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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced/Metastatic Colorectal Adenocarcinoma

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors NCT05733000Phase 21 site๐Ÿ“ Chicago Northwestern University ยท Tests: Biospecimen Collection, Computed Tomography, Devimistat, Fluorouracil, Gemcitabine Hydrochloride A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors NCT07318805Phase 113 sites๐Ÿ“ Duarte๐Ÿ“ Grand Rapids๐Ÿ“ Long Island City Pfizer ยท Tests: PF-08032562, Fulvestrant, Cetuximab, Fluorouracil, Oxaliplatin AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors NCT07094113Phase 139 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Atlanta Amgen ยท Tests: AMG 410, Pembrolizumab, Panitumumab CT-95 in Advanced Cancers Associated With Mesothelin Expression NCT06756035Phase 19 sites๐Ÿ“ Denver๐Ÿ“ Chicago๐Ÿ“ Grand Rapids Context Therapeutics Inc. ยท Tests: CT-95 Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors NCT04771520Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Avapritinib Study of MT-302 in Adults With Advanced or Metastatic Epithelial Tumors NCT05969041Phase 16 sites๐Ÿ“ Darlinghurst๐Ÿ“ Randwick๐Ÿ“ Westmead Myeloid Therapeutics ยท Tests: MT-302 (A) Advanced Therapies for Liver Metastases NCT04622423n/a1 site๐Ÿ“ Milan IRCCS San Raffaele Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors NCT05856981Phase 17 sites๐Ÿ“ Detroit๐Ÿ“ St Louis๐Ÿ“ Canton Sairopa B.V. ยท Tests: ADU-1805, Pembrolizumab Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer NCT04511039Phase 11 site๐Ÿ“ Buffalo Roswell Park Cancer Institute ยท Tests: Trifluridine and Tipiracil Hydrochloride, Talazoparib Tosylate IDOV-Immune for Advanced Solid Tumors NCT06910657Phase 15 sites๐Ÿ“ St Louis๐Ÿ“ Houston๐Ÿ“ San Antonio ViroMissile, Inc. ยท Tests: IDOV-Immune (oncolytic vaccinia virus) A Phase 1 Study of TGI-5 as Monotherapy and in Combination With Nivolumab in Subjects With Locally Advanced/Metastatic Solid Tumors NCT07376707Phase 11 site๐Ÿ“ Shanghai Hefei TG ImmunoPharma Co., Ltd. ยท Tests: TGI-5 A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation NCT06778863Phase 121 sites๐Ÿ“ Scottsdale๐Ÿ“ Tucson๐Ÿ“ Los Angeles Clasp Therapeutics, Inc. ยท Tests: CLSP-1025 Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors NCT06040541Phase 117 sites๐Ÿ“ Sacramento๐Ÿ“ New Haven๐Ÿ“ Sarasota Revolution Medicines, Inc. ยท Tests: RMC-9805, RMC-6236 Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS NCT05379985Phase 1, Phase 221 sites๐Ÿ“ Orange๐Ÿ“ Santa Monica๐Ÿ“ Tampa Revolution Medicines, Inc. ยท Tests: RMC-6236 A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors NCT07488676Phase 1, Phase 221 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ Miami Astellas Pharma Global Development, Inc. ยท Tests: ASP546C A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors NCT07229313Phase 17 sites๐Ÿ“ Santa Monica๐Ÿ“ New Have๐Ÿ“ Camperdown Kivu Bioscience Inc. ยท Tests: KIVU-107 A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors NCT04657068Phase 1, Phase 288 sites๐Ÿ“ Birmingham๐Ÿ“ Scottsdale๐Ÿ“ Little Rock Artios Pharma Ltd ยท Tests: ART0380, Gemcitabine, Irinotecan A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors NCT06657144Phase 130 sites๐Ÿ“ Tucson๐Ÿ“ Duarte๐Ÿ“ Aurora Coherus Oncology, Inc. ยท Tests: CHS-114, Toripalimab, 5 Fluorouracil, Cisplatin Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours. NCT07148128Phase 1, Phase 24 sites๐Ÿ“ Dallas๐Ÿ“ San Antonio๐Ÿ“ Toronto Auricula Biosciences Inc. ยท Tests: WEF-001 Dual-Targeting CAR-NK Cells in Biomarker-Selected Advanced Colorectal Cancer NCT07589517Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: EB-DUO-CAR-NK-CEA/GCC, Lymphodepletion The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia. NCT07224464NA1 site๐Ÿ“ Rochester New Phase Ltd. ยท Tests: The Sarah Nanotechnology System - intended to deliver thermal energy to malignant cells for the purpose of thermal destโ€ฆ A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors NCT07094204Phase 120 sites๐Ÿ“ Santa Monica๐Ÿ“ Atlanta๐Ÿ“ Jefferson Astellas Pharma Inc ยท Tests: ASP5834, panitumumab TARGETed Therapy Drug MONITOring in DIGestive Oncology NCT05443087NA29 sites๐Ÿ“ Amiens๐Ÿ“ Auxerre๐Ÿ“ Avignon UNICANCER ยท Tests: Blood sampling to build population pharmacokinetics model A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations NCT06835569Phase 114 sites๐Ÿ“ Orlando๐Ÿ“ Tampa๐Ÿ“ Boston Alterome Therapeutics, Inc. ยท Tests: ALTA3263, cetuximab, mFOLFOX6, Pembrolizumab, Pemetrexed + Cisplatin /Carboplatin A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations NCT07629960Phase 1, Phase 216 sites๐Ÿ“ Sarasota๐Ÿ“ Tampa๐Ÿ“ Baton Rouge Blueprint Medicines Corporation ยท Tests: BLU-924 A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors NCT05592626Phase 1, Phase 219 sites๐Ÿ“ Sacramento๐Ÿ“ Celebration๐Ÿ“ Miami Marengo Therapeutics, Inc. ยท Tests: STAR0602, Irinotecan (Camptosar), Docetaxel (Taxotere) FOG-001 in Locally Advanced or Metastatic Solid Tumors NCT05919264Phase 1, Phase 233 sites๐Ÿ“ Phoenix๐Ÿ“ Scottsdale๐Ÿ“ Tucson Parabilis Medicines, Inc. ยท Tests: FOG-001, mFOLFOX-6, Nivolumab, Trifluridine/tipiracil, Bevacizumab First in Human Study of SIM0610 in Solid Tumors NCT07348211Phase 17 sites๐Ÿ“ Chongqing๐Ÿ“ Harbin๐Ÿ“ Shenyang Jiangsu Simcere Pharmaceutical Co., Ltd. ยท Tests: SIM0610 for Injection, SIM0610 for Injection A Study of MGC026 in Participants With Advanced Solid Tumors NCT06242470Phase 112 sites๐Ÿ“ Los Angeles๐Ÿ“ Grand Rapids๐Ÿ“ Lake Success MacroGenics ยท Tests: MGC026 Dose Escalation, MGC026 Dose for Expansion A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors NCT07020117Phase 114 sites๐Ÿ“ Duarte๐Ÿ“ Irvine๐Ÿ“ Miami Aktis Oncology, Inc. ยท Tests: [225Ac]Ac-AKY-1189 (therapeutic), [64Cu]Cu-AKY-1189 (imaging)
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