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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Chronic Rhinosinusitis With Nasal Polyps

Upper Airway Inflammation and Olfaction: Mechanisms of Loss and Recovery NCT06776042NA1 site📍 Brussels Cliniques universitaires Saint-Luc- Université Catholique d… · Tests: Nasal brushing of the olfactory cleft, Smell testing 3D Printing to Improve Nasal Irrigation Outcome NCT06118554NA1 site📍 Columbus Ohio State University · Tests: Irrigation head position Sinonasal Microbiome Transplant as a Therapy for Chronic Rhinosinusitis (CRS). NCT07184684Phase 2, Phase 31 site📍 Helsingborg Region Skane · Tests: Sinonasal microbiome transplant procedure., Placebo saline transplant Metabolic and Immunologic Biomarkers in Chronic Rhinosinusitis With Nasal Polyps NCT07860411n/a1 site📍 Sanliurfa Harran University · Tests: Nasal polyp tissue and blood sampling, Nasal mucosa and blood sampling Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients. NCT06892704n/a1 site📍 Chicago Northwestern University · Tests: Dupilumab - Standard Dose Real Life Study of Biologicals in Patients With Severe CRSwNP NCT05938972n/a1 site📍 Ghent University Hospital, Ghent · Tests: Mepolizumab Effect of Dupilumab on Nasal Epithelial Barrier Function in Patients With CRSwNP NCT06398873n/a1 site📍 Vienna Medical University of Vienna · Tests: Dupilumab 300 MG/2 ML Subcutaneous Solution [DUPIXENT] Efficacy and Safety of Fully Resorbable Sinus Drug-eluting Stents in Patients With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps After Surgery: A Prospective, Randomized Controlled Trial NCT07498374NA1 site📍 Xi'an Tang-Du Hospital · Tests: the fully degradable sinus stent, intranasal corticosteroids, oral corticosteroids Prospective, Non-interventional Single-arm Study With Tezepelumab to Investigate the Change in Clinical and Patient-reported Outcomes in Patients With CRSwNP in Real-world (PETRICHOR) NCT07633158n/a19 sites📍 Berlin📍 Bochum📍 Braunschweig AstraZeneca Mepolizumab and in Office-office Nasal Polypectomy in Patients With Chronic Rhinosinusitis (CRS). NCT07814924Phase 47 sites📍 Barakaldo📍 Jerez de la Frontera📍 Madrid Instituto de Investigación Marqués de Valdecilla · Tests: surgical arm, Mepolizumab 100 MG, combined arm Biologics in Chronic Rhinosinusitis With Nasal Polyposis NCT06824649Phase 43 sites📍 Gainesville📍 Portland📍 Charleston Medical University of South Carolina · Tests: Biologic Agents A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP) NCT06338995Phase 3202 sites📍 Birmingham📍 Birmingham📍 Huntsville Eli Lilly and Company · Tests: LY3650150, Placebo, Standard therapy for INCS Rhinosinusitis Italian Network: the Italian Registry for Severe, Uncontrolled Chronic Rhinosinusitis NCT05935683n/a1 site📍 Rozzano Italian Academy of Rhinology · Tests: Severe Uncontrolled Chronic Rhinosinusitis patients (CRS) Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps NCT06850805Phase 324 sites📍 Huntsville📍 Gilbert📍 Los Angeles Optinose US Inc. · Tests: OPN-375, Placebo A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) NCT07782957Phase 34 sites📍 Sherman Oaks📍 Greenville📍 Plano GlaxoSmithKline · Tests: GSK5784283, Placebo, Standard of Care Interleukin-4Ra Blockade by Dupilumab Decreases Staphylococcus Colonization and Increases Microbial Diversity in CRSwNP NCT05094570Phase 41 site📍 Charlottesville University of Virginia · Tests: Dupilumab Prefilled Syringe BIOlogics in Severe Nasal POlyposis SurvEy.: a French Registry NCT06501807NA2 sites📍 Lille📍 Lille University Hospital, Lille · Tests: Biologic treatments available in Chronic Rhinosinusitis with Nasal Polyps (dupilumab, mepolizumab and benralizumab acco… Complete Remission After Treatment With Biologics for Nasal Polyps NCT07268313Phase 46 sites📍 Copenhagen📍 Hillerød📍 Køge Copenhagen University Hospital, Rigshospitalet · Tests: DUPIXENT®, NUCALA®, Dupi discontinuation, Mepo discontinuation Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis NCT07290140NA10 sites📍 Birmingham📍 San Diego📍 Colorado Springs Airiver Medical, Inc. · Tests: Airiver ESSpand DCB, ESS Real-life Evaluation of the Efficacy of Biologicals in Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP) NCT06683261n/a8 sites📍 Aalst📍 Bruges📍 Brussels Universitaire Ziekenhuizen KU Leuven · Tests: Omalizumab, Dupilumab, Mepolizumab 100 mg A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) NCT07782970Phase 33 sites📍 Los Angeles📍 Tulsa📍 San Juan GlaxoSmithKline · Tests: GSK5784283, Placebo, Standard of Care Clinical Trial of TQC2731 Injection in Patients With Chronic Sinusitis and Nasal Polyps NCT07107256Phase 360 sites📍 Fuyang📍 Hefei📍 Beijing Shanghai Chia Tai Tianqing Pharmaceutical Technology Develo… · Tests: TQC2731 injection, Placebo of TQC2731 Effect of Full-House ESS With Nasopharyngeal Lymphoid Tissue Ablation on Nasal Polyps NCT07245329NA1 site📍 Wuhan Tongji Hospital · Tests: Nasopharyngeal Lymphoid Tissue Ablation, Full-House Endoscopic Sinus Surgery Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training NCT07681973NA1 site📍 Cleveland The Cleveland Clinic · Tests: Smell Training Basal Instincts: Towards Better Understanding of Basal Cell Function in Chronic Rhinosinusitis With Nasal Polyps NCT06129552n/a1 site📍 Leuven Universitaire Ziekenhuizen KU Leuven · Tests: Conchotomy, aesthetic nose surgery or functional endoscopic sinus operation Biomarkers of Response to Mepolizumab Treatment in Patients With Nasal Polyps With or Without Bronchial Asthma NCT05708300n/a2 sites📍 Thessaloniki📍 Thessaloniki Aristotle University Of Thessaloniki · Tests: Mepolizumab 100 MG [Nucala] CRS Questionnaire Validation Project NCT06970977n/a32 sites📍 Santa Monica📍 Chicago📍 Boston The European Forum for Research and Education in Allergy an… A Study of BBT002 in Healthy Volunteers (HVs) and in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) With or Without Comorbid Asthma NCT07436949Phase 1, Phase 212 sites📍 Beijing📍 Guangzhou📍 Changsha Bambusa Therapeutics · Tests: BBT002, Placebo In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps NCT02975310NA4 sites📍 Vancouver📍 London📍 Ottawa Ottawa Hospital Research Institute · Tests: Endoscopic polypectomy in clinic (EPIC), Endoscopic Sinus Surgery (ESS), General Anesthesia, Local and topical anesthes… Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal Polyps NCT05009758NA1 site📍 Vienna Medical University of Vienna · Tests: Blood sampling, Nasosorption, Oral sampling, Bronchoscopy, Nasal biopsy
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