Lyon๐Ÿ“ Marseille๐Ÿ“ Nice Assistance Publique Hopitaux De Marseille ยท Tests: P0.1 and delta Poeso integration into the decanulation decision ALI/ARDS Clinical Sub-phenotyping Study NCT06123962n/a1 site๐Ÿ“ Beijing China-Japan Friendship Hospital ยท Tests: Collect peripheral blood and bronchoalveolar lavage fluid JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart NCT06701669Phase 241 sites๐Ÿ“ Birmingham๐Ÿ“ Fresno๐Ÿ“ Long Beach PPD Development, LP ยท Tests: Cohort B: paridiprubart, Cohort B: placebo
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