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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Adult Glioma

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma NCT07452458Phase 354 sites📍 Irvine📍 Los Angeles📍 Orange NRG Oncology · Tests: Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Questionnaire Administration, Radiation Therapy hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM) NCT05052957Phase 21 site📍 Cleveland Leland Metheny · Tests: P140K-MGMT, O6-benzylguanine, Photon Based Radiotherapy, temozolomide, Filgrastim Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature NCT06894225Phase 21 site📍 Singapore National Neuroscience Institute · Tests: ACT001 Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma NCT06991101Phase 22 sites📍 Miami📍 New York Baptist Health South Florida · Tests: Ruxolitinib, Temozolomide, Radiation Therapy Evaluate the Role of Anthracycline After Radio Therapy in Patients With Glioblastoma (pGBM). NCT06297512Phase 21 site📍 Florence Iacopo Sardi · Tests: Radiotherapy, Temozolomide, Doxorubicin Prognostic Potential of Olfactory Function in Glioblastoma: a Prospective Observational Study NCT06954636n/a2 sites📍 Essen📍 Münster Sied Kebir · Tests: olfactory testing (threshold and identification test) Dabrafenib and/or Trametinib Rollover Study NCT03340506Phase 438 sites📍 Scottsdale📍 Bethesda📍 Columbus Novartis Pharmaceuticals · Tests: dabrafenib, trametinib Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy NCT07179328Phase 11 site📍 Toronto Sunnybrook Health Sciences Centre · Tests: Focused Ultrasound Next Generation Dome Helmet, Definity® Vial for (Perflutren Lipid Microsphere) Injectable Suspension Relapsed and Progressive Sonic Hedgehog Medulloblastoma With U1 Mutation Registry Study NCT07242963n/a2 sites📍 Houston📍 Houston Mohammad H. Abu Arja Key Longitudinal Associations With Risk and Glioblastoma Outcomes NCT06625684n/a1 site📍 Durham Duke University Combination Therapy for the Treatment of Diffuse Midline Gliomas NCT05009992Phase 232 sites📍 Birmingham📍 Los Angeles📍 San Diego University of California, San Francisco · Tests: ONC201, Radiation Therapy, Paxalisib, DNX-2401 The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203) NCT06146738n/a8 sites📍 San Francisco📍 Boston📍 Leuven Jasper Gerritsen · Tests: Palliative Care, Tumor biopsy, Tumor resection Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors NCT05283330Phase 18 sites📍 Chicago📍 Iowa City📍 Lexington Orano Med Theranostics, SAS · Tests: ²¹²Pb-DOTAM-GRPR1 ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors NCT04732065Phase 17 sites📍 San Francisco📍 Washington D.C.📍 Atlanta Sabine Mueller, MD, PhD · Tests: ONC206, Standard of Care Radiation Therapy, Optional Proton (1H) MR spectroscopy (MRS) A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors NCT06326411Phase 123 sites📍 San Francisco📍 Westwood, Los Angeles📍 Denver Nested Therapeutics, Inc · Tests: NST-628 International HIT-MED Registry (I-HIT-MED) NCT02417324n/a57 sites📍 Aachen📍 Augsburg📍 Berlin Universitätsklinikum Hamburg-Eppendorf DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations NCT06988475Phase 2, Phase 317 sites📍 Belfast📍 Birmingham📍 Bristol Cancer Research UK · Tests: Capmatinib Phase 1 Study of Locoregional Injections of Ex Vivo Expanded Natural Killer Cells NCT04254419Phase 11 site📍 Columbus Nationwide Children's Hospital · Tests: NK cells Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma NCT07506239NA1 site📍 San Francisco University of California, San Francisco · Tests: Laser Interstitial Thermal Therapy (LITT), Magnetic resonance imaging (MRI), Questionnaires Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors NCT07523529Phase 1, Phase 21 site📍 Shenzhen Beijing Biotech · Tests: Autologous dual-target CAR-T cells selected from the predefined target library., Fludarabine, Cyclophosphamide Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors NCT04185038Phase 11 site📍 Seattle Seattle Children's Hospital · Tests: SCRI-CARB7H3(s); B7H3-specific chimeric antigen receptor (CAR) T cel Hypofractionated Radiotherapy NCT06740955NA1 site📍 Changchun The First Hospital of Jilin University · Tests: hypofractionated postoperative radiotherapy, Conventionally fractionated postoperative radiotherapy Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy NCT05180825Phase 225 sites📍 Amiens📍 Angers📍 Besançon University Hospital, Strasbourg, France · Tests: Trametinib, Vinblastine CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults NCT06305910Phase 11 site📍 Minneapolis OX2 Therapeutics · Tests: Treatment with CD200AR-L A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites📍 Washington D.C.📍 Gainesville University of Florida · Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP li… D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients NCT05734560Phase 1, Phase 21 site📍 Durham Darell Bigner · Tests: D2C7-IT, 2141-V11 Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma NCT07551336Phase 11 site📍 Shenzhen Beijing Biotech · Tests: Dual-target CAR-NK cells, Cyclophosphamide, Intracranial catheter/reservoir for locoregional delivery, Fludarabine Brain Glioma Registry Combining Clinical and Imaging Information NCT02619890n/a1 site📍 Seoul Asan Medical Center · Tests: Brain Glioma Registry ADAGiO: Adoptive Cellular Therapy for the TreAtment of Recurrent OliGodendrogliOma (OG) Adult Patients NCT06254326Phase 11 site📍 Gainesville University of Florida · Tests: TTRNA-DC vaccines with GM-CSF, Autologous Hematopoietic Stem cells (HSCs), TTRNA-xALT, Td vaccine DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers. NCT05770544Phase 2, Phase 327 sites📍 Belfast📍 Birmingham📍 Birmingham Cancer Research UK · Tests: Entrectinib
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